PARKINSONS_DISEASE

作品数：727被引量：1588H指数：17
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《Silver Bullet of Acidification》: Studying Anti-PD Neuroprotective Mechanisms of Transient pH-Decrease
《BIOCELL》2025年第3期451-464,共14页Kristina A.Kritskaya Evgeniya I.Fedotova Alexander D.Nadeev Alexey V.Berezhnov 
supported by the Ministry of Science and Higher Education of the Russian Federation in the Framework of State Assignment of PSCBR RAS 075-00609-24-01(No.1022080100047-5-1.6.4,Neuroprotective drugs of a new generation).
Objective:Activation of mitophagy is a promising option to overcome the mitochondrial malfunction that accompanies many diseases.Herein,we investigate the mechanisms underlying the ability of sodium lactate and pyruva...
关键词：Parkinson’s disease mitochondrial network MITOPHAGY FIBROBLASTS 
Unraveling the molecular crossroads:T2DM and Parkinson’s disease interactions
《BIOCELL》2024年第12期1735-1749,共15页TINGTING LIU XIANGRUI KONG JIANSHE WEI 
supported partly by National Natural Science Foundation of China(32161143021,81271410);Henan University Graduate«Talent Program»of Henan Province(SYLYC2023092);Henan Natural Science Foundation of China(182300410313).
Type 2 diabetes mellitus(T2DM)is a chronic metabolic disorder characterized by persistent hyperglycemia.In recent times,an elevated risk of Parkinson’s disease(PD)development among individuals with T2DM has become ev...
关键词：Type 2 diabetes mellitus Parkinson’s disease Oxidative stress Mitochondrial dysfunction AUTOPHAGY 
Pioneering a new era in Parkinson’s disease management through adipose-derived mesenchymal stem cell therapy
《BIOCELL》2024年第10期1419-1428,共10页MOHAMMAD-SADEGH LOTFI FATEMEH B.RASSOULI 
Parkinson’s disease(PD)is one of the fastest-growing neurodegenerative disorders worldwide.So far,PD treatments only offer little clinical relief and cannot reverse or stop the disease progression.Stem cell(SC)therap...
关键词：Parkinson’s disease Adipose derived-mesenchymal stem cells Cell therapy Dopaminergic neurons 
The pathogenesis of Parkinson’s disease and crosstalk with other diseases被引量：1
《BIOCELL》2024年第8期1155-1179,共25页TINGTING LIU DINGYOU GUO JIANSHE WEI 
supported partly by the National Natural Science Foundation of China(32161143021,81271410);Henan University Graduate《Talent Program》of Henan Province(SYLYC2023092);Henan Natural Science Foundation of China(182300410313).
In China,Parkinson’s disease(PD)is the second most prevalent central nervous system(CNS)degenerative illness affecting middle-aged and older persons.Movement disorders including resting tremor,bradykinesia,myotonia,p...
关键词：Parkinson’s disease Mitochondrial dysfunction Oxidative stress Inflammation Cancer THERAPIES 
Exercise and exerkine upregulation:Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease
《BIOCELL》2024年第5期693-706,共14页VIRAAJ VISHNU PRASAD JENNIFER SALLY SAMSON VENKATACHALAM DEEPA PARVATHI 
Physical activity and exercise have several beneficial roles in enhancing both physiological and psychological well-being of an individual.In addition to aiding the regulation of aerobic and anaerobic metabolism,exerc...
关键词：Exercise therapy Dopaminergic neurons Parkinson’s disease Brain-derived neurotrophic factor Electrical stimulation 
Pathogenic genes associated with Parkinson’s disease:molecular mechanism overview
《BIOCELL》2024年第5期707-729,共23页TINGTING LIU YIWEI HAO LIFENG ZHAO 
supported partly by Henan University graduate“Talent Program”of Henan Province(SYLYC2023092).
Parkinson’s disease(PD)is a common neurodegenerative disease in the elderly,accounting for more than 1%of the population aged 65 years.Monogenic inheritance is relatively rare in PD,accounting for approximately 5%to ...
关键词：Parkinson’s disease(PD) Molecular genetics MUTATION 
Pharmacotherapeutics and molecular docking studies of alphasynuclein modulators as promising therapeutics for Parkinson’s disease被引量：2
《BIOCELL》2022年第12期2681-2694,共14页RAHAT ALI AFTAB ALAM SATYENDRA K.RAJPUT RAZI AHMAD 
Parkinson’s disease(PD)is an age-related neurodegenerative ailment that affects dopamine-producing neurons in a specific area of the brain called the substantia nigra of the ventral midbrain.It is clinically characte...
关键词：Parkinson’s disease(PD) ALPHA-SYNUCLEIN Molecular docking and dynamics Anti-Parkinson drug Curcumin PIPERINE 
Potential roles of functional bacterial amyloid proteins,bacterial biosurfactants and other putative gut microbiota products in the etiopathogeny of Parkinson’s Disease被引量：3
《BIOCELL》2021年第1期1-16,共16页EMILIA MANOLE LAURA DUMITRESCU CRISTINA NICULIȚE BOGDAN OVIDIU POPESCU LAURA CRISTINA CEAFALAN 
was supported by the Ministry of Research and Innovation in Romania,under Grants No.PN 1N/2019_19.29.02.01,No.7PFE/2018.
An increasing number of studies provide evidence for the existence of a microbiota-gut-brain axis and its potential involvement in the development of sporadic Parkinson’s disease and other neurodegenerative condition...
关键词：ALPHA-SYNUCLEIN ENDOTOXINS Short-chain fatty acids 
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