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Altitudinal variation in thermal vulnerability of Qinghai-Tibetan Plateau lizards under climate warming
《Current Zoology》2025年第1期99-108,共10页Zeyu Zhu Weiguo Du Cong Zhang Wei Yu Xiaolong Zhao Zhensheng Liu Zhigao Zeng 
supported by grants from the National Natural Science Foundation of China(31861143023 and 31872252);the Fundamental Research Funds for the Central Universities(2572019AA09);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA20050201).
The survival of ectotherms worldwide is threatened by climate change.Whether increasing temperatures increase the vulnerability of ectotherms inhabiting temperate plateau areas remains unclear.To understand altitudina...
关键词：climate change Phrynocephalus vlangalii plateau ectotherm thermoregulatory effectiveness thermal sensitivity VULNERABILITY 
The regulatory effect of the asymmetrical dress style on people’s thermal comfort and heat loss
《Building Simulation》2024年第12期2311-2329,共19页Cong Song Dongxue Zhao Yanfeng Liu Jia Li Jinyu Zhao 
supported by the National Natural Science Foundation of China(No.52378107);the State Key Program of National Natural Science Foundation of China(No.U20A20311);the Young Talent Fund of the University Association for Science and Technology in Shaanxi(No.20230429);Shaanxi Province Youth Science and Technology Rising Star Program(No.2024ZC-KJXX-068)。
On the plateau,symmetrical(WDS)and asymmetrical(WLS)dressing habits have been developed to adapt to the extreme climate of the plateau,which is characterized by large temperature variations.Few studies have investigat...
关键词：local heat loss total heat loss Xizang people thermal comfort asymmetrical dressing 
CAMKK2-AMPK axis endows dietary calcium and phosphorus levels with regulatory effects on lipid metabolism in weaned piglets被引量：1
《Journal of Animal Science and Biotechnology》2024年第6期2432-2451,共20页Zhenyan Miao Yanjie Sun Zhangjian Feng Qiwen Wu Xuefen Yang Li Wang Zongyong Jiang Ying Li Hongbo Yi 
financially supported by the National Key Research and Development Program of China(2021YFD1300402);Research Fund of Maoming Branch,Guangdong Laboratory for Lingnan Modern Agriculture(2022ZD003,2021TDQD002);the earmarked fund for China Agriculture Research System(CARS-35);Special Project for Rural Revitalization Strategy in Guangdong Province(2023TS-3-1)。
Background In the realm of swine production,optimizing body composition and reducing excessive fat accumulation is critical for enhancing both economic efficiency and meat quality.Despite the acknowledged impact of di...
关键词：AMPK CAMKK2 Dietary calcium and phosphorus Intestine-liver axis Lipid metabolism 
Regulatory effects of the p38 mitogen-activated protein kinase-myosin light chain kinase pathway on the intestinal epithelial mechanical barrier and the mechanism of modified Pulsatilla decoction(加味白头翁汤)in the treatment of ulcerative colitis
《Journal of Traditional Chinese Medicine》2024年第5期885-895,共11页WU Tingting YANG Xin ZHU Huiping GUO Jinwei ZHU Hui ZHANG Peipei WANG Meng LIANG Guoqiang SUN Hongwen 
Natural Science Foundation of Jiangsu Province-funded Project:Regulation of Intestinal Epithelial Tight Junction Proteins Through the p38 Mitogen-activated Protein Kinase-Myosin Light Chain kinase Signaling Pathway in Ulcerative Colitis Treatment by Modified Pulsatilla Decoction(No.BK20201179);Jiangsu Health Commission-funded Project:Study on the Prevention of Postoperative Recurrence in Patients with Colorectal Adenoma and High Triglyceride based on the Theory of“Treating the Disease Before It Gets Worse”by Modified Jisheng Wumei Pill(BJ23039);Suzhou Health Commission-funded Project:Study on the Technical Application of Xu Jingfan's“Eliminating Stasis and Protecting Membrane”Method to Regulate Recombinant NLR Family,Pyrin Domain Containing Protein 3 to Repair Esophageal Mucosa in Reflux Esophagitis treatment(SS202080),Suzhou Health Commission-funded Project:(SKY2022015),and Suzhou Health Commission-funded Project:Clinical Diagnostic and Therapeutic Techniques for Reflux Esophagitis Treatment with Graded Step-down Therapy by Combining Traditional Chinese and Western medicine(LCZX201817)。
OBJECTIVE:To investigate the mechanism of the protective effect of modified Pulsatilla decoction(加味白头翁汤,MPD)on the mechanical barrier of the ulcerative colitis(UC)intestinal epithelium in vitro and in vivo.METHO...
关键词：COLITIS ULCERATIVE mitogen-activated protein kinase 14 myosin-light-chain kinase modified pulsatilla decoction intestinal epithelial mechanical barrier experimental verification 
Immunoregulatory Effect and Mechanism of Epigallocatechin-3-Gallate in A Mouse Oral Cancer Model
《Proceedings of Anticancer Research》2024年第5期82-88,共7页Yizhen Li Siyi Huang Yanzi Ling Liyan Fu Ruyue Zheng Xinwei Duan Yueji Luo 
Innovation and Entrepreneurship Project for College Students in Changsha Medical University,Changsha Medical Education 2022(Project No.41-149)。
Objective:This investigation delineates the anti-cancer potency of epigallocatechin-3-gallate(EGCG)in an oral cancer mouse model,with a focus on its effect on T-cell activation.Methods:An oral cancer model was establi...
关键词：Epigallocatechin-3-gallate(EGCG) Oral squamous cell carcinoma(OSCC) 4-nitroquinoline 1-oxide(4-NQO) Peripheral blood mononuclear cell(PBMC) Enzyme-linked immunosorbent assay(ELISA) 
Identification of porcine fast/slow myogenic exosomes and their regulatory effects on lipid accumulation in intramuscular adipocytes被引量：1
《Journal of Animal Science and Biotechnology》2024年第4期1512-1527,共16页Tiantian Zhao Tingting Tian He Yu Chaoyue Cao Ziyi Zhang Zhaozhao He Zeqiang Ma Rui Cai Fengna Li Weijun Pang 
supported by the National Natural Science Foundation of China (32272847, U22A20516);the Key Research and Development Program of Shaanxi Province (2022ZDLNY01-04);the China Agriculture Research System of MOF and MARA (CARS-35)。
Background Pork quality is affected by the type of muscle fibers, which is closely related to meat color, tenderness and juiciness. Exosomes are tiny vesicles with a diameter of approximately 30–150 nm that are secre...
关键词：Adipogenesis Exosome Extensor digitorum longus Intramuscular adipocyte Muscle-fat tissue interaction Pig SOLEUS 
The synergistic regulatory effect of PTP1B and PTK inhibitors on the development of Oedaleus decorus asiaticus Bei-Bienko
《Journal of Integrative Agriculture》2024年第8期2752-2763,共12页Shuang Li Sibo Liu Chaomin Xu Shiqian Feng Xiongbing Tu Zehua Zhang 
the National Key R&D Program of China(2022YFD1400500);the earmarked fund for China Agriculture Research System(CARS-34);the Central Public-interest Scientific Institution Basal Research Fund of China(S2022XM21)。
Tyrosine phosphorylation is crucial for controlling normal cell growth,survival,intercellular communication,gene transcription,immune responses,and other processes.protein tyrosine phosphatase(PTP)and protein tyrosine...
关键词：PTP1B PTK INHIBITOR MAPK pathway Oedaleus decorus asiaticus development 
Study on the regulatory effect of liver X receptor in HEK293 cells by six main diterpene esters in Semen Euphorbiae
《TMR Modern Herbal Medicine》2024年第2期35-40,共6页Si-Yuan Ma Fan-Miao Kong Xiao-Tong Wei Jun-Li Zhang Hai-Ting Zhu Xin-Ning Zhang Yu-Feng Hu Ming-Rui Jiang Hui-Nan Wang Yi-Cen Xu Ying-Zi Wang 
supported by National Natural Science Foundation of China(Grant No.82074021).
Background:To study the effects of the main diterpene esters in Euphorbia factor L_(1),L_(2),L_(3),L_(7a),L_(7b)and L_(8)on the transcriptional activity and protein expression of liver X receptor(LXR).Methods:The effe...
关键词：Semen Euphorbiae diterpene esters HEK293 LXR dual luciferase reporter gene system 
Interleukin-33 exerts pleiotropic immunoregulatory effects in response to Plasmodium berghei ANKA(PbA)infection in mice被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2023年第12期521-531,I0004,I0005,共13页Mohammad Faruq Abd Rachman Isnadi Rusliza Basir Ramatu Bello Omenesa Roslaini Abd Majid Maizaton Atmadini Abdullah Che Norma Mat Taib Sivan Padma Priya Yong Yean Kong Chin Voon Kin Gambo Lawal Mukhtar 
supported by the Fundamental Research Grant Scheme(FRGS)from the Malaysia Ministry of Higher Education(FRGS/1/2016/SKK10/UPM/02/1).
Objective:To determine the involvement and the modulatory effects of IL-33 during Plasmodium berghei ANKA(PbA)infection.Methods:PbA infection in male ICR mice was utilized as a model of malaria.Systemically circulatin...
关键词：Plasmodium berghei ANKA Malaria IL-33 IMMUNOLOGY Immunotherapy 
Regulatory effects of miR-19a on MAD2 expression and tumorigenesis in gastric cancer
《Genes & Diseases》2023年第4期1180-1182,共3页J.Bargiela-Iparraguirre J.M.Herrero N.Pajuelo-Lozano M.Perez R.Perona A.G.Quiroga C.Calés I.Sanchez-Perez 
MICINN grant number PID2019-106220RB100.Instituto de Salud CarlosⅢ,Spain,grant PI200335,(all co-financed through Fondo Europeo de Desarrollo Regional(FEDER)"Una manera de hacer Europa");supported by a grant FPU15/04669,funded by Ministerio de Educacion,Cultura y Deporte,Spain.JMH FPI-UAM 2021 from Universidad Auton-oma de Madrid(Molecular BioSciences PhD programme).
Gastric cancer(GC)is worldwide the sixth most diagnosed and third leading cause of cancer deaths,with poor and late prognosis,probably due to post-surgery adjuvant treatment resistance and lack of a thorough panel of ...
关键词：MAD2 TUMORIGENESIS GASTRIC 
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