supported by Shanxi“1331 Project”Key Subjects Construction,No.1331KSC(to JSQ);Science Research Start-up Fund for Doctors of Shanxi Province,No.SD2011(to TL);Science Research Start-Up Fund for Doctors of Shanxi Medical University,No.XD2017(to TL)。
Agomelatine is a selective agonist of melatonin receptor 1A/melatonin receptor 1B(MT/MT)and antagonist of 5-hydroxytryptamine 2C receptors.It is used clinically to treat major depressive episodes in adults.The pro-chr...
Supported by Ministerio de Economía,Industria y Competitividad,Instituto de Salud Carlos III,Madrid,Spain,No. PI16/01514
BACKGROUND Neuropsychiatric symptoms(NPS)have been insufficiently examined in persons with aphasia(PWA)because most previous studies exclude participants with language and communication disorders.AIM To report a two-p...
A harmonious society is a beautiful social form that people intend to create whose main form of expression is that everyone can pay attention to social morality,thus it can reflect the humanity of society.With the con...
Previous clinical trials have demonstrated the efficacy of yokukansan, a traditional Japanese medicine, for the treatment of behavioral and psychological symptoms of dementia (BPSD). However, less evidence is availabl...
This work was supported by the Japan Society for the Promotion of Science[JP16KK0053,JP17K02105];Kurita Water and Environment Foundation[17K010];Environment Research and Technology Development Fund[(S-15-2(1)(3)Predicting and Assessing Natural Capital and Ecosystem Services(PANCES))];Ecological Society of China;Tohoku Regional Development Association;Research Institute for Humanity and Nature[No.14200126];Toyota Foundation[D17-N-0107]。
Intruduction:We assessed recent trends in children's connection with nature over the period of 2000-2015,using indices of wildlife awareness that focus on changes in wildlife abundance and the level of apathy among ch...
Objective To investigate the apathy and neuropsychological characteristics of newly diagnosed Parkinson’s disease(PD)patients.Methods Eighty-two newly diagnosed PD patients and 30 matched healthy controls by age,sex ...
Background: Apathy occurs frequently in patients with Parkinson’s disease (PD), and has a negative impact on activities of daily living through loss of motivation. Pramipexole (PPX), which shows preferential affinity...
Objective: The purpose of this study is to investigate habitual leisure-time activities (physical and non-physical leisure activities) in patients with Parkinson’s disease (PD), and to determine any potential benefit...
Apathy is one of the least investigated symptom of Parkinson disease (PD). In the article there are data of frequency, diagnostic features, pathophysiology and treatment of apathy in PD. The aim of the investigation...
Parkinson’s disease is a neurodegenerative disorder characterized by motor, autonomic, and neuropsychiatric symptoms, among the latter, apathy has been found to be present in up to 70% of patients. The main objective...