financially supported by the Baotou Science and Technology Bureau Fund Subject(2020Z1009-6).
Objective:To explore the effect of plasma homocysteine(Hcy)levels on methylation and expression of thrombomodulin(TM)gene in patients with retinal vein occlusion(RVO).Methods:11 cases of patients who were diagnosed as...
supported by the National Basic Research Program of China (973 Program, 2013CB531705);the National Natural Science Foundation Youth Project of China(81703903 and 81803904)
Objective: To explore the hemostatic mechanism of Jianpi Yiqi Shexue decoction(JYSD) by regulating vascular factors in an immune thrombocytopenia(ITP) mouse model.Methods: An ITP mouse model was established by the pas...
BACKGROUND High mobility group box 1(HMGB1)has been studied as a molecule associated with severe outcomes in sepsis and thrombomodulin(TM)seems to decrease HMGB1 activity.AIM To investigate the role of the thrombomodu...
Objective To investigate the value of P-selectin, thrombomodulin(TM)and von Willebrand factor(vWF)in identifying severe acute pancreatitis(SAP)at an early stage of the disease.Methods 80 patients with acute pancreatit...
supported by the National Basic Research Program of China (2013CB933701, 2013CB933704);the National Natural Science Foundation of China (21127901)
Exposure to cigarette smoke is a major risk factor for cancer and cardiovascular disease. Thrombosis is regarded as the main reason for smoking-related car- diovascular disease. However, the detail mechanism of how sm...
supported by Shanghai Municipal Commission of Health and Family Health Planning Key Projects(NO.20134023)
Objective: To explore application of targeted contrast enhanced ultrasonography in diagnosis of early stage vascular endothelial injury and diabetic nephropathy. Methods: Targeted Sono VueTM microbubble was prepared b...
Fulminant hepatic failure(FHF) is a critical illness that can be comorbid to primary liver damage.FHF shows a high mortality rate,and patients with FHF require intensive therapy,including plasma apheresis.However,inte...
Inflammation and coagulation are so tightly linked that the cytokine storm which accompanies the development of sepsis initiates thrombin activation and the development of an intravascular coagulopathy. This review ex...
AIM: To evaluate the need for thrombomodulin(r TM) therapy for disseminated intravascular coagulation(DIC) in patients with acute cholangitis(AC)-induced DIC. METHODS: Sixty-six patients who were diagnosedwith AC-indu...