COEXPRESSION

作品数：35被引量：87H指数：5
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Comparative transcriptome sequencing and weighted coexpression network analysis reveal growth-related hub genes and key pathways in the Chinese soft-shelled turtle(Pelodiscus sinensis)
《Water Biology and Security》2024年第4期65-76,共12页Guobin Chen Tong Zhou Jizeng Cao Guiwei Zou Hongwei Liang 
supported by the National Natural Science Foundation of China(32302992);the Central Public-Interest Scientific Institution Basal Research Fund;CAFS(No.2023TD36 and YFI202406);the National Freshwater Aquatic Germplasm Resource Center(FGRC18537).
The Chinese soft-shelled turtle(Pelodiscus sinensis)exhibits sexual dimorphism.Compared with females,males are considered to have higher economic value due to their accelerated growth,greater body mass,and longer skir...
关键词：Growth Sexual dimorphism Pelodiscus sinensis Comparative transcriptome sequencing 
Salivary metabolites are promising noninvasive biomarkers of druginduced liver injury
《World Journal of Gastroenterology》2024年第18期2454-2466,共13页Si-Miao Yu Hao-Cheng Zheng Si-Ci Wang Wen-Ya Rong Ping Li Jing Jing Ting-Ting He Jia-Hui Li Xia Ding Rui-Lin Wang 
Supported by Medical Education Association Foundation of China,No.2020KTY001;National Natural Science Foundation of China,No.81673806;National Natural Science Foundation Youth Fund,No.82104702.
BACKGROUND Drug-induced liver injury(DILI)is one of the most common adverse events of medication use,and its incidence is increasing.However,early detection of DILI is a crucial challenge due to a lack of biomarkers a...
关键词：Drug-Induced liver injury SALIVARY Metabolomics BIOMARKER Weighted metabolite Coexpression network analysis Machine learning NONINVASIVE Diagnostic method METABOLITES 
Lipase and photodecarboxylase coexpression: A potential strategy for alkane-based biodiesel production from natural triglycerides
《Chinese Journal of Chemical Engineering》2024年第3期238-246,共9页Yong-Yi Zeng Xin-Yi Xu Jin-Xuan Xie Wen-Li Chen Lan Liu Xin-Jian Yin Bi-Shuang Chen 
financially supported by the National Natural Science Foundation of China(42376097);Guangdong Basic and Applied Basic Research Foundation(2023A1515030226,2021A1515010829).
Alkane-based biodiesel is considered the next generation of biodiesel owing to its potential environmental benefits and the fact that it exhibits much higher specific caloric values than traditional biodiesel.However,...
关键词：Alkane-based biodiesel Renewable biomass Co-overexpression LIPASE Photodecarboxylase 
Identification of immune cell-related prognostic genes characterized by a distinct microenvironment in hepatocellular carcinoma
《World Journal of Clinical Oncology》2024年第2期243-270,共28页Meng-Ting Li Kai-Feng Zheng Yi-Er Qiu 
BACKGROUND The development and progression of hepatocellular carcinoma(HCC)have been reported to be associated with immune-related genes and the tumor microenvir-onment.Nevertheless,there are not enough prognostic bio...
关键词：Hepatocellular carcinoma Prognostic model Weighted gene coexpression network analysis MICROENVIRONMENT CHEMOTHERAPY 
Transcriptome-based analysis of key genes and pathways affecting the linoleic acid content in chickens
《Journal of Integrative Agriculture》2023年第12期3744-3754,共11页ZHAO Wen-juan YUAN Xiao-ya XIANG Hai MA Zheng CUI Huan-xian LI Hua ZHAO Gui-ping 
This study was supported by the China Agriculture Research System of MOF and MARA(CARS-41);the Key-Area Research and Development Program of Guangdong Province,China(2020B020222002);the Foshan University High-level Talent Program,China(CGZ07243);the Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding,China(2019B030301010);the Key Laboratory of Animal Molecular Design and Precise Breeding of Guangdong Higher Education Institutes,China(2019KSYS011);the Foshan Institute of Science and Technology Postgraduate Free Exploration Fund,China(2021ZYTS36).
Linoleic acid is an essential polyunsaturated fatty acid that cannot be synthesized by humans or animals themselves and can only be obtained externally.The amount of linoleic acid present has an impact on the quality ...
关键词：CHICKEN linoleic acid transcriptome sequencing weighted gene coexpression network analysis(WGCNA) metabolic pathways 
Establishment of a prognostic model related to tregs and natural killer cells infiltration in bladder cancer
《World Journal of Clinical Cases》2023年第15期3444-3456,共13页Yan-Jie Yang Xiao-Qing Xu Yi-Chao Zhang Peng-Cheng Hu Wu-Xia Yang 
BACKGROUND Regulatory T cells(Tregs)and natural killer(NK)cells play an essential role in the development of bladder urothelial carcinoma(BUC).AIM To construct a prognosis-related model to judge the prognosis of patie...
关键词：Natural killer cells TREGS Bladder cancer Weighted gene coexpression network analysis Bladder cancer treatment IMMUNOTHERAPY Computational molecular biology 
A Naive Bayes model on lung adenocarcinoma projection based on tumor microenvironment and weighted gene coexpression network analysis
《Infectious Disease Modelling》2022年第3期498-509,共12页Zhiqiang Ye Pingping Song Degao Zheng Xu Zhang Jianhong Wu 
Our deepest gratitude goes to the editors and anonymous reviewers for their careful work and thoughtful suggestions that have helped to improve this paper substantially.The workwas supported by the National Natural Science Foundation of China(No.12071382);the Bowang scholar youth talent program(Zhiqiang Ye)of Chongqing Normal University,the Natural Science and Engineering Research Council of Canada,and the Canada Research Chair Program(JWu).
Based on the lung adenocarcinoma(LUAD)gene expression data from the cancer genome atlas(TCGA)database,the Stromal score,Immune score and Estimate score in tumor microenvironment(TME)were computed by the Estimation of ...
关键词：Naive Bayes model Tumor microenvironment Lung adenocarcinoma Weighted gene co-expression network ANALYSIS Prognostic biomarkers 
Coexpression of TLR9 and VEGF-C is associated with lymphatic metastasis in prostate cancer
《Asian Journal of Andrology》2022年第4期380-385,共6页Xian-Zi Zeng Zhan-Sen Huang Hong-Peng Fang Jie-Ying Wu Qun-Xiong Huang Chu-Bin Zhuang Jing Zhou Jin-Ming Di 
supported by grants from the Natural Science Foundation of Guangdong Province(No.2018A030313261 and No.2021Al515010129);Guangdong Medical Science and Technology Research Foundation(No.A2018079);the National Natural Science Foundation of China(No.81772752).
Prostate cancer(PCa)is one of the most frequent cancers in men,and its biomolecular targets have been extensively studied.This study aimed to analyze the expression of toll-like receptor 9(TLR9)and vascular endothelia...
关键词：biochemical progression-free survival COEXPRESSION lymphatic metastasis prostate cancer toll-like receptor 9 vascular endothelial growth factor C 
Improved pinene production in a recombinant yeast by fusion linker optimization and chaperon coexpression被引量：1
《Systems Microbiology and Biomanufacturing》2022年第1期208-216,共9页Quanlu Ren Yaxi He Xinyao Lu Hong Zong Bin Zhuge 
This work was supported by the National Natural Science Foundation of China(No.31970033).
Pinene is an active natural monoterpene from plants and has important applications in favorings,fragrances,and pesticides.Especially,pinene dimers are regarded as renewable fuels with high density.However,the microbia...
关键词：PINENE Saccharomyces cerevisiae Fusion protein Oligopeptide linker CHAPERONES 
Identification of key genes affecting porcine fat deposition based on coexpression network analysis of weighted genes被引量：5
《Journal of Animal Science and Biotechnology》2022年第1期36-51,共16页Kai Xing Huatao Liu Fengxia Zhang Yibing Liu Yong Shi Xiangdong Ding Chuduan Wang 
financially supported by the National Key Research and Development Project(2019YFE0106800);the National Key R&D Program of China(2018YFD0501000);Beijing Municipal Education Commission Science and Technology Program General Project(KM201910020010);Beijing Innovation Consortium of Agriculture Research System(BAIC02-2021);the China Agriculture Research System(CARS-35).
Background:Fat deposition is an important economic consideration in pig production.The amount of fat deposition in pigs seriously affects production efficiency,quality,and reproductive performance,while also affecting...
关键词：Fat deposition PIGS RNA-SEQ WGCNA 
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