the State of New Jersey Commission on Spinal Cord Research grant 15IRG006;Rutgers TechAdvance Fund (to LC)。
Human spinal cord injury (SCI) results in locomotor and sensory disabilities,which severely affect the quality of life.To restore function after SCI,it is necessary to repair and reconstruct the damaged local circuitr...
In rodents,well characterized neurogenic niches of the adult brain,such as the subventricular zone of the lateral ventricles and the subgranular zone of the hippocampus,support the maintenance of neural/stem progenito...
supported by the National Natural Science Foundation of China,No.31500823;the Natural Science Foundation of Jiangsu Province of China,No.BK20150403;the Natural Science Fund for Colleges and Universities in Jiangsu Province of China,No.16KJB180024
The peripheral nervous system has the potential to regenerate after nerve injury owing to the intrinsic regrowth ability of neurons and the permissive microenvironment.The regenerative process involves numerous gene e...
Schwann cells, the myelinating glial cells of the peripheral nervous system are remarkably plastic after nerve trauma. Their transdifferentiation into specialized repair cells after injury shares some features with th...
Glaucoma and other optic neuropathies result in optic nerve degeneration and the loss of retinal ganglion cells(RGCs)through complex signaling pathways.Although the mechanisms that regulate RGC development remain un...
supported by NIH HD057632 to VPL and JLB.VPL holds the Walter G.Ross Distinguished Chair in Developmental Neuroscience
Following injury to the central nervous system(CNS),severed axons fail to regenerate and re-form functional connections.Accordingly,CNS neurons appear to lack the intrinsic ability to modify their gene expression pa...
supported by grants from the Canada Research Chairs program;the NSERC Engage and Engage Plus program
Diseases and disorders of the central nervous system often require significant interventions to restore lost function due to their com- plexity. Examples of such disorders include Parkinson's disease, Alzheimer's di...
Raine Foundation Priming Grant;Australian Research Council Discovery Project Grant(DP772899);Cancer Council WA Suzanne Cavanagh Early Career Research Grant
Few would doubt that understanding the developmental landscape from which a mature neuron is derived is essential to understand its biology.The temporal and spatial position of a cell from the very earliest stages of ...
The development of the spinal cord needs a concerted interaction of transcription factors activating diverse genes and signals from outside acting on the specification of the different cells. Signals have to act on th...
Research in the Mu lab is supported by grants from the National Eye Institute(EY020545);the SUNY/RF Research Collaboration Fund;an unrestricted grant from Research to Prevent Blindness
The retina and its development: The retina is an essential part of the visual system. A myriad of eye diseases are characterized by retinal degeneration, caused by either genetic or environmental factors. This unders...