云南高校图书馆联盟文献共享服务平台- SOLASODINE

SOLASODINE: 作品数：13被引量：10H指数：2; 导出分析报告; 相关领域：医药卫生理学更多>>; 相关作者：高培君丁丹郭凤英田伟生况丽琴更多>>; 相关机构：华东理工大学中国科学院更多>>; 相关期刊：《Science China Chemistry》《中国药理学通报》《Modern Chemotherapy》《Chinese Chemical Letters》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划更多>>

The Value of Excipients and the Required Understanding of the Biological System in Product Development: An Impactful Example of Curaderm, a Topical Skin Cancer Treatment: 《International Journal of Clinical Medicine》2024年第2期68-87,共20页Tania Robyn Chase Kai Elliot Cham Bill Elliot Cham; The incidences of nonmelanoma skin cancer are increasing worldwide, and the ongoing war on its treatment necessitates the development of effective and non-invasive methods. Through basic and clinical research, non-inv...; 关键词：Curaderm BEC Solasodine Glycosides SOLAMARGINE Apoptosis Skin Cancer Actinic Keratosis KERATOACANTHOMA Basal Cell Carcinoma Squamous Cell Carcinoma

First in Man Topical Treatment of Melanoma with Solasodine Glycosides in a Formulation Curaderm: A Case Report被引量：1: 《Journal of Cancer Therapy》2020年第10期617-630,共14页B. E. Cham; Background: There is ample evidence to support the safety and efficacy of the topical anticance...; 关键词：MELANOMA Curaderm BEC SOLAMARGINE Non-Melanoma Skin Cancer METASTASIS

Solasodine Glycosides from the Eggplant in a Topical Cream PsorendBECAre Effective against Psoriasis: 《International Journal of Clinical Medicine》2019年第3期174-182,共9页Tania R. Chase Kai E. Cham Bill E. Cham; Background: Psoriasis is a chronic disease that can have significant effects on quality of life. Aim: To test whether the antineoplastic, antipathogenic plant derived secondary metabolites, solasodine glycosides, can ...; 关键词：PSORIASIS BEC SOLASODINE GLYCOSIDES PsorendBEC EGGPLANT Devil’s Apple Black Nightshade

Solasodine, Solamargine and Mixtures of Solasodine Rhamnosides: Pathway to Expansive Clinical Anticancer Therapies: 《International Journal of Clinical Medicine》2017年第12期692-713,共22页Bill E. Cham; Cancer remains a major cause of mortality worldwide. Progresses have been made in the understanding of the molecular basis of cancer, cancer detection, and cancer treatment. Important strides by treating early-stage c...; 关键词：Cancer BEC SOLAMARGINE Apoptosis MDR METASTASIS Curaderm

Solasodine induces apoptosis and inhibits metastasis on ovarian cancer HEY cells: 《中国药理学通报》2015年第B11期240-240,共1页; Aim Solasodine, a steroidal alkaloid isolated from solanaceous species, has been reported to exhibit anticancer activity on several cell lines. The aim of this study is to explore the antitumor potential of solasodine...; 关键词：OVARIAN cancer SOLASODINE APOPTOSIS autophagy migration INVASION

Treatment of Skin Cancer with a Selective Apoptotic-Inducing CuradermBEC5Topical Cream Containing Solasodine Rhamnosides: 《International Journal of Clinical Medicine》2015年第5期326-333,共8页Aruba Cham Bill Cham; Solasodine rhamnosides produced in plants as secondary metabolites, are safe and effective when treating a variety of cancers, including non-melanoma skin cancers. They are cytotoxic against multi-drug resistant tumor...; 关键词：Skin Cancer BEC SOLAMARGINE Curaderm Apoptosis SOLASODINE Rhamnosides

Drug therapy: Solamargine and other solasodine rhamnosyl glycosides as anticancer agents: 《Modern Chemotherapy》2013年第2期33-49,共17页Bill E. Cham; In the last century, the discovery of cytotoxic agents was revolutionary for anticancer therapy. These therapies have resulted in better understanding of cancer in general. However, the development of agents that comb...; 关键词：CANCER Skin CANCER SOLAMARGINE Solasonine BEC SOLASODINE Rhamnosyl GLYCOSIDES CuradermBEC5 Apoptosis ANTINEOPLASTIC Targeted Therapy

Solasodine Glycosides: A Topical Therapy for Actinic Keratosis. A Single-Blind, Randomized, Placebo-Controlled, Parallel Group Study with CuradermBEC5被引量：3: 《Journal of Cancer Therapy》2013年第2期588-596,共9页Bill E. Cham; Background: Untreated actinic keratosis can advance to squamous cell carcinoma, which in turn is associated with a risk of metastasis. Current treatments for actinic keratosis have many shortcomings. This communicatio...; 关键词：SOLASODINE GLYCOSIDES SOLAMARGINE Solasonine Actinic KERATOSIS Apoptosis Skin Cancer Clinical Trial CuradermBEC5

An alternative total synthesis of solamargine: 《Science China Chemistry》2012年第7期1247-1251,共5页WEI GuoHua WEI DongBin DU YuGuo; supported partially by the National Basic Research Program of China (2011CB936001);National Natural Science Foundation of China (20732001,20872172,21072217); Solamargine, （25R）-3β-（O-a-L-rhamnopyranosyl-（1--2）-[O-a-L-rhamnopyranosyl-（1--4）]-β-D-glucopyranosloxy}-22a-N- spirosol-5-ene, isolated from the berries of solanum aculeastrum, has been synthesized in 26.8% ...; 关键词：SOLASODINE natural products SOLAMARGINE GLYCOSIDES

Intralesion and CuradermBEC5Topical Combination Therapies of Solasodine Rhamnosyl Glycosides Derived from the Eggplant or Devil’s Apple Result in Rapid Removal of Large Skin Cancers. Methods of Treatment Compared被引量：8: 《International Journal of Clinical Medicine》2012年第2期115-124,共10页Bill E. Cham; Solasodine rhamnosyl glycosides (SRGs) are chemotherapeutic agents for the treatment of cancer. SRGs in a cream formulation, CuradermBEC5, is very effective for the treatment of nonmelanoma skin cancers with excellent...; 关键词：Cancer Devil’s APPLE EGGPLANT Curaderm SOLAMARGINE Apoptosis

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