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hUCMSC-derived extracellular vesicles relieve cisplatin-induced granulosa cell apoptosis in mice by transferring antiapoptotic miRNAs: 《Journal of Biomedical Research》2025年第1期36-49,共14页Wenjing Tang Haiyan Yan Xiaojun Chen Yanan Pu Xin Qi Liyang Dong Chuan Su; Financial support for the current study was provided by the grant from"Blue Engineering"Excellent Young Teacher Foundation in Colleges and Universities of Jiangsu Province(Grant No.KY101R202207 to Xiaojun Chen)。; Premature ovarian insufficiency(POI)caused by chemotherapy is a common complication in female cancer survivors of childbearing age.Traditional methods,including mesenchymal stem cell(MSC)transplant and hormone replace...; 关键词：CHEMOTHERAPY fertility preservation extracellular vesicles granulosa cell apoptosis microRNAs

Beyond boundaries:Neuroprotective effects of steroids and ecdysteroids in SH-SY5Y cells-A systematic review: 《Neuroprotection》2024年第2期151-166,共16页Bizhar Ahmed Tayeb Isaac Kinyua Njangiru Renata Minorics; Stipendium Hungaricum Scholarship founded by the Hungarian Government。; Steroids and ecdysteroids have been shown to exhibit a range of biological effects,including anti-inflammatory,anticancer,and neuroprotective.This systematic review aims to highlight the evidence-based neuroprotective...; 关键词：ANTIAPOPTOTIC CYTOPROTECTIVE NEUROBLASTOMA NEUROSTEROIDS oxidative stress SH-SY5Y cells

PGRN exacerbates the progression of non-small cell lung cancer via PI3K/AKT/Bcl-2 antiapoptotic signaling被引量：7: 《Genes & Diseases》2022年第6期1650-1661,共12页Sicheng Chen Mengjun Bie Xiaowen Wang Mengtian Fan Bin Chen Qiong Shi Yingjiu Jiang; This research was supported by Chongqing Technology Innovation and application development special fund(No.cstc2019jscx-msxmX0095);National Natural Science Foundation of China(No.NSFC 81672103);The authors are responsible for the results and opinions provided by this research,and the sponsor is not responsible for the content published.; Progranulin(PGRN)is a growth factor that is involved in the progression of multiple tumors.However,the effects and molecular mechanisms by which PGRN induces lung cancer remain unclear.The expression level of PGRN was...; 关键词：BCL-2 Cell apoptosis NSCLC PGRN PI3K/AKT

Antioxidant and Antiapoptotic Polyphenols from Green Tea Extract Ameliorate CCl4-Induced Acute Liver Injury in Mice被引量：7: 《Chinese Journal of Integrative Medicine》2020年第10期736-744,共9页DIAO Jian-xin OU Jin-ying DAI Huan LI Hai-ye HUANG Wei HUA He-yu XIE Ting WANG Ming YANG Yun-gao; Supported by the National Natural Science Foundation of China(No.81673820,81603606,and 81229003);the Guangdong Provinee StudentsTnnovation and Entrepreneurship Training Program(No.3121103018)。; Objective To investigate the phenolic composition,antioxidant properties,and hepatoprotective mechanisms of polyphenols from green tea extract(GTP)in carbon tetrachloride(CCl4)-induced acute liver injury mouse model.M...; 关键词：POLYPHENOL carbon tetrachloride acute liver injury ANTI-OXIDANT ANTI-APOPTOSIS green tea

Melatonin for the treatment of spinal cord injury被引量：5: 《Neural Regeneration Research》2018年第10期1685-1692,共8页Yan Zhang Wen-Xiu Zhang Yan-Jun Zhang Ya-Dong Liu Zong-Jian Liu Qi-Chao Wu Yun Guan Xue-Ming Chen; supported by the National Natural Science Foundation of China,No.81671161(to ZJL); Spinal cord injury（SCI） from trauma or disease severely impairs sensory and motor function. Neurorehabilitation after SCI is a complex medical process that focuses on improving neurologic function and repairing dama...; 关键词：spinal cord injury melatonin secondary damage NEUROPROTECTION antioxidative antiapoptotic ANTI-INFLAMMATORY synergistic effects neural regeneration

Antioxidative and antiapoptotic effects of （＋）-clausenamide on acetaminophen-induced nephrotoxicity in mice: 《TMR Modern Herbal Medicine》2018年第3期127-135,共9页Hong-Min Yu Min Wang Zong-Chao Yu Yi-Fang Li Chun-Xin Huang Fang-Xuan Han Fan-Na Liu Rong-Rong He; This work was partly supported by TCM Modernization Program of Hainan Province （2015ZY01）, Natural Science Foundation of China （81573675 ＆ 81622050 ＆ 81673709）, Science and Technology Program of Guangzhou （201604046016 ＆ 201604020175） and Research Project of Guangdong Provincial Bureau of Traditional Chinese Medicine （20161070）.; Objective：（＋）-Clausenamide （（＋）-CLA）, the active ingredient of wampee, was isolated from the leaves of Clausena lansium （Lour.） Skeels. This study aimed to evaluate the protective potential of ...; 关键词：（＋）-Clausenamide ACETAMINOPHEN Kidney injury Oxidative stress Apoptosis pathway

A Review on Survivin as a Prognostic and Therapeutic Cancer Biomarker被引量：1: 《Open Journal of Pathology》2018年第1期15-23,共9页Amal Ahmed Ismail; Survivin is an antiapoptotic protein expressed in tumor cells that correlates with aggressiveness, prognosis and treatment. Objective: This review summarizes significance of survivin expression among different tumor t...; 关键词：SURVIVIN PROGNOSTIC BIOMARKER Cancer ANTIAPOPTOTIC

Antiapoptotic Effect of Gene Therapy with Recombinant Adenovirus Vector Containing Hypoxia-inducible Factor-1α after Cerebral Ischemia and Reperfusion in Rats被引量：9: 《Chinese Medical Journal》2017年第14期1700-1706,共7页Ming-Lang Yang Tao Tao Jian Xu Zhi Liu Dan Xu; Background：Mounting evidence has demonstrated that hypoxia-inducible factor-1α （HIF-1α） could attenuate brain injuries after cerebral ischemia and reperfusion （CIR）.However,few reports have addressed the therap...; 关键词：APOPTOSIS Cerebral Ischemia Hypoxia-inducible Factor-1 α Recombinant Adenovirus Vector REPERFUSION

Antiapoptotic activity of 30 kDa lipoproteins family from fat body tissue of silkworm, Bombyx moil: 《Insect Science》2015年第5期629-638,共10页Britto Cathrin Pakkianathan Nitin Kumar Singh Simone Konig Muthukalingan Krishnan; The family of 30kDa lipoproteins （LP1-5） is abundant in silkworm pupa fat body （FB） and hemolymph. One of its members, the 29 kDa protein decreased in concentration from peripheral （PP） FB tissue but was sustain...; 关键词：actinomycin D apoptosis Bombyx mori fat body tissue 30 kDa proteins

Amentoflavone protects hippocampal neurons: anti-inflammatory, antioxidative, and antiapoptotic effects被引量：11: 《Neural Regeneration Research》2015年第7期1125-1133,共9页Zhen Zhang Tao Sun Jian-guo Niu Zhen-quan He Yang Liu Feng Wang; supported by the National Natural Science Foundation of China,No.81460208;the Ningxia Natural Science Foundation of China,No.NZ13163; Amentoflavone is a natural biflavone compound with many biological properties, including anti-inflammatory, antioxidative, and neuroprotective effects. We presumed that amentoflavone exerts a neuroprotective effect in...; 关键词：nerve regeneration brain injury epilepsy neuroprotection apoptosis nuclear factor-κB brain inflammation interleukin-6 interleukin-1 beta inducible nitric oxide synthase nitric oxide prostaglandin E2 NSFC grant neural regeneration

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