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ADJUVANT: 作品数：496被引量：1918H指数：20; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：郭虹陈观今郑焕钦许小琴饶平凡更多>>; 相关机构：中山大学吉林大学第二军医大学福州大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金高等学校学科创新引智计划更多>>

Astragalus polysaccharide orβ-glucan combined with inactivated vaccine markedly prevent CyHV-2 infection in Carassius auratus gibelio: 《Aquaculture and Fisheries》2024年第5期763-775,共13页Xingchen Huo Yiyi Yan Jiao Chang Jianguo Su; supported by Fundamental Research Funds for the Central Universities (2662021SCPY006);National Key Research and Development Program of China (2018YFD0900504).; Herpesviral hematopoietic necrosis disease caused by cyprinid herpesvirus 2(CyHV-2)results in huge economic losses for the gibel carp(Carassius auratus gibelio)aquaculture industry.A vaccination strategy is a feasible...; 关键词：Carassius auratus gibelio Cyprinid herpesvirus 2(CyHV-2) Β-GLUCAN ADJUVANT Astragalus polysaccharide(APS) VACCINE

A tumor-targeting nano-adjuvant for in situ vaccine based on ultrasound therapy: 《Aggregate》2024年第3期290-298,共9页Linjie Cui Haochen Yao Fuxin Xue Jiali Sun Xitong Ren Mengfei Zheng Zhilin Liu Zhaohui Tang; Ministry of Science and Technology of China,Grant/Award Number:2022YFE0110200;Natural Science Foundation of Jilin Province,Grant/Award Number:20230101037JC;National Natural Science Foundation of China,Grant/Award Numbers:52203198,52025035。; Ultrasound-generated antigens combined with TLR7/8 agonists as adjuvants have demonstrated significant anti-tumor efficacy as an in-situ vaccine.However,the use of TLR7/8 agonists can cause severe inflammatory respons...; 关键词：IMMUNOTHERAPY in situ vaccine R848 nanoparticles TUMOR-TARGETING ultrasound therapy

Recent advances on vaccines against malaria: A review: 《Asian Pacific Journal of Tropical Medicine》2024年第4期143-159,共17页Shiza Malik Yasir Waheed; This review aims to summarize the currently viable vaccine strategies including the approved vaccines and the those in trials for next-generation malaria vaccines.Data on malaria vaccine development was collected thro...; 关键词：Vaccines against malaria Drugs and adjuvant Malarial treatment PLASMODIUM RTS S vaccine

Enhancement of SARS-CoV-2 vaccine-induced immunity by a Toll-like receptor 7 agonist adjuvant: 《Signal Transduction and Targeted Therapy》2023年第6期2481-2484,共4页Gen Li Meixing Yu Qiong Ke Jing Sun Yanwen Peng Chuanfeng Xiong Olivia Monteiro COVID-Infection and Immunity Investigation Group Jincun Zhao Andy P.Xiang; research funding from Guangzhou Women and Children Medical Center,the National Key Research and Development Program of China(2018YFA0107200);National Natural Science Foundation of China(81730005 and 31771616);Macao FDCT(FDCT 0106/2021/A)。; Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is an enveloped positive-sense single-stranded RNA(ssRNA)virus responsible for the global COVID-19 pandemic.Although vaccines for SARS-CoV-2 have ...; 关键词：IMMUNITY VACCINE PATTERN

Immunologically effective biomaterials-enhanced vaccines against infection of pathogenic microorganisms被引量：1: 《Biosafety and Health》2023年第1期45-61,共17页Qi Wei Shixian Liu Xu Huang Hua Xin Jianxun Ding; the National Key Research and Development Program of China(Nos.2022YFC2603500/2022YFC2603501 and 2021YFC2400600/2021YFC2400603/2021YFC2400604);the National Natural Science Foundation of China(Nos.52273158,U21A2099,52022095,51973216,and 51873207);the Science and Technology Development Program of Jilin Province(Nos.20220204018YY,20210509005RQ,20210504001GH,and 20200404182YY);the Youth Innovation Promotion Association of Chinese Academy of Sciences(No.2019230);the Special Project for City–Academy Scientific and Technological Innovation Cooperation of Changchun(No.21SH14);the Fundamental Research Funds for the Central Universities,JLU.; Infectious diseases are severe public health events that threaten global health.Prophylactic vaccines have been considered as the most effective strategy to train the immune system to recognize and clear pathogenic in...; 关键词：Immunologically effective biomaterial POLYMER ADJUVANT VACCINE Pathogenic microorganism infection Prevention and treatment

The protective effects of a D-tetra-peptide hydrogel adjuvant vaccine against H7N9 influenza virus in mice: 《Chinese Chemical Letters》2023年第1期211-214,共4页Keda Chen Xiaoxin Wu Qingjing Wang Ying Wang Haiyan Zhang Shuai Zhao Chaonan Li Zhiwen Hu Zhimou Yang Lanjuan Li; the support from the Medical and Health Science and Technology Program of Zhejiang Province,China(No.2020379356);the China Postdoctoral Science Foundation(No.2020T130102ZX)。; Repeated waves of influenza virus H7N9 epidemics after 2013 have caused severe influenza in humans,with mortality reaching approximately 40%–50%.To prevent possible pandemics,the development of highly effective vacci...; 关键词：H7N9 influenza virus HYDROGEL ADJUVANT VACCINE Preventative effects

Innovative adjuvant augments potency of a SARS-CoV-2 subunit vaccine被引量：1: 《Cell Research》2022年第4期331-332,共2页Hua Peng Yang-Xin Fu; New adjuvants that potently improve vaccine efficacy with extremely low toxicity are urgently needed.In a recent study in Cell Research,Liu et al.show that a new STING agonist CF501 facilitates a SARS-CoV-2 subunit va...; 关键词：VACCINE ADJUVANT al.

Genetically-engineered“all-in-one”vaccine platform for cancer immunotherapy被引量：2: 《Acta Pharmaceutica Sinica B》2021年第11期3622-3635,共14页Aihua Wu Yingzhi Chen Hairui Wang Ya Chang Meng Zhang Pengfei Zhao Yisi Tang Qin Xu Zhuangzhi Zhu Yang Cao Yongzhuo Huang; support of National Key Research and Development Program of China(2021YFE0103100,China);National Natural Science Foundation of China of China(81925035,81673382,and 81521005,China);National Special Project for Significant New Drugs Development(2018ZX09711002-010-002,China);Shanghai SciTech Innovation Initiative(19431903100,18430740800,China);Shanghai Collaborative Innovation Group of Early Diagnosis and Precise Treatment of Hemangiomas and Vascular Malformations(SSMU-ZDCX20180701,China);Chinese Pharmaceutical Association-Yiling Pharm Joint Grants(CPAYLJ201901,China)for the support。; An essential step for cancer vaccination is to break the immunosuppression and elicit a tumor-specific immunity.A major hurdle against cancer therapeutic vaccination is the insufficient immune stimulation of the cance...; 关键词：TRICHOSANTHIN LEGUMAIN TRP2 Transcutaneous immunization ADJUVANT Cancer vaccine Protein engineering

Cationic nanocarriers as potent adjuvants for recombinant S-RBD vaccine of SARS-CoV-2: 《Signal Transduction and Targeted Therapy》2021年第1期8-10,共3页Hong Lei Aqu Alu Jingyun Yang Cai He Weiqi Hong Zesheng Cheng Li Yang Jiong Li Zhenling Wang Wei Wang Guangwen Lu Xiawei Wei; This work was supported by the National Key Research and Development Program of China(No.2016YFA0201402);National Natural Science Foundation Regional Innovation and Development(U19A2003);The National Major Scientific and Technological Special Project for“Significant New Drugs Development”(No.2018ZX09733001).; Dear Editor,The worldwide outbreak of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection has urged the investigation of preventive vaccines.Recently,our team has developed a recombinant protein vacci...; 关键词：ADJUVANT VACCINE stimulation

Development of novel cationic microemulsion as parenteral adjuvant for influenza vaccine: 《Asian Journal of Pharmaceutical Sciences》2020年第5期591-604,共14页Sakalanunt Lamaisakul Angkana Tantituvanont Vimolmas Lipipun Garnpimol Ritthidej; Research grant from the Office of Higher Education Commission via Chulalongkorn University,the fiscal year 2014–2015 is acknowledged。; Squalene-based oil-in-water(O/W)emulsions have been used as effective and safe adjuvants in approved influenza vaccines.However,there are concerns regarding the safety and side effects of increasing risk of narcolepsy...; 关键词：Cationic microemulsion ADJUVANT Influenza virus VACCINE

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