Objectives To evaluate the urinary kidney injury molecule-1(KIM-1)as a predictor for early detection of acute kidney injury in cases with obstructive nephropathy in an animal model and to correlate urinary KIM-1 with ...
Ratchadapisek Research Funds,Faculty of Medicine,Chulalongkorn University;King Chulalongkorn Memorial Hospital,Thai Red Cross Society。
Aims:Nonalcoholic fatty liver disease(NAFLD)and chronic kidney disease(CKD)are common diseases worldwide.Reports of a high prevalence of CKD in NAFLD patients have been documented.Urinary neutrophil gelatinaseassociat...
This study was supported by grants from the Guangdong Provincial Science and Technology Project (No. 2014A020212662), the Science and Technology Planning Project of Southern Medical University (No. CX2016N018), the Science and Technology Planning Project of Tianhe District, Guangzhou City (No. 201704KW011), The Natural Science Foundation of Guangdong Province (2016A030313559), and The South Wisdom Valley Innovative Research Team Program (No. CXTD-004, 2014).
Objective: Diabetic kidney disease (DKD) has become one of the major causes of end-stage renal disease. Urinary extracellular vesicles (uEVs) contain rich biological information which could be the ideal source fo...
Objective:The aim of this study was to discover the potential biomarkers changes on a rat model of isoproterenol (ISO) induced myocardial ischaemia before and after treatment with a Xiangdan submicron emulsion and to ...
The Project of the National Natural Sciences Foundation of China(81373239,30973369).
Drug abuse has become a global problem.The mass spectrometry‑based metabolic consequences of ketamine administration in anesthesia and therapy have been well studied,but to the best of our knowledge,metabolomic studie...
Objective To identify novel biomarker for diabetic nephropathy(DN)by urinary proteomic methods,and to detect the expression of E-cadherin in urine and renal tissue of patients with DN.Methods Urine samples were collec...
Background: Estrogen exposure plays a role in breast cancer (BC) development. A novel estrogen biomarker, the estrogen DNA adduct (EDA) ratio, was shown to be elevated in women at high-risk of BC and among BC cases. M...
The aim of this study was to assess the relationship between pre-prostatectomy urinary Engrailed-2 (EN2), a transcription factor secreted by prostate cancer cells, with tumour volume and pathological characteristics i...
Supported by The Key Program of Science and Technology Commission of Shanghai Municipality,Project No.09JC1411600;Natural Science Foundation of Shanghai,No.08ZR1411300
AIM:To gain new insights into tumor metabolism and to identify possible biomarkers with potential diagnostic values to predict tumor metastasis.METHODS:Human gastric cancer SGC-7901 cells were implanted into 24 severe...