NEUROPATHIES

作品数:34被引量:47H指数:4
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相关期刊:《Chinese Journal of Integrative Medicine》《Journal of Diabetes Mellitus》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
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Shared mechanisms and pathological phenotypes underlying aminoacyl-tRNA synthetase-related neuropathies
《Neural Regeneration Research》2026年第1期312-313,共2页Elena R.Rhymes James N.Sleigh 
funding from the Medical Research Council (MR/S006990/1, MR/Y010949/1);the Rosetrees Trust (M806);the UCL Neurogenetic Therapies Programme funded by The Sigrid Rausing Trust and the UCL Therapeutic Acceleration Support scheme supported by funding from MRC IAA 2021 UCL MR/X502984/1 (to JNS)。
Charcot-Marie-Tooth disease(CMT) is a heterogeneous group of inherited peripheral neuro pathies;it is characterized by muscle weakness and wasting,as well as sensory dysfunction,that typically begins during adolescenc...
关键词:conduction DEGENERATE typically 
Base and translation of β-glucocerebrosidase and its transporter LIMP-2 in neuropathies
《Neural Regeneration Research》2026年第1期314-315,共2页Philipp Arnold Friederike Zunke 
supported by the Michael J Fox Foundation (to PA and FZ)。
The lysosomal enzyme β-glucocerebrosidase(GCase) belongs to the family of glycosidases and hydrolyses the glycosphingolipid glucosylceramide(GluCer) into glucose and ceramide. The enzyme is of central importance for ...
关键词:TRANSLATION belongs SID 
Neuronal trafficking as a key to functional recovery in immune-mediated neuropathies
《Neural Regeneration Research》2024年第11期2331-2332,共2页Felix Kohle Michael Schroeter 
supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation):project ID 431549029-SFB 1451(to MS).
Immune-mediated neuropathies are rare diseases of the peripheral nervous system(PNS),substantially affecting patients’functionality and quality of life.They are amenable to immunomodulatory treatments,which in many c...
关键词:DISEASES AUTOIMMUNE 
Focus on LPA signaling:a promising therapeutic target to foster regeneration in immune-mediated neuropathies
《Neural Regeneration Research》2023年第12期2651-2652,共2页Fabian Szepanowski Mark Stettner 
Lysophospholipids are metabolites of glycerophospholipids and sphingolipids that are commonly found as lipid constituents of cell membranes.In addition to their function as structural membrane components,certain membe...
关键词:LIPIDS THERAPEUTIC FOCUS 
High-Intensity Interval Training v/s Steady-State Cardio in Rehabilitation of Neurological Patients
《Open Journal of Therapy and Rehabilitation》2023年第2期35-44,共10页Thorin Thorbjørnssønn Birkeland 
Neuropathy is nerve damage that can cause chronic neuropathic pain, which is challenging to cure and has a significant financial burden. Exercise therapies, including High-Intensity Interval Training (HIIT) and steady...
关键词:Neurological Diseases NEUROPATHIES High-Intensity Interval Training (HIIT) Steady-State Cardio EXERCISE 
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules
《四川生理科学杂志》2023年第2期358-358,共1页Qinqin Cui 
Complex diseases often involve the interplay between genetic and environmental factors. Charcot-Marie-Tooth type 2neuropathies (CMT2) are a group of genetically heterogeneous disorders, in which similar peripheral neu...
关键词:stress GRANULES Marie 
TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice被引量:2
《Acta Pharmacologica Sinica》2023年第1期92-104,共13页Chang-jie Shi Jun-jiang Lian Bo-wen Zhang Jia-xue Cha Qiu-hong Hua Xiao-ping Pi Yu-jun Hou Xin Xie Ru Zhang 
This work was supported by grants from the Ministry of Science and Technology of China(2017YFA0104002);the Chinese Academy of Sciences(XDA16010202);the National Natural Science Foundation of China(81730099).
Promoting adult neurogenesis in the enteric nervous system(ENS)may be a potential therapeutic approach to cure enteric neuropathies.Enteric glial cells(EGCs)are the most abundant glial cells in the ENS.Accumulating ev...
关键词:enteric glial cells enteric neuropathies TGFβR-1/ALK5 VCR RepSox GASTROENTEROLOGY 
Automatic counting of retinal ganglion cells in the entire mouse retina based on improved YOLOv5
《Zoological Research》2022年第5期738-749,共12页Jing Zhang Yi-Bo Huo Jia-Liang Yang Xiang-Zhou Wang Bo-Yun Yan Xiao-Hui Du Ru-Qian Hao Fang Yang Juan-Xiu Liu Lin Liu Yong Liu Hou-Bin Zhang 
supported by the National Natural Science Foundation of China (61405028 to J.Z.,81770935 to H.B.Z.);Fundamental Research Funds for the Central Universities (University of Electronic Science and Technology of China)(ZYGX2019J053 to J.Z.);Department of Science and Technology of Sichuan Province,China (2020YJ0445 to H.B.Z.)。
Glaucoma is characterized by the progressive loss of retinal ganglion cells (RGCs),although the pathogenic mechanism remains largely unknown.To study the mechanism and assess RGC degradation,mouse models are often use...
关键词:Retinal ganglion cell Cell counting Glaucomatous optic neuropathies Deep learning Improved YOLOv5 
Neuromyelitis optica spectrum disorders and anti-myelin oligodendrocyte glycoprotein positive optic neuropathies被引量:2
《International Journal of Ophthalmology(English edition)》2022年第7期1095-1107,共13页Patrick Murtagh Amy Coman Kirk Stephenson Maria Gaughan David Ryan Graeme McNeill Christopher McGuigan Lorraine Cassidy 
AIM: To describe the clinical characteristics and treatments associated with antibody positive optic neuropathies including anti-myelin oligodendrocyte glycoprotein(MOG) and anti-aquaporin 4(AQP4), alongside diagnosti...
关键词:neuromyelitis anti-myelin oligodendrocyte glycoprotein ANTIBODY anti-aquaporin 4 
Impacts of statin and metformin on neuropathy in patients with type 2 diabetes mellitus: Korean Health Insurance data被引量:1
《World Journal of Clinical Cases》2021年第33期10198-10207,共10页Hong Ki Min Se Hee Kim Jong Han Choi Kyomin Choi Hae-Rim Kim Sang-Heon Lee 
Supported by the Konkuk University Medical Center Research Grant 2020.
BACKGROUND Neuropathy is a common chronic complication in type 2 diabetes mellitus(T2DM).Statin and metformin are commonly used medications in T2DM patients,and some studies showed statin-or metformin-induced neuropat...
关键词:Diabetes mellitus NEUROPATHIES Hydroxymethylglutaryl-CoA reductase inhibitors METFORMIN 
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