the National Key Research and Development Program of China(2016YFC1306600);the National Natural Science Foundation of China(82001483);the Guangdong Provincial Key R&D Program(2018B030337001).
Parkinson’s disease(PD),the second most common neurodegenerative disease,is clinically characterized by both motor and non-motor symptoms.Although overall great achievements have been made in elucidating the etiology...
the National Science Foundation of China(81601098 and 81603181);the Natural Science Foundation of Jiangsu Province(BK20150302,BK20170004);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(19KJB310016);Suzhou Science and Technology for People's Livelihood(SYS201706);the Natural Science Foundation of Suzhou(SYSD2018099).
Patients with diabetes mellitus have a higher risk of developing Parkinson’s disease(PD). However, the molecular links between PD and diabetes remain unclear.In this study, we investigated the roles of thioredoxinint...
supported in part by the National Natural Science Foundation of China (81471212);the Taishan Scholar Project to BLS
Dear Editor,Parkinson’s disease (PD) is the second most common neurodegenerative disease in the elderly (1, 2)PD affects1%–2%of the world’s population older than 65 years(3–5)In recent years, large-scale genome-wi...
In this review, combined post-mortem brain magnetic resonance imaging(MRI) and histology studies are highlighted, illustrating the relevance of translational approaches to de?ne novel MRI signatures of neuropathologic...
supported by the Science Technological Project of Shandong Province (2018CXGC1502 and 2016GSF201058);the National Natural Science Foundation of China (31571104 and 81501149)
The thalamostriatal pathway is implicated in Parkinson's disease(PD); however, PD-related changes in the relationship between oscillatory activity in the centromedian-parafascicular complex(CM/Pf, or the Pf in rodents...
Parkinson's disease (PD) neurodegenerative disease is the second most common worldwide. Since its first description as a neurological disorder by James Parkinson (1755-1824) in 1817, many important discoveries ha...
supported by the grants of International Cooperative Key Project of National Natural Science Foundation of China(81520108010);the Natural Science Foundation of Shaoxing Municipality,Zhejiang Province,China(2016QN020)
Exosomes, nano-sized extracellular vesicles secreted by most cell types, are found in all kinds of biological fluids and tissues, including the central nervous system(CNS). The proposed functions of these vesicles i...