ACACETIN

作品数：9被引量：68H指数：3
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相关领域：医药卫生更多>>
相关作者：丁怡李建北董倩赵宁杜丽丽更多>>
相关机构：厦门大学中国医学科学院北京协和医学院华中科技大学华中科技大学同济医学院附属协和医院更多>>
相关期刊：《Neural Regeneration Research》《Journal of Traditional Chinese Medical Sciences》《Journal of Hainan Medical University》《Advances in Bioscience and Biotechnology》更多>>
相关基金：国家自然科学基金更多>>
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Targeting colorectal cancer with Herba Patriniae and Coix seed:Network pharmacology,molecular docking,and in vitro validation被引量：2
《World Journal of Gastrointestinal Oncology》2024年第8期3539-3558,共20页Cheng-Lei Wang Bing-Wei Yang Xin-Yan Wang Xue Chen Wei-Dong Li Hao-Yu Zhai Ying Wu Mu-YaoCui Jia-He Wu Qing-Hui Meng Nan Zhang 
Supported by the National Natural Science Foundation of China,No.82174464;China Academy of Traditional Chinese Medicine Science and Technology Innovation Project,No.CI2021A01806;Central High Level Traditional Chinese Medicine Hospital Clinical Research and Achievement Transformation Ability Enhancement Project,No.HLCMHPP2023085.
BACKGROUND Herba Patriniae and Coix seed(HC)constitute a widely utilized drug combination in the clinical management of colorectal cancer(CRC)that is known for its diuretic,anti-inflammatory,and swelling-reducing prop...
关键词：Colorectal cancer Baijiangcao(Herba Patriniae) Yiyiren(Coix seed) ACACETIN PROLIFERATION MIGRATION Apoptosis Network pharmacology 
Effect of acacetin on inhibition of apoptosis in Helicobacter pyloriinfected gastric epithelial cell line
《World Journal of Gastrointestinal Oncology》2024年第8期3624-3634,共11页Qi-Xi Yao Zi-Yu Li Hou-Le Kang Xin He Min Kang 
Supported by the Doctoral Research Initiation Fund of Affiliated Hospital of Southwest Medical University,No.21037.
BACKGROUND Helicobacter pylori(H.pylori)infection can cause extensive apoptosis of gastric epithelial cells,serving as a critical catalyst in the progression from chronic gastritis,gastrointestinal metaplasia,and atyp...
关键词：Gastric epithelial GES-1 cells Helicobacter pylori Infection ACACETIN Antibiotic resistance APOPTOSIS 
Genome assembly of the snow lotus species Saussurea involucrata provides insights into acacetin and rutin biosynthesis and tolerance to an alpine environment
《Horticulture Research》2023年第10期8-11,共4页Yanxia Sun Aidi Zhang Jacob BLandis Wei Shi Xiujun Zhang Hang Sun Hengchang Wang 
This work was supported by grants from the National Natural Science Foundation of China(U2003122);the Second Tibetan Plateau Scientific Expedition and Research(STEP)program(2019QZKK0502).Sequencing service was provided by Bioyi Biotechnology Co.,Ltd.Wuhan,China。
Dear Editor,Understanding the evolution and survival mechanisms of endangered wild medicinal herbs is crucial for their cultivation,utilization,and conservation.The snow lotus species Saussurea involucrata(Kar.&Kir.)S...
关键词：TIANSHAN belongs INVOLUCRATA 
Effect of Acacetin on flagellin induced NLRC4 inflammasome activation in mouse bone marrow-derived macrophages
《Journal of Hainan Medical University》2022年第17期14-17,共4页Wang Zhao-xia Bu Juan Zhang Xiao-ling MAHAN Yeledan Wu Xuan-xia Zhou ling 
Xinjiang Uygur Autonomous Region Natural Science Foundation(No.2020D01C095);Xinjiang Uygur Autonomous Region Outstanding Young Scientist and Technological Talents Training Project(No.2020Q046);Xinjiang Uygur Autonomous Region People's Hospital In-Hospital Project(No.20210102)。
Objective:To investigate the effect of acacetin on flagellin induced NLRC4 inflammasome activation in mouse bone marrow-derived macrophages(BMDMs).Methods:Mouse BMDMs were divided into control group,LPS group,LPS+flag...
关键词：FLAGELLIN ACACETIN NLRC4 ACTIVATION MACROPHAGES 
Identification and interspecies characterization of UDP-glucuronosyltransferase isoforms catalyzing acacetin glucuronidation using recombinant UGT enzymes and microsomes被引量：3
《Journal of Traditional Chinese Medical Sciences》2019年第2期155-163,共9页Kangle Shi Shan Li Qinggang Meng 
the National Natural Science Foundation of China(81473800).
Objective:To explore the glucuronic acid metabolism of acacetin in human liver and intestinal microsomes to better characterize human uridine 5'-diphospho (UDP)-glucuronosyltransferase (UGT) isoforms.In addition,inter...
关键词：ACACETIN UDP-GLUCURONOSYLTRANSFERASES Human liver MICROSOMES GLUCURONIDATION Species differences 
Acacetin protects against cerebral ischemia-reperfusion injury via the NLRP3 signaling pathway被引量：28
《Neural Regeneration Research》2019年第4期605-612,共8页Juan Bu Shen Shi Hui-Qin Wang Xiao-Shan Niu Zong-Feng Zhao Wei-Dong Wu Xiao-Ling Zhang Zhi Ma Yan-Jun Zhang Hui Zhang Yi Zhu 
supported by the Natural Science Foundation of Xinjiang Uygur Autonomous Region of China,No.2016D01C120(to JB)
Acacetin(5,7-dihydroxy-4′-methoxyflavone), a potential neuroprotective agent, has an inhibitory effect on lipopolysaccharide-induced neuroinflammatory reactions. However, whether acacetin has an effect on inflammator...
关键词：nerve REGENERATION ACACETIN cerebral ISCHEMIA-REPERFUSION injury microglia NLRP3 inflammasome inflammatory FACTOR INFARCT volume signaling pathway nuclear factor-κB neuroprotection neural REGENERATION 
Combination of Acacetin with Antibiotics against Methicillin Resistant <i>Staphylococcus aureus</i>Isolated from Clinical Specimens被引量：1
《Advances in Bioscience and Biotechnology》2014年第4期398-408,共11页Jeong-Dan Cha Sung-Mi Choi Jeong Hye Park 
Methicillin-restitant Staphylococcus aureus (MRSA) is very dangerous bacteria and one of the most feared nosocomial germs. In this study, acacetin was evaluated against 20 clinical isolates of MRSA, either alone or in...
关键词：ACACETIN METHICILLIN-RESISTANT Staphylococcus aureus Minimum INHIBITORY CONCENTRATIONS Minimum Bactericidal CONCENTRATIONS Time-Kill Curves Fractional INHIBITORY Concentration 
Two New Flavonoid Glycosides from Chrysanthemum morifolium被引量：10
《Chinese Chemical Letters》2006年第8期1051-1053,共3页Jian ZHANG An Wei DING You Bin LI Da Wei QIAN Jin Ao DUAN Zhi Qi YIN 
supported by the Natural Science Foundation of Jiangsu Science and Technology Department(No.BK2001219)
Two new flavonoid glycosides were isolated from the flowering heads of Chrysanthemum morifolium. Their structures were determined to be luteolin 4＇-methoxy-7- O-（6＂-O-acetyl）-β-D-glucopyranoside （1） and acaceti...
关键词：Chrysanthemum morifolium flavonoid glycosides luteolin 4＇-methoxy-7-O-（6＂-O-acetyl）-β-D-glucopyranoside acacetin 7-O-（3＂-O-acetyl）-β-D-glucopyranoside. 
香青兰化学成分的研究被引量：24
《中国中药杂志》2001年第10期697-698,共2页李建北 丁怡 
目的 :研究香青兰全草的化学成分。方法 :RA型大孔树脂和硅胶柱色谱法分离纯化 ,薄层色谱及光谱法进行结构鉴定。结果 :从乙醇提取物中分得 4个化合物 ,鉴定为tilianin ,agastachoside,acacetin和oleanolicacid。结论
关键词：香青兰 tillianin agastachoside ACACETIN 化学成分 研究 
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