RADIOIMMUNOIMAGING

作品数:14被引量:38H指数:5
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相关领域:医药卫生更多>>
相关期刊:《World Journal of Gastroenterology》《Chinese Medical Journal》《Chinese Medical Sciences Journal》《Chinese Journal of Cancer Research》更多>>
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Preliminary radioimmunoimaging and biodistribution of ^131iodine-labeled single-chain antibody fragment against progastrin-releasing peptide(31-98) in small cell lung cancer xenografts被引量:1
《Chinese Medical Journal》2014年第11期2007-2011,共5页Hong Zhihui Shi Yizhen Liu Zengli Zhou Xiaolin Yang Yi Tang Jun 
Background Monoclonal antibodies (mAbs) such as DD3,raised against progastrin-releasing peptide(31-98) (ProGRP(31-98)) antigen,have been used to target small cell lung cancer (SCLC).However,as an intact mAb,...
关键词:131I-anti-ProGRP(31-98)scFv ProGRP(31-98) small cell lung cancer BIODISTRIBUTION RADIOIMMUNOIMAGING 
Application of labeled radioimmunoimaging tracing in detecting pulmonary embolism in rabbits after bone cement perfusion and relevant treatment effects被引量:5
《Chinese Medical Journal》2011年第23期4029-4033,共5页QI Xiang-bei ZHANG Ying-ze PAN Jin-she MA Li-jie WANG Jian-zhao WANG Lin 
Background During the process of bone cement joint replacement, some patients show a series of complications, such as a sudden drop in blood pressure or dyspnea. The cause of the complication is considered to be due t...
关键词:RADIOIMMUNOIMAGING TRACER bone cement THROMBOSIS PATHOLOGY 
Studies on the Distribution and Radioimmunoimaging of ^(99m)Tc-Labeled 5-Fluorouracil Loaded Immunological Nanoparticles in Tissues and Human Gastric Carcinoma Xenografts
《Chinese Journal of Clinical Oncology》2007年第5期307-312,共6页Kaihong Huang Jianhua Liu Zhaohua Zhu Xuexian Li Xianping Lu 
the grants as fol-lows:The Problems-Tackling Program in Sci-ence and Technology of Guangzhou City,Chi-na(No.2003 Z 3-E0381);National Foundationof Natural Science,China(No.30670951);Guangdong Foundation of Natural Science,Guangdong,China(No.06021322);TheProblems-Tackling Program in Science andTechnology of Guangdong Province,China(No.2005 B31211002).
OBJECTIVE To explore the method of preparation of 99m↑Tc labeled AntiVEGF McAb 5-FU loaded polylactic acid nanoparticles (99m↑TC-5-FU-Ab-NPs), and investigate the biological distribution of the nanoparticles in hu...
关键词:radionuclide imaging gastric carcinoma monoclonal antibody NANOPARTICLES 
Construction of Human ScFv Phage Display Library against Ovarian Tumor被引量:1
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2006年第5期497-499,共3页夏劲松 毕昊 姚琴 屈伸 宗义强 
This project was supported by a grant from the National Natural Sciences Foundation of China (No. 30200295).
In order to construct a single chain fragment variable (ScFv) phage display library against ovarian tumor, by using RT-PCR, the human heavy chain variable region genes (VH) and light chain variable region genes ...
关键词:ScFv phage display library ovarian tumor SOE RADIOIMMUNOIMAGING 
Avidin-biotin system pretargeting radioimmunoimaging and radioimmunotherapy and its application in mouse model of human colon carcinoma被引量:5
《World Journal of Gastroenterology》2005年第40期6288-6294,共7页Gui-Ping Li Hui Zhang Cheng-Mo Zhu, Jian Zhang Xu-Feng Jiang 
AIM: To evaluate the multi-step pretargeting radioimmunoimaging (RII) and radioimmunotherapy (RTT) in nude mice bearing human colon carcinoma with avidin-biotin system labeled with 153^Sm. METHODS: Two- and thre...
关键词:RADIOIMMUNOIMAGING RADIOIMMUNOTHERAPY Avidin-biotin Colon carcinoma 
Clinical application of radioimmunoi maging with (99)~m Tc-BDI-1in the diagnosis of bladder cancer被引量:5
《Chinese Medical Journal》2000年第5期12-15,共4页王荣福 张春丽 
To evaluate the clinical application of radioimmunoimaging (Rll ) with 99m Tc-BDI-1 in thediagnosis of bladder cancer. Methods 32 pstients with bladder cancer and 5 with normal bladder were studied. Rll was...
关键词:radioimmunoimaging · bladder neoplasms  · antibody MONOCLONAL 
Direct technetium-99m labeling of anti-hepatoma monoclonal antibody fragment:a radioimmunoconjugate for hepatocellular carcinoma imaging被引量:13
《World Journal of Gastroenterology》2000年第3期348-352,共5页Hui Jie Bian Zhi Nan Chen Jing Lan Deng 
National Natural Science Foundation of China,No.39700175
AIM To directly radiolabel an anti-hepatomamAb fragment HAb18 F(ab’)2 with 99mTc bystannous-reduced method,and assess thestability,biodistribution and radioimmun-oimaging(RⅡ).METHODS Immuno...
关键词:ANTIBODY MONOCLONAL ANTIBODY FRAGMENTS technetium-99m hepatocellular carcinoma liver neoplasms RADIOIMMUNOIMAGING 
Tumor radioimmunoimaging of chimeric antibody in nude mice with hepatoma xenograft被引量:3
《World Journal of Gastroenterology》1998年第1期12-14,共3页GONG Yi LIU Kang-Da ZHOU Ge XUE Qiong CHEN Shao-Liang TANG Zhao-You 
IM To study the radioimmunoimaging (RAII) using the human/mouse chimeric Ab to evaluate its targeting activity in animal models.METHODS To chimeric Ab was labeled with 131I. RAII was performed at different intervals...
关键词:liver neoplasms  experimental carcinoma  hepatocellular chimeric antibody mice  nude hepatitis B virus disease models  animal RADIOIMMUNODETECTION RADIOIMMUNOTHERAPY 
Radioimmunoimaging of colorectal cancer using ^(99m)Tc-labeled monoclonal antibody被引量:4
《World Journal of Gastroenterology》1998年第4期31-34,共4页HU JinYue1, SU JianZhi2, PI ZhiMing3, ZHU JianGao1, ZHOU GuoHua1 and SUN QuBing1Keywords colorectal neoplasms/radioimmunoimaging antibody, monoclonal isotope labeling technium/diagnostic use 
AIM To determine whether Hb3 and its fragment F(ab')2 have practical value in radioimmunoimaging of colorectal cancer.METHODS Intact Hb3 was purified by hydroxylapatite chromatography. The fragment F(ab')2 was prepare...
关键词:COLORECTAL MONOCLONAL labeled 
RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES
《Chinese Medical Sciences Journal》1997年第2期80-83,共4页孙强 王树蕙 黄汉源 杨子毅 朱预 
In this study, the human breast cancer-bearing nude mice model has been established and the radioim-munoimaging was carried out by using human anti-human monoclonal antibodies. The results showed that the breast tumor...
关键词:breast cancer  human anti-human antibodies RADIOIMMUNOIMAGING 
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