PARKINSONS

作品数:206被引量:376H指数:9
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相关领域:医药卫生生物学更多>>
相关作者:王宏梅王奇王奇更多>>
相关机构:辽东学院安徽医科大学广州中医药大学中山大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家高技术研究发展计划更多>>
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Hot Topics in Recent Parkinson’s Disease Research:Where We are and Where We Should Go被引量:5
《Neuroscience Bulletin》2021年第12期1735-1744,共10页Song Li Congcong Jia Tianbai Li Weidong Le 
the National Key Research and Development Program of China(2016YFC1306600);the National Natural Science Foundation of China(82001483);the Guangdong Provincial Key R&D Program(2018B030337001).
Parkinson’s disease(PD),the second most common neurodegenerative disease,is clinically characterized by both motor and non-motor symptoms.Although overall great achievements have been made in elucidating the etiology...
关键词:Parkinson’s disease Gut-brain axis Biomarkers NEUROINFLAMMATION Sleep disorder Genetics Ferroptosis 
Thioredoxin-Interacting Protein(TXNIP) Regulates Parkin/PINK1-mediated Mitophagy in Dopaminergic Neurons Under High-glucose Conditions: Implications for Molecular Links Between Parkinson’s Disease and Diabetes被引量:7
《Neuroscience Bulletin》2020年第4期346-358,共13页Cun-Jin Su Zhu Shen Ru-Xiao Cui Ya Huang De-Lai Xu Feng-Lun Zhao Jie Pan Ai-Ming Shi Tong Liu Yun-Li Yu 
the National Science Foundation of China(81601098 and 81603181);the Natural Science Foundation of Jiangsu Province(BK20150302,BK20170004);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(19KJB310016);Suzhou Science and Technology for People's Livelihood(SYS201706);the Natural Science Foundation of Suzhou(SYSD2018099).
Patients with diabetes mellitus have a higher risk of developing Parkinson’s disease(PD). However, the molecular links between PD and diabetes remain unclear.In this study, we investigated the roles of thioredoxinint...
关键词:DIABETES mellitus Parkinson’s disease High GLUCOSE TXNIP MITOPHAGY PC12 cells 
Parkinson's Disease Risk Variant rs1109303 Regulates the Expression of INPP5K and CRK in Human Brain被引量:1
《Neuroscience Bulletin》2019年第2期365-368,共4页Guiyou Liu Yi Zhao Jing-yi Sun Bao-liang Sun 
supported in part by the National Natural Science Foundation of China (81471212);the Taishan Scholar Project to BLS
Dear Editor,Parkinson’s disease (PD) is the second most common neurodegenerative disease in the elderly (1, 2)PD affects1%–2%of the world’s population older than 65 years(3–5)In recent years, large-scale genome-wi...
关键词:Parkinson’s DISEASE QTL SLC 
Post-Mortem MRI and Histopathology in Neurologic Disease:A Translational Approach被引量:4
《Neuroscience Bulletin》2019年第2期229-243,共15页Laura E.Jonkman Boyd Kenkhuis Jeroen J.G.Geurts Wilma D.J.van de Berg 
In this review, combined post-mortem brain magnetic resonance imaging(MRI) and histology studies are highlighted, illustrating the relevance of translational approaches to de?ne novel MRI signatures of neuropathologic...
关键词:MRI Histology Biomarkers Multiple SCLEROSIS Alzheimer’s DISEASE Parkinson’s DISEASE 
Altered Local Field Potential Relationship Between the Parafascicular Thalamic Nucleus and Dorsal Striatum in Hemiparkinsonian Rats被引量:5
《Neuroscience Bulletin》2019年第2期315-324,共10页Haiyan Zhang Jing Yang Xuenan Wang Xiaomeng Yao Hongyu Han Yunfeng Gao Hongli Chang Tianyu Xiang Shuang Sun Yanan Wang Xiusong Wang Min Wang 
supported by the Science Technological Project of Shandong Province (2018CXGC1502 and 2016GSF201058);the National Natural Science Foundation of China (31571104 and 81501149)
The thalamostriatal pathway is implicated in Parkinson's disease(PD); however, PD-related changes in the relationship between oscillatory activity in the centromedian-parafascicular complex(CM/Pf, or the Pf in rodents...
关键词:Parkinson’s disease Parafascicular THALAMIC NUCLEUS DORSAL STRIATUM Local field potential Synchronization 
Milestones of Parkinson's Disease Research:200 Years of History and Beyond被引量:6
《Neuroscience Bulletin》2017年第5期598-602,共5页Song Li Weidong Le 
Parkinson's disease (PD) neurodegenerative disease is the second most common worldwide. Since its first description as a neurological disorder by James Parkinson (1755-1824) in 1817, many important discoveries ha...
关键词:In Milestones of Parkinson’s Disease Research Years of History and Beyond PD DBS 
Exosomes in Parkinson's Disease被引量:11
《Neuroscience Bulletin》2017年第3期331-338,共8页Xiaoqing Wu Tingting Zheng Baorong Zhang 
supported by the grants of International Cooperative Key Project of National Natural Science Foundation of China(81520108010);the Natural Science Foundation of Shaoxing Municipality,Zhejiang Province,China(2016QN020)
Exosomes, nano-sized extracellular vesicles secreted by most cell types, are found in all kinds of biological fluids and tissues, including the central nervous system(CNS). The proposed functions of these vesicles i...
关键词:Exosomes Parkinson’s disease Biomarker Pathology Therapy 
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