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supported by the National Natural Science Foundation (NSF)of China:JSK (32071137 and 92054103);Funding for Scientific Research and Innovation Team of The First Affliated Hospital of Zhengzhou University:JSK (ZYCXTD2023014)。
Mitochondrial membrane potential(MMP)plays a crucial role in the function of cells and organelles,involving various cellular physiological processes,including energy production,formation of reactive oxygen species(ROS...
This work was supported by the National Natural Science Foundation of China(81671109,82071526,and 82071433);the Natural Science Foundation of Shaanxi Province(2021JQ-417).
L-dopa(l-3,4-dihydroxyphenylalanine)-induced dyskinesia(LID)is a debilitating complication of dopamine replacement therapy for Parkinson’s disease.The potential contribution of striatal D_(2) receptor(D2R)-positive n...
This work was supported by Start-up Funds from Wenzhou Medical University(89211010 and 89212012);the National Natural Science Foundation of China(81630040,31771178,and 81600991);the Natural Science Foundation of Zhejiang Province of China(LY21H090014 and LQ18C090002).
Astrocytes are increasingly recognized to play an active role in learning and memory,but whether neural inputs can trigger event-specific astrocytic Ca^(2+)dynamics in real time to participate in working memory remain...
This work was supported by grants from the National Natural Science Foundation of China(31970953,81930032,and 81760505);the Natural Science Foundation of Jiangxi Province,China(20192ACB21024,20192ACB20023,20181ACG70003,and 20192BCB23008).
Chronic stress leads to many psychiatric disorders,including social and anxiety disorders that are associated with over-activation of neurons in the basolateral amygdala(BLA).However,not all individuals develop psychi...
the National Natural Science Foundation of China(31872771,32070995,and 31900713);the National Demonstration Center for Experimental Basic Medical Science Education(Xuzhou Medical University).
Fiber photometry is a recently-developed method that indirectly measures neural activity by monitoring Ca^(2+)signals in genetically-identified neuronal populations.Although fiber photometry is widely used in neurosci...
This work was supported by a Shenzhen Governmental Grant(JCYJ20180302145710934);the National Natural Science Foundation of China(31700907 and 31700908);the Key-Area Research and Development Program of Guangdong Province(2018B030331001);the International Partnership Program of the Chinese Academy of Sciences(172644KYS820170004);the Strategic Priority Research Program of Chinese Academy of Science(XDB32030100);Guangdong Special Support Program([2018]9);Ten Thousand Talent Program;Key Laboratory of SIAT(2019DP173024);the Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences.
Key requirements of successful animal behavior research in the laboratory are robustness,objectivity,and high throughput,which apply to both the recording and analysis of behavior.Many automatic methods of monitoring ...
the National Natural Science Foundation of China(81701100,81870891,and 81971038);the Fund for Jiangsu Province Specially-Appointed Professor(2016 and 2018);the Natural Science Foundation of Jiangsu Province,China(BK20171160);the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(17KJA320007 and 18KJA320009);the Jiangsu Province Fund for Dominant Discipline(Anesthesiology);Academic Startup Packages from Xuzhou Medical University,China(D2017009 and D2017010)。
Deep brain stimulation of the subthalamic nucleus(STN)is an effective therapy for motor deficits in Parkinson’s disease(PD),but commonly causes weight gain in late-phase PD patients probably by increasing feeding mot...
the Ministry of Science and Technology of China(2012YQ03026005,2013ZX0950910,and2015BAI08B02);the National Natural Science Foundation of China(91432114,91632302);the Beijing Municipal Government
Fiber photometry is a sensitive and easy way to detect changes in fluorescent signals. The combination of fiber photometry with various fluorescent biomarkers has substantially advanced neuroscience research over the ...