To the Editor:Venous thromboembolism(VTE)is a common complication following orthotopic liver transplantation(OLT),with an incidence of 2.8-8.6%,[1-3]which affects the quality of life of post-transplant patients.Curren...
supported in part by grants from the National Natural Science Foundation of China (81973993);Zhejiang Provincial Natural Science Foundation of China (LR20C070001).
Dear Editor,Red blood cells(RBCs)are the most abundant cells in the human body.RBCs have been widely investigated as in vivo drug delivery systems due to their unique biological properties.
Background and Purpose: Thrombotic disease is a leading cause of death in industrialized countries. The development of atherosclerosis is a major underlying pathogenesis. Atherosclerotic lesions are largely related to...
In a recent study published in Cell Research,Pan et al.show that thrombomodulin(THBD),a cell surface glycoprotein activator of the thrombin-mediated MAPK pathway,is a key determinant of senescent cell fate.Using the F...
supported by grants from National Institutes of Health(R01CA244564 to X.F.W.,R01DK077794 to A.M.D.);Duke Eye Center EM Facility Core(P30EY005722 to V.Y.A.);NIH Pathway to Independence Award(K99EY033763 to T.R.L.);Florence McAlister Professorship of Medicine(A.M.D.).
Cellular senescence is a stress-induced,stable cell cycle arrest phenotype which generates a pro-inflammatory microenvironment,leading to chronic inflammation and age-associated diseases.Determining the fundamental mo...
supported by the National Clinical Research Center for Geriatric Diseases(No.NCRCGPLAGH-20190003);the Chinese Cardiovascular Health Alliance-Advanced Fund(No.2019-CCAACCESS-054).
BACKGROUND The validation of various risk scores in elderly patients with comorbid atrial fibrillation(AF)and acute coron-ary syndrome(ACS)has not been reported.The present study compared the predictive performance of...
financially supported by the Baotou Science and Technology Bureau Fund Subject(2020Z1009-6).
Objective:To explore the effect of plasma homocysteine(Hcy)levels on methylation and expression of thrombomodulin(TM)gene in patients with retinal vein occlusion(RVO).Methods:11 cases of patients who were diagnosed as...
Key Project of Science and Technology Department of Sichuan Province,No.2022YFS0337.
BACKGROUND Malignant atrophic papulosis is a rare and potentially lethal thrombo-occlusive microvasculopathy characterized by cutaneous papules and gastrointestinal perforation.The precise pathogenesis of this disease...
Dear Editor,I am Dr. Jungyul Park from the Division of Oculoplasty, Department of Ophthalmology, Pusan National University Hospital, Busan, Korea. I am writing to present a case of direct approach to thrombosed superi...
Thrombocytopenia is a multifactorial disorder that is common in patients with chronic liver disease(CLD),leading to challenging perioperative planning.As thrombocytopenia in CLD is associated with thrombopoietin(TPO)d...