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作品数：657被引量：1420H指数：15
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相关机构：第三军医大学西南医院中山大学中国科学院上海市第一人民医院更多>>
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Granulocyte colony-stimulating factor in neutropenia management after CAR-T cell therapy:A safety and efficacy evaluation in refractory/relapsed B-cell acute lymphoblastic leukemia
《Chinese Medical Journal》2025年第1期111-113,共3页Xinping Cao Meng Zhang Ruiting Guo Xiaomei Zhang Rui Sun Xia Xiao Xue Bai Cuicui Lyu Yedi Pu Juanxia Meng Huan Zhang Haibo Zhu Pengjiang Liu Zhao Wang Yu Zhang Wenyi Lu Hairong Lyu Mingfeng Zhao 
supported by grants from the General Project of the National Natural Science Foundation of China(No.81970180);the Science and Technology Project of Tianjin Municipal Health Committee(No.TJWJ2022QN030);the Key projects of Tianjin Applied Basic Research and Multi-Investment Fund(No.21JCZDJC01240);the Science and Technology Project of Tianjin Municipal Health Committee(No.TJWJ2022XK018);Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-056B);Tianjin Municipal Natural Science Foundation(No.22JCQNJC00820);Tianjin Health Research Project(No.TJWJ2023QN027);Tianjin Health Bureau Project(No.ZC20074);Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJWJ2023XK010);Henan Provincial Youth and Middle-aged Health Science and Technology Talents Excellent Youth Program(No.20230273).
To the Editor:After chimeric antigen receptor T(CAR-T)cell therapy,over 90%of patients experience either mild or severe cytopenia,with the prevalence of Grades 3–4 neutropenia ranging from 53%to 94.3%.[1,2]Granulocyt...
关键词：anti inflammatory effects efficacy cytokine release syndrome chimeric antigen receptor T cell therapy NEUTROPENIA granulocyte colony stimulating factor 
An assessment model for efficacy of autologous CD19 chimeric antigen receptor T-cell therapy and relapse or refractory diffuse large B-cell lymphoma risk
《Chinese Medical Journal》2025年第1期108-110,共3页Bin Xue Yifan Liu Min Zhang Gangfeng Xiao Xiu Luo Lili Zhou Shiguang Ye Yan Lu Wenbin Qian Li Wang Ping Li Aibin Liang 
supported by grants from the National Key R&D Program of China(No.2021YFA1100800);National Natural Science Foundation of China(Nos.81830004 and 82070168);Translational Research Grant of NCRCH(No.2020ZKZC04);Shanghai Municipal Health Commission(No.2020CXJQ02);Cultivation project of National Natural Science Foundation of Shanghai Tongji Hospital(No.GJPY2332).
To the Editor:Autologous CD19 chimeric antigen receptor(CAR)T-cell therapy has emerged as a crucial treatment option for patients with relapsed or refractory diffuse large B-cell lymphoma(r/r DLBCL).[1]While CAR-T-cel...
关键词：therapeutic efficacy chimeric antigen REFRACTORY predictive model Chimeric Antigen Receptor T cell therapy diffuse large B cell lymphoma 
Resistance mechanisms and potential therapeutic strategies in relapsed or refractory natural killer/T cell lymphoma
《Chinese Medical Journal》2024年第19期2308-2324,共17页Chengji Wang Liang Wang 
funded by Beijing Physician Scientist Training Project(No.BJPSTP-2024-01)to Liang Wang.
Natural killer/T cell lymphoma(NKTCL)is a malignant tumor originating from NK or T cells,characterized by its highly aggressive and heterogeneous nature.NKTCL is predominantly associated with Epstein-Barr virus infect...
关键词：Natural killer/T cell lymphoma Epstein-Barr virus Chemotherapy resistance ASPARAGINASE IMMUNOTHERAPY 
Ablation of drivers in patients with persistent atrial fibrillation refractory to pulmonary vein antral isolation:Target characteristics and 3-year outcomes
《Chinese Medical Journal》2024年第14期1747-1749,共3页Liang Shi Jie Qi Yanjiang Wang Wenkai Liao Xuexun Li Shunan He Lihong Huang Ying Tian Xingpeng Liu 
supported by grants from the Beijing Natural Science Foundation(No.7202050);the 1315 personal training plan(CYMY-2017-03).
To the Editor:Pulmonary vein antral isolation(PVAI)is the cornerstone of catheter ablation techniques used in the treatment of patients with atrial fibrillation(AF).However,the outcomes of a PVAI-only strategy for per...
关键词：ATRIAL PATIENTS FIBRILLATION 
Safety and efficacy of a novel responsive neurostimulation system in China for drug-refractory focal epilepsy:The first-in-man study被引量：1
《Chinese Medical Journal》2024年第12期1486-1488,共3页Kailiang Wang Yongzhi Shan Penghu Wei Liankun Ren Liang Chen Junming Zhu Guoguang Zhao 
supported by grants from the National Natural Science Foundation of China(Nos.82030037,81801288,and 81871009);STI2030-Major Projects(No.2021ZD0201801);the Translational and Application Project of Brain-inspired and Network Neuroscience on Brain Disorders,Beijing Municipal Health Commission(No.11000022T000000444685)
To the Editor:Recent studies have characterized drugresistant epilepsy(DRE)as essentially a neural network disease.[1]Detection and disconnection of this pathological epileptic connectome or network can greatly improv...
关键词：EPILEPSY STIMULATION DRUG 
Correlation of circulating tumor DNA EGFR mutation levels with clinical outcomes in patients with advanced lung adenocarcinoma
《Chinese Medical Journal》2021年第20期2430-2437,共8页Xiang-Liang Liu Ri-Lan Bai Xiao Chen Yu-Guang Zhao Xu Wang Ke-Wei Ma Hui-Min Tian Fu-Jun Han Zi-Ling Liu Lei Yang Wei Li Fei Gai Jiu-Wei Cui 
supported by the National Key Research&Development Program of China(No.2016YFC1303800);Innovation Project of Health and Technology in Jilin Province(No.2017J064);Special Project of Development and Reform Commission in Jilin Province(No.2017C022);Key Laboratory Construction Project of Department of Science and Technology of Jilin Province(No.20170622011JC)。
Background:Circulating tumor DNA(ctDNA)is a promising biomarker for non-invasive epidermal growth factor receptor mutations(EGFRm)detection in lung cancer patients,but existing methods have limitations in sensitivity ...
关键词：Lung adenocarcinoma Non-small cell lung adenocarcinoma Liquid biopsy Super-amplification-refractory mutation system EGFR mutation 
Refractory hypotension under neuraxial anesthesia for cesarean delivery被引量：1
《Chinese Medical Journal》2019年第12期1509-1511,共3页Shu-Ying Li Xiao-Jing Chen Xue-Mei Lin 
Aortocaval compression syndrome is also known as a supine hypotensive syndrome, it is very common in late pregnancy especially in supine positioning under neuraxial anesthesia. It is occurred when the inferior vena ca...
关键词：REFRACTORY HYPOTENSION neuraxial ANESTHESIA CESAREAN delivery 
Specific White Matter Impairments in Patients with Treatment-Refractory First-Episode Schizophrenia： A 1-Year Follow-up Pilot Study被引量：1
《Chinese Medical Journal》2018年第7期879-880,共2页Min Chen Chuan-Jun ZhUO Li-Ju Qian Bin Wang Jin-Guo Zhai Feng Ji Xiao-Yan Ke 
To the Editor： In the last 10 years, mounting evidence has confirmed that schizophrenia is associated with white matter （WM） impairment; this impairment exists even before the occurrence of an episode of schizophre...
Transjugular Intrahepatic Portosystemic Shunt as the Treatment for Refractory Hepatic Hydrothorax with Portal Vein Thrombosis
《Chinese Medical Journal》2017年第16期1999-2000,共2页Lin-Hao Zhang Huan Tong Bo Wei Hao Wu Cheng-Wei Tang 
This study was supported by grants from tile National Natural Science Foundation of China （No. 81400637） and the Research Foundation for Residents of West China Hospital.
Hepatic hydrothorax occurs in 4-12% of patients with liver cirrhosis, A part of patients with persisted hydrothorax resists conservative treatment, known as refractory hepatic hydrothorax （RHH）. Portal vein thrombos...
Effects of Appropriate Prolonged Sacral Neuromodulation Testing in Improving Implantation Rate of a Permanent Implantable Pulse Generator in Patients with Refractory Lower Urinary Tract Dysfunctions in China's Mainland被引量：4
《Chinese Medical Journal》2017年第4期439-444,共6页Peng Zhang Jian-Zhong Zhang Li-Yang Wu Xiao-Dong Zhang 
Background： Sacral neuromodulation （SNM） has become an effective method for treating lower urinary tract voiding dysfunction during the past 20 years. Because of the expensive cost, the number of implantable pulse ...
关键词：Lower Urinary Tract Symptoms Sacral Neuromodulation Wound Infection 
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