supported by the Guangdong Basic and Applied Basic Research Foundation(Nos.2020B1515120066 and 2022A1515010010);the National Natural Science Foundation of China[Nos.82293681(82293680)and 82273822];the Science and Technology Key Project of Guangdong Province(No.2020B1111110004);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(No.2017BT01Y036);the Fundamental Research Funds for the Central Universities;the support of K.C.Wong Education Foundation。
The first phloroglucinol-triterpenoid hybrids,myrtphlotritins A-E(1-5),were rapidly recognized and isolated from two species of Myrtaceae by employing the building blocks-based molecular network(BBMN)strategy.Compound...
supported in part by the National Key Research and Development Program of China(No.2022YFC3400501);the National Natural Science Foundation of China(Nos.81825020 and 82150208 to H.L.);the Shanghai Science and Technology Commission Biomedical Science and Technology Support Special Project(Nos.21S11907900 and 20S11901000 to Z.Z.);sponsored by the National Program for Special Supports of Eminent Professionals;the National Program for Support of Top-Notch Young Professionals.
Ursolic acid(UA)is a naturally occurring ursane triterpenoid,which exhibits a wide range of unique biological activities.To clarify its mechanism of action(MOA),a series of fluorescent derivatives of UA(5a-c)were desi...
supported by the National Natural Science Foundation of China(Nos.21572015,21877007,81703540 and 21702007);China Postdoctoral Science Foundation(No.2018M631796);Technology Plan Foundation of Liaoning Province(No.20170520063);Chinese Medicine Related Scientific Research Project of Dalian(No.17Z2013);the open funding of the State Key Laboratory of Phytochemistry and Plant Resources in West China。
The acetyl ester plays an important role for protection of the hydroxyl groups in carbohydrates synthesis.In the present study,we described an efficient deprotection of acetyl group of pentacyclic triterpenoid by usin...
The microbial transformation of glycyrrhetinic acid(1) by Cunninghamella blakesleana CGMCC 3.970 led to the production of five new metabolites(2-6).The structures of the metabolites were determined by extensive sp...
supported by National Science and Technology Supporting Plan of China (No. 2012BAI29B05)
Two new triterpenoid saponins, named ginsenoside Rh10(1) and notoginsenoside ST-6(2), were isolated from notoginseng medicinal fungal substance. Their structures were elucidated by a combination of 1D and 2D NMR, ...
supported by the Key International Cooperation Project of CMST (No. 2008DFA31040);the Special Funds for Young Teachers of Ocean University of China (No.841113070)
A continuing phytochemical study on the semi-mangrove plant Hibiscus tiliaceus yielded two new tetracyclic triterpenoids (3β,24S)-19(10→9)-abeo-8α,9β,10α-eupha-5,25(26)-dien-3,24-diol (tiliacol A, 1 ), a...
An unusual oleanane triterpene(1) was isolated from aerial parts of Rhododendron campanulatum.The compound had shown prominent antibacterial and immunomodulatory activities.The structure of the compound was determin...
supported by E&T Modern Center for Natural Products of Liaoning Province of China (No.2008402021)
Two new cucurbitane-type triterpenoids,(23E)-5β,19-epoxycucurbita-6,23,25-triene-3β-ol(1) and(19R,23E)-5/β,19-epoxy- 19-ethoxycucurbita-6,23-diene^3β,25-diol(2),together with three known compounds,have bee...
grant(No.F/2624-3F) from the International Foundation for Science(Sweden)
A new friedelane-type triterpene named 3β-hydroxyfriedelane-7,12,22-trione,as well as nine known compounds were isolated from the whole stems of Drypetes laciniata Hutch.(Euphorbiaceae).Their structures were establ...
A new triterpenoid,possessing a lanost-9(11)-3-one skeleton,was isolated from the roots of Kadsura coccinea,based on the spectral analysis,its structure was elucidated as 3-hydroxy-12-acetoxycoccinic acid.