supported by Chongqing Municipal Natural Science Foundation (CSTB2022NSCQ-MSX1366);National Natural Science Foundation of China (81702182,81874087);Chongqing Outstanding Young Talent Supporting Program (cstc2024ycjhbgzxm0031);the Special Project for Talent Development of Xinqiao Hospital (2022XKRC006)。
Intervertebral disc degeneration(IDD)is a major cause of discogenic pain,and is attributed to the dysfunction of nucleus pulposus,annulus fibrosus,and cartilaginous endplate(CEP).Osteopontin(OPN),a glycoprotein,is hig...
L.Zhao was supported by the National Natural Science Foundation of China(12161052);Natural Science Foundation of Gansu,China(21JR7RA240).
In this paper,we focus on asymptotic speeds of spread for a reaction-diffusion two-group SIR epidemic model with constant recruitment,which lacks the comparison principle.More precisely,if R_(0)<1,then the solution of...
supported by grant from the National Natural Science Foundation of China(No.82002693 and No.81803022);the Natural Science Foundation of Shaanxi Province(No.2022JQ-903 and No.2020JQ-519).
Tumor-derived exosomes have been shown to play a key role in organ-specific metastasis,and the androgen receptor regulates prostate cancer(PCa)progression.It is unclear whether the androgen receptor regulates the recr...
support by the National Key R&D Program of China (2022YFA1104900,2022YFA0806301);the National Natural Science Foundation of China (22075127,31972926,82371725,and 32301204);the Guangdong Key Research and Develop-ment Plan (2019B020234003).
Inflammatory cytokine storms can trigger disease exacerbation and even death and have reached a consensus in the clinical treatment of acute organ failure.However,the existing strategies remain a great challenge to ef...
supported by grants from the National Natural Science Foundation of China(82172430 and 82272505);University Grants Committee,Research Grants Council of the Hong Kong Special Administrative Region,China(14108720,14121721,14202920,N_CUHK472/22,C7030-18G,T13-402/17-N and AoE/M-402/20);Heath Medical Research Fund(HMRF)Hong Kong(16170951,17180831,08190416 and 09203436);Hong Kong Innovation Technology Commission Funds(PRP/050/19FX).
Lacking self-repair abilities,injuries to articular cartilage can lead to cartilage degeneration and ultimately result in osteoarthritis.Tissue engineering based on functional bioactive scaffolds are emerging as promi...
supported by grants from the National Natural Science Foundation of China(31772106)and the Natural Science Foundation of Fujian Province(2021J06015).The funders had no role in the study design,data collection and analysis,decision to publish,or preparation of the manuscript.
The retromer complex,composed of the cargo-selective complex(CSC)Vps35-Vps29-Vps26 in complex with the sorting nexin dimer Vps5-Vps17,mediates the sorting and retrograde transport of cargo proteins from the endosomes ...
The recruitment solves the problem of the source of labor force in the enterprise. If the work is not done properly, it will not only add unnecessary burden to the work of the employees, but also seriously affect the ...
Supported by the National Natural Science Foundation of China,No.81570543 and No.81560104
BACKGROUND Massive hepatocyte death is the core event in acute liver failure(ALF).Gasdermin D(GSDMD)-mediated pyroptosis is a type of highly inflammatory cell death.However,the role of hepatocyte pyroptosis and its me...
Background: Zinner syndrome represents a rare congenital malformation of the urinary tract. It comprises a constellation of Wolffian duct anomalies and is almost exclusively encountered as a classic triad of seminal v...