supported by grants from Major Project of Science and Technology of Guangxi Zhuang Autonomous Region,No.Guike-AA22096018(to JY);Guangxi Key Research and Development Program,No.AB22080053(to DD);Major Project of Science and Technology of Guangxi Zhuang Autonomous Region,No.Guike-AA23023004(to MZ);the National Natural Science Foundation of China,Nos.82260021(to MZ),82060315(to DD);the Natural Science Foundation of Guangxi Zhuang Autonomous Region,No.2021GXNSFBA220007(to GD);Clinical Research Center For Medical Imaging in Hunan Province,No.2020SK4001(to JL);Key Emergency Project of Pneumonia Epidemic of Novel Coronavirus Infection in Hunan Province,No.2020SK3006(to JL);Science and Technology Innovation Program of Hunan Province,No.2021RC4016(to JL);Key Project of the Natural Science Foundation of Hunan Province,No.2024JJ3041(to JL).
Sleep disturbances are among the most prevalent neuropsychiatric symptoms in individuals who have recovered from severe acute respiratory syndrome coronavirus 2 infections.Previous studies have demonstrated abnormal b...
supported by NIH/NIMH grant R01MH111619(to SQ),R21AG078700(to SQ);Institute of Mental Health Research(IMHR,Level 1 funding,to SQ and DF);institution startup fund from The University of Arizona(to SQ)。
Loss of synapse and functional connectivity in brain circuits is associated with aging and neurodegeneration,however,few molecular mechanisms are known to intrinsically promote synaptogenesis or enhance synapse functi...
supported by National Institute of Neurological Disorders and Stroke of the National Institutes of Health under award number R21NS114763;US Army Medical Research and Materiel Command (USAMRMC) under award#W81XWH-18-1-0773;merit-based career enhancement award at the Feinstein Institutes for Medical Research (to CL)
Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfus...
funded by the National Research Developm ent and Innovation Office (NKFIH-K1468 73) (to BP)。
Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events a...
supported in part by the research grant from the National Institute of Neurological Disorders and Stroke,No.R01NS 12137 (to HYC);funded in whole or in part by Aligning Science Across Parkinson's (No.ASA P-0205 720) through the Michael J.Fox Foundation for Parkinson's Research (MJFF)。
Parkinson's disease is a chronic and progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta,which leads to the featured motor impairment of parki...
supported by the National Key R&D Program of China,No.2020YFC2008302;the National Natural Science Foundation of China,No.81673631;the Science and Technology Program of Sichuan Province,No.2020YFH0059 (all to YL)。
Gabapentinoid drugs(pregabalin and gabapentin) have been successfully used in the treatment of neuro pathic pain and in focal seizure prevention.Recent research has demonstrated their potent activities in modulating n...
supported by the Spanish Ministerio de Ciencia, Innovación y Universidades, No. RTI2018-099908-B-C21 (to CC);the Consejería de Economía, Conocimiento, Empresas y Universidades, No. FEDER-UCA18-106647 (to CC);the Consejería de Salud y Familias 80% co-financed by EDRF ITI regional funds, No. ITICadiz-0042-2019 (to CC).
The existence of neural stem cells(NSC)in specific areas of the adult mammalian brain leads to the generation of new neurons involved in homeostatic mechanisms.This is the case of the NSC of the subventricular zone(SV...
In pat i e nt s,a s well as in animal mod e l s,hypersensitivity to external stimuli(hyperalgesia and allodynia)or spontaneous pain is often the first,and the most disabling,symptom of neuropathy(Davis et al.,2020).Th...
supported by the SystemsX-NeuroStemX and Swiss National Science Foundation,No.51RT-0_145728(to VT and TM)。
The cerebral cortex is composed of billions of neurons and glia that are generated sequentially during corticogenesis.These cells are generated in an organized fashion during development.At early stages of brain devel...
supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation),No.424778381-TRR 295(to MM)。
Parkinson’s disease(PD)is a complex neurodegenerative disorder characterized by a range of motor symptoms such as bradykinesia,resting tremor,rigidity,and postural instability,as well as non-motor symptoms,such as de...