PRAMIPEXOLE

作品数:16被引量:39H指数:3
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相关领域:医药卫生更多>>
相关作者:李超更多>>
相关机构:山东大学南京工业大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》《Translational Neurodegeneration》《Advances in Parkinson's Disease》更多>>
相关基金:国家自然科学基金北京市自然科学基金更多>>
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Pramipexole in Treatment Resistant Depression: A Case Review
《Pharmacology & Pharmacy》2023年第7期223-227,共5页Nada Abdallah Jeffrey Kahn 
Pramipexole is a dopamine agonist used in the treatment of Parkinson’s disease and Restless legs syndrome. Although off-label, the use of Pramipexole as an adjunct therapy in treatment resistant depression has recent...
关键词:PRAMIPEXOLE Treatment Resistant Depression Augmentation Dopamine Agonism Geriatric Psychiatry 
Pramipexole inhibits astrocytic NLRP3 inflammasome activation via Drd3-dependent autophagy in a mouse model of Parkinson’s disease被引量:5
《Acta Pharmacologica Sinica》2023年第1期32-43,共12页An-qi Dong Ya-ping Yang Shu-min Jiang Xiao-yu Yao Di Qi Cheng-jie Mao Xiao-yu Cheng Fen Wang Li-fang Hu Chun-feng Liu 
This work was supported by grants from the National Natural Science Foundation of China (81671250,82071420,82101333,81870997,82171251);Jiangsu Provincial Key R&D Program (BE2018658);the Key Project of Natural Science Foundation of Jiangsu Provincial Higher Education Institutions (21KJA180003);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD).
Inflammation is one of the pathogenic processes in Parkinson’s disease(PD).Dopamine receptor agonist pramipexole(PPX)is extensively used for PD treatment in clinics.A number of studies show that PPX exerts neuroprote...
关键词:Parkinson's disease neuroinflammation astrocytes NLRP3 inflammasome AUTOPHAGY dopamine D3 receptor 
Pramipexole, a dopamine D3/D2 receptor-preferring agonist, attenuates reserpine-induced fibromyalgia-like model in mice被引量:3
《Neural Regeneration Research》2022年第2期450-458,共9页Carlos Pereira Martins Rodrigo Sebben Paes Gabriela Mantovani Baldasso Eduarda Gomes Ferrarini Rahisa Scussel Rubya Pereira Zaccaron Ricardo Andrez Machado-de-Avila Paulo Cesar Lock Silveira Rafael Cypriano Dutra 
supported by grants from Programa de Pos-graduacao em Neurociencias(PGN),Programa INCT-INOVAMED(grant No.465430/2014-7);Fundacao de Apoio à Pesquisa e Inovacao do Estado de Santa Catarina(FAPESC);Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior(CAPES)。
Fibromyalgia(FM) is a complex pathology described as persistent hyperalgesia including somatic and mood dysfunctions, depression and anxiety. Although the etiology of FM is still unknown, a significant decrease in bio...
关键词:DOPAMINE dopaminergic system FIBROMYALGIA HYPERALGESIA pain PRAMIPEXOLE RESERPINE 
Problems Associated with Non-Ergot Dopamine Agonist Maintenance Therapy in Patients with Advanced Parkinson’s Disease
《Advances in Parkinson's Disease》2019年第3期35-41,共7页Makoto Shiraishi Futaba Maki Naoshi Sasaki Yasuhiro Hasegawa 
Non-ergot dopamine agonists have become popular for treating motor complications associated with long-term use of levodopa-containing drugs. We conducted a retrospective study in which we identified clinical problems ...
关键词:Parkinson’s Disease Non-Ergot Dopamine Agonist WEARING-OFF ROPINIROLE PRAMIPEXOLE 
Pathological Gambling after Administration of Pramipexole
《Case Reports in Clinical Medicine》2018年第5期349-351,共3页Konstantinos Kontoangelos Marina Ecomomou Charalambos Papageorgiou 
Parkinson’s disease is a common condition usually treated by dopaminergic agents and many behavioral abnormalities such as impulse control disorders (ICD) are connected with that usage. Pathological gambling, a form ...
关键词:PRAMIPEXOLE PATHOLOGICAL GAMBLING SIDE Effects PARKINSON Disease 
Reassessment subacute MPTP-treated mice model of Parkinson disease
《中国药理学与毒理学杂志》2017年第10期1024-1025,共2页Lu WEN Yu-he YUAN Nai-hong CHEN 
supported by National Natural Science Foundation of China(81373997,U1402221,81573640 and 81603316);Beijing Natural Science Foundation(7161011);Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study(BZ0150);CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2M-1-004);Key Research and Development Project of Hunan Province(2015SK2029-1);Scientific Research Foundation of the Higher Education Institutions of Hunan Province(15K091)
OBJECTIVE(1) To estimate the value of the subacute MPTP mouse model in aspects of behavioral performance,biochemical changes and pathological abnormalities.(2) To find effective positive drugs.METHODS Male C57 BL/6 mi...
关键词:subacute MPTP model Parkinson disease SELEGILINE PRAMIPEXOLE Α-SYNUCLEIN 
Reassessment of subacute MPTP-treated mice as animal model of Parkinson's disease被引量:25
《Acta Pharmacologica Sinica》2017年第10期1317-1328,共12页Qiu-shuang ZHANG Yang HENG Zheng MOU Ju-yang HUANG Yu-he YUAN Nai-hong CHEN 
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model remains the most commonly used animal model of Parkinson's disease (PD). There are three MPTP-treatment schemes: acute, subacute and chronic. Consi...
关键词:Parkinson's disease MPTP model SELEGILINE PRAMIPEXOLE medopar behavioral compensation ASTROCYTES Α-SYNUCLEIN blood brain"barrier myelin sheath 
Alpha-Dihydroergocryptine vs. Pramipexole as Adjunct Symptomatic Treatment of Idiopathic Parkinson’s
《Advances in Parkinson's Disease》2015年第1期1-8,共8页Ulises Rodríguez Ortiz Daniel San- Juan Francesco Scarci 
A randomized, double blind, and active reference-controlled study was carried out among 116 patients suffering from idiopathic Parkinson’s disease (PD). The aim of the study was to compare the safety and efficacy of ...
关键词:ADJUNCT Symptomatic Therapy Alpha-Dihydroergocryptine PRAMIPEXOLE IDIOPATHIC Parkinson’s Disease Motor Complications UPDRS 
Self-Reported Adherence after Overnight Switching from Immediate- to Extended-Release Pramipexole in Parkinson’s Disease
《Advances in Parkinson's Disease》2015年第1期13-19,共7页Mutsumi Iijima Mikio Osawa Kenji Maruyama Shinichiro Uchiyama Kazuo Kitagawa 
Background: Drug adherence decreased in patients with Parkinson’ s disease (PD) because of taking many different types of drugs. We evaluated drug adherence after switching from immediate-release (IR) to once-daily e...
关键词:Parkinson’s Disease Timing ADHERENCE PRAMIPEXOLE EXTENDED-RELEASE Immediate-Release Motor Function 
Efficacy of Pramipexole for Treatment of Apathy in Parkinson’s Disease被引量:3
《International Journal of Clinical Medicine》2014年第15期885-889,共5页Hiroaki Oguro Katsuhiko Kadota Masaki Ishihara Kazunori Okada Shuhei Yamaguchi 
Background: Apathy occurs frequently in patients with Parkinson’s disease (PD), and has a negative impact on activities of daily living through loss of motivation. Pramipexole (PPX), which shows preferential affinity...
关键词:PRAMIPEXOLE APATHY Parkinson’s disease DEPRESSION UPDRS 
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