supported by the National Key Research and Development Program of China(2022YFC2303100);the National Natural Science Foundation of China(Nos.52203162,22075078);Program of Shanghai Academic/Technology Research Leader(20xD1421400);China National Postdoctoral Program for Innovative Talents(Bx20220108);the China Postdoctoral Science Foundation(2021M701198);Open Research Fund of State Key Laboratory of Polymer Physics and Chemistry(Changchun Institute of Applied Chemistry,Chinese Academy of Sciences),the Open Project of Engineering Research Center of Dairy Quality and Safety Control Technology(Ministry of Education,R202201);Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Shanghai Municipal Education Commission);Research Center of Analysis and Test of East China University of Science and Technology for the help on the characterization in this manuscript.
The intensive use of antibiotics intensifies the development of bacterial resistance,which has become a serious problem globally.Methicillin-resistant Staphylococcus aureus(MRSA)has resulted in significant morbidity a...
Russian Science Foundation(19-13-00411-P);O.A.K.acknowledges the support from the Stipend of the President of Russian Federation(SP-2022).
Comprehensive Summary Herein,we present a facile synthesis of amide-type water-soluble fullerene derivatives decorated with five residues of amino acids.As compared to the previously developed approaches,the proposed ...
Research reported in this publication was supported by the National Natural Science Foundation of China(Nos.91856113,51873211).
A series of novel bifunctional single-molecule hydrogen-bonding organocatalysts based on fluorinated tertiary alcohol were synthe-sized to mediate the metal-free polymerization of α-amino acid N-carboxyanhydride(NCA)...
Two series of N-pyridylpyrazolecarboxamide derivatives were designed and synthesized by introducing D-alanine acid esters and D-serine acid esters into the skelecton of chlorantraniliprole. The obtained structures wer...
7-epi-Taxane has been achieved efficiently in gram scale from natural taxane via inversion of the 7-hydroxyl group simply using Ag20 as catalyst and DMF as solvent. The catalyst could he quantitatively recovered by fi...
We are grateful for financial support from the National Natural Science Foundation of China(No.21232007).
A chiral phase-transfer catalyst,derived from the combination of cinchona alkaloid backbone and BINOL skeleton,enabled a Mannich reaction of glycine Schiff base with N-Boc-imines to generateα,β-diamino acid derivati...
The self-assembly of the precatalyst modules, which are amino acids and cinchona alkaloid derivatives, leads to the direct formation of the desired organocatalysts without any synthesis. These modularly designed organ...
A new kind of chiral diphosphine PyrPhos-functionalized codendrimers have been synthesized via a liq- uid-phase strategy in high yields. The resulting dendrimeric PyrPhos ligands were purified by a simple solvent pre-...
Project supported by the National Natural Science Foundation of China (Nos. 20472071, 20562014 and 30860342) and Natural Science Foundation of Yunnan Province (No. 2009cc017).
All four isomers of a novel fl-branched unusual amino acid were designed and synthesized with high stereoselectivity (〉 90% de) and in 33%--44% overall yields by the use of 4(R/S)-5,5-dimethyl-4-phenyl-oxazolidin...
Project supported by the National Natural Science Foundation of China (No. 21032006).
An enantioselective Michael addition of ethyl 4,4,4-trifluoro-3-oxobutanoate to α,β-unsaturated ketone esters using a chiral alkyl-substituted thiourea catalyst is reported. Excellent levels of stereo-induction (up...