Funded by the National Natural Science Foundation of China(No.81201386);the China Postdoctoral Science Foundation(No.20100470110)
In order to look for the best proportion of β-tricalcium phosphate(β-TCP)and poly(lactideco-glycolide)(PLGA)we fabricated porous composites β-TCP/PLGA scaffold using freeze-drying method.Morphologicalcharacte...
Funded by the "973" Chinese National Key Fundamental Research and Development Program (No.G1999064701);the Research Fund of Key Laboratory for Advanced Technology in Environmental Protection of Jiangsu Province (AE201037)
β-TCP ceramics drug carrier was first prepared and characterized. SEM showed that β-TCP carrier was in porous amorphous structure with diameters around 10 μm. The physical properties including apparent porosity, vo...
National Natural Science Foundation of China(No.81190133);Self-Determined and Innovation Research Funds of WUT(No.2012-IV-069)
To investigate the molecular aspects of osteoblastic interactions with β tricalcium phosphate (β-TCP) particles, human osteoblast-like MG-63 cells were cultured with β-TCP particles at a density of 6 mg/mL cultur...
the Research Fund of Key Labortary for Advanced Technology in Environmental Protection of Jiangsu Province (No. AE201037);the Foundation for Talent Recruitment of Yancheng Institute of Technology (No. XKR2011007);the "973" Chinese National Key Fundamental Research and Development Program (No. G1999064701)
After co-cultrured osteoblast with fl-TCP ceramics, the cellular proliferating, mineralization and osteocalcin expression were studied. MTT assay showed that fl-TCP ceramics had no affect on cellular proliferating. La...
Funded by the Research Fund of Key Laboratory for Advanced Technology in Environmental Protection of Jiangsu Province (AE201037);the Foundation for Talent Recruitment of Yancheng Institute of Technology (XKR2011007);"973" Chinese National Key Fundamental Research and Development Program (No.G1999064701)
β-TCP, as one of calcium phosphates ceramics, exerts perfect biocompatibility and osteoconductivity, and is clinically used as a bone graft substitute for decades. Consequently, the effects of β-TCP ceramics on intr...
Funded by the Funds from Science and Technology Commission of Shanghai Municipality(0852nm05200)
The freeze-extraction and freeze-gelation methods were used to prepare highly porous β-TCP/CS scaffolds with different β-TCP/CS ratio.In these methods,the suspending mixture of β-TCP and chitosan was frozen,the fro...
PDLLA/CHI/β-TCP/NGF composite films were prepared by a solvent evaporation method. The degradation characteristics of the poly (d, l-lactide) composite films were studied in vitro and in vivo. The acidity produced ...
Funded by the "973" Chinese National Key Fundamental Research and Development Program (No.G1999064701);Key Technologies R&D Program of Hubei Province (No.2004AA303B03)
The osteoblast with the β-TCP ceramic was co-cultured. Scanning electron microscopy shows the cells adhered onto β-TCP ceramic surface and grew better, proving the β-TCP ceramic has a biocompatible property. The Co...
The purpose of this study is to explore the feasibility of repairing mandibular defect with osteoconductive porous beta-tricalcium phosphate ( β- TCP ) combined with osteoinductive bone matrix gelatin ( BMG ), wh...
Calcium-phosphate materials, such as β- TCP could be degraded in vivo , and in the cultured cells in vitro. However , it is still unknown how the materials changed the activity of the cells. In order to understand th...