云南高校图书馆联盟文献共享服务平台- ABATACEPT

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Efficacy of abatacept treatment in a patient with enteropathy carrying a variant of unsignificance in CTLA4 gene:A case report: 《World Journal of Clinical Cases》2023年第26期6176-6182,共7页Ugur Musabak Tuba Erdoğan Serdar Ceylaner EmreÖzbek Nuretdin Suna Binnaz HandanÖzdemir; BACKGROUND Cytotoxic T Lymphocyte Antigen-4(CTLA4)deficiency is a genetic defect that causes a common variable immunodeficiency(CVID)clinical phenotype.Several studies have reported an association between CTLA mutatio...; 关键词：Common variable immunodeficiency ABATACEPT CTLA4 antigen Case report

Difficult-to-treat rheumatoid arthritis treated with Abatacept combined with Baricitinib:A case report: 《World Journal of Clinical Cases》2023年第11期2474-2481,共8页Jia-Ping Qi Huan Jiang Teng Wu Yuan Zhang Wei Huang Yi-Xuan Li Jing Wang Ju Zhang Zhen-Hua Ying; BACKGROUND Sporadic cases of rheumatoid arthritis(RA)due to unsatisfactory responses to Abatacept(ABT)have been reported;however,the rescue therapy has not been finalized.Here,we present a case with difficult-to-treat...; 关键词：Difficult-to-treat rheumatoid arthritis ABATACEPT Baricitinib Combination therapy Case report

美国FDA批准阿巴西普(abatacept)用于预防急性移植物抗宿主病: 《广东药科大学学报》2022年第2期99-99,共1页夏训明(编译); 美国FDA于2021年12月15日批准Orencia(abatacept/阿巴西普,商品名中译“恩瑞舒”)与其他免疫抑制剂联合用药用于成人及2岁以上儿童预防急性移植物抗宿主病,主要适用于非血缘造血干细胞移植(即常说的骨髓移植或者干细胞移植)患者。Orenci...; 关键词：急性移植物抗宿主病银屑病关节炎其他免疫抑制剂风湿性关节炎共刺激信号骨髓移植干细胞移植阻滞剂

Abatacept is effective in Chinese patients with LRBA and CTLA4 deficiency: 《Genes & Diseases》2021年第5期662-668,共7页Lu Yang Xiuhong Xue Xuemei Chen Junfeng Wu Xi Yang Li Xu Xuemei Tang Mo Wang Huawei Mao Xiaodong Zhao; This work was supported by the Research Fund for Outstanding Youth Scholar of Chongqing Talents[grant number CQYC201905003];Science and Technology Research Program of Chongqing Municipal Education Commission[grant number KJZD-M201800401];High-level Medical Reserved Personnel Training Project of Chongqing[grant number 2019181].; CTLA4 deficiency and LRBA deficiency are a group disorders of immune dysregula-tion that affect CTLA4 pathway.The patients mainly present with autoimmunity,antibody defi-ciency and recurrent infections.Here we reporte...; 关键词：LRBA deficiency CTLA4 deficiency Target therapy ABATACEPT EFFICACY

Anaphylactic Reaction to a Change in the Route of Administration of Abatacept: A Case Study被引量：1: 《Open Journal of Rheumatology and Autoimmune Diseases》2020年第2期64-69,共6页Kan Imai Daisaku Tokunaga Masashi Ishida; The incidence of anaphylactic reaction after the long-term use of abatacept has not been reported until now. Herein, we present a case of rheumatoid arthritis (RA) in which the patient experienced an anaphylactic reac...; 关键词：RHEUMATOID ARTHRITIS ABATACEPT Anaphylactic REACTION

Risk of hepatitis B virus reactivation in rheumatoid arthritis patients undergoing biologic treatment: Extending perspective from old to newer drugs被引量：3: 《World Journal of Hepatology》2015年第3期344-361,共18页Francesca De Nard Monica Todoerti Vittorio Grosso Sara Monti Silvia Breda Silvia Rossi Carlomaurizio Montecucco Roberto Caporali; Hepatitis B virus(HBV) reactivation in rheumatoid arthritis(RA) patients undergoing biological therapy is not infrequent. This condition can occur in patients with chronic hepatitis B as well as in patients with resol...; 关键词：Rheumatoid arthritis Hepatitis B virus BIOLOGICS ANTI-TNF RITUXIMAB TOCILIZUMAB ABATACEPT

Costimulatory blockade:A novel approach to the treatment of glomerular disease?被引量：1: 《World Journal of Methodology》2015年第2期20-25,共6页Pasquale Esposito Teresa Rampino Antonio Dal Canton; Costimulatory pathways(Cluster of differentiation 28,tumor necrosis factor-related,adhesion and T Cell Ig-and mucin-domain molecules) regulating the interactions between receptors on the T cells andtheir ligands expre...; 关键词：COSTIMULATION GLOMERULONEPHRITIS Cluster of differentiation 80 Cytotoxic T-lymphocyte-associated antigen-4 Lupus nephritis ABATACEPT PROTEINURIA PODOCYTES

Distinct Cytokine Profiles in Patients with Oligoarticular Juvenile Idiopathic Arthritis after <i>in</i><i>Vitro</i>Blockade of T Cells by Cyclosporine and Abatacept: 《World Journal of Vaccines》2014年第3期133-146,共14页Leo Strothmann Martina Kirchner Anja Sonnenschein Wilma Mannhardt-Laakmann; Oligoarticular juvenile idiopathic arthritis (oJIA) is an antigen-driven and lymphocyte-mediated disorder affecting the adaptive immune system. Auto reactive T cells produce pro-inflammatory cytokines as IFN-γ and IL...; 关键词：Juvenile IDIOPATHIC Arthritis Pathogenesis Cytokines T Cell Inhibition

欧盟批准百时美施贵宝abatacept新适应证: 《世界临床药物》2010年第8期I0002-I0002,共1页; 百时美施贵宝2010年7月宣布，欧盟已批准其abatacept（Orencia）的新适应证，即与甲氨蝶呤联用于治疗对先前使用的一种及以上缓解病情用抗风湿药（DMARD）应答不充分的成年患者中至重度活动性类风湿关节炎。; 关键词：ABATACEPT 新适应证欧盟活动性类风湿关节炎成年患者抗风湿药甲氨蝶呤

NICE建议采用abatacept治疗类风湿性关节炎: 《国外药讯》2010年第7期5-5,共1页; 国家卫生与临床评价研究所（NICE）公布最终评估裁定（FAD），建议对抗TNF（TNF-α抑制剂）反应不佳和使用Ritux—imab有禁忌或因不良事件停用的患者，使用Orencia（abatacept）（Ⅰ）治疗。; 关键词：PT治疗类风湿性关节炎 NICE TNF-Α抑制剂临床评价不良事件研究所

ABATACEPT