ESSENTIAL

作品数:804被引量:2001H指数:21
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相关领域:医药卫生更多>>
相关作者:陈汐敏丁贵鹏接雅俐唐震邹建刚更多>>
相关机构:中国科学院复旦大学北京大学南京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家社会科学基金更多>>
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PIWI-specific insertion module: a newly identified regulatory element essential for longer pi RNAs loading and male fertility被引量:1
《Science China(Life Sciences)》2023年第7期1708-1710,共3页Chunyu Liu Feng Zhang 
Small noncoding RNAs (sn RNAs) such as short interfering RNAs (si RNAs), micro RNAs (mi RNAs), and PIWI-interacting RNAs (pi RNAs) play important roles in diverse cellular processes. These small regulatory RNA molecul...
关键词:INSERTION FERTILITY element 
Disease resistance conferred by components of essential chrysanthemum oil and the epigenetic regulation of OsTPS1被引量:2
《Science China(Life Sciences)》2023年第5期1108-1118,共11页Chuansong Zhan Long Lei Hao Guo Shen Zhou Congping Xu Zixin Liu Zichen Wu Yuan Deng Yuanyuan Miao Yu Han Meng Zhang Hua Li Sishu Huang Chenkun Yang Feng Zhang Yufei Li Ling Liu Xianqing Liu Hafiz Muhammad Khalid Abbas Alisdair R.Fernie Meng Yuan Jie Luo 
supported by the Hainan Major Science and Technology Project(ZDKJ202002);the National Natural Science Foundation of China(32100318);China Postdoctoral Science Foundation(2021TQ0093);Hainan Yazhou Bay Seed Laboratory(B21Y10904);the Hainan Academician Innovation Platform(HD-YSZX-202003,HD-YSZX202004);the Hainan University Startup Fund(KYQD(ZR)1866);Hainan Provincial Natural Science Foundation of China(322RC573),and Hainan Provincial Natural Science Foundation of China(321QN184)。
The sesquiterpene alpha-bisabolol is the predominant active ingredient in essential oils that are highly valued in the cosmetics industry due to its wound healing,anti-inflammatory,and skin-soothing properties.Alpha-b...
关键词:alpha-bisabolol epigenetic regulation natural variation 
SnoRNP is essential for thermospermine-mediated development in Arabidopsis thaliana被引量:2
《Science China(Life Sciences)》2023年第1期2-11,共10页Xilong Li Zongyun Yan Meiling Zhang Jiayin Wang Peiyong Xin Shujing Cheng Liquan Kou Xiaoting Zhang Songlin Wu Jinfang Chu Chengqi Yi Keqiong Ye Bing Wang Jiayang Li 
supported by the National Natural Science Foundation of China(31788103,32122012,32100221,91940302,31430024);the Strategic Priority Research Program of Chinese Academy of Sciences(XDA24040202);the Chinese Academy of Sciences Youth Innovation Promotion Association(2019099);the CAS Key Technology Talent Program(2017)。
Polyamines have been discovered for hundreds of years and once considered as a class of phytohormones.Polyamines play critical roles in a range of developmental processes.However,the molecular mechanisms of polyamine ...
关键词:polyamines thermospermine SNORNP pseudouridylation 2’-O-methylation Arabidopsis thaliana 
NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry被引量:2
《Science China(Life Sciences)》2022年第2期341-361,共21页Guoli Li Bingqian Su Pengfei Fu Yilin Bai Guangxu Ding Dahua Li Jiang Wang Guoyu Yang Beibei Chu 
Viruses utilize cellular lipids and manipulate host lipid metabolism to ensure their replication and spread.Therefore,the identification of lipids and metabolic pathways that are suitable targets for antiviral develop...
关键词:broad-spectrum antiviral NPC inhibition CCP dynamics viral entry 
Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish
《Science China(Life Sciences)》2021年第12期2186-2201,共16页Jiakui Chen Gaofei Li Junwei Lian Ning Ma Zhibin Huang Jianchao Li Zilong Wen Wenqing Zhang Yiyue Zhang 
supported by the National Key Research and Development Program of China(2018YFA0800200);the National Natural Science Foundation of China(31922023);China Postdoctoral Science Foundation(2018M643071);Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(2019);the Fundamental Research Funds for the Central Universities(2019ZD54 and 2019MS131)。
Hematopoietic stem and progenitor cells(HSPCs)are able to self-renew and can give rise to all blood lineages throughout their lifetime,yet the mechanisms regulating HSPC development have yet to be discovered.In this s...
关键词:Slc20a1b HSPC ZEBRAFISH 
FHA domain of AGGF1 is essential for its nucleocytoplasmic transport and angiogenesis被引量:5
《Science China(Life Sciences)》2021年第11期1884-1894,共11页Cui-Fang Zhang Han-Ming Wang Andong Wu Yang Li Xiao-Li Tian 
This work was supported by grants from the National Natural Science Foundation of China(30730047,81070262,81130003 and 81630034).
Angiogenic factor with G-patch and FHA domains 1(AGGF1) exhibits a dynamic distribution from the nucleus to the cytoplasm in endothelial cells during angiogenesis, but the biological significance and underlying mechan...
关键词:AGGF1 nucleocytoplasmic transport ANGIOGENESIS FHA domain 14-3-3α/β 
The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD+ levels被引量:1
《Science China(Life Sciences)》2021年第11期1929-1948,共20页Chengchi Fang Xiaoni Gan Chengjun Zhang Shunping He 
This project is supported by the Pilot projects(XDB13020100);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB31000000);the National Natural Science Foundation of China(NSFC,31601859).
The origination of new genes is important for generating genetic novelties for adaptive evolution and biological diversity.However, their potential roles in embryonic development, evolutionary processes into ancient n...
关键词:new chimeric genes essential function NAD^(+)rate-limiting enzyme coevolution 
MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean被引量:8
《Science China(Life Sciences)》2021年第9期1533-1545,共13页Xiaolong Fang Xiaoyuan Sun Xiangdong Yang Qing Li Chunjing Lin Jie Xu Wenjun Gong Yifan Wang Lu Liu Limei Zhao Baohui Liu Jun Qin Mengchen Zhang Chunbao Zhang Fanjiang Kong Meina Li 
supported by the National Natural Science Foundation of China(32072084,31871648,and 31971969)。
Male sterility is an essential trait in hybrid seed production,especially for monoclinous and autogamous food crops.Soybean male-sterile ms1 mutant has been known for more than 50 years and could be instrumental in ma...
关键词:SOYBEAN male sterility MS1 KINESIN CYTOKINESIS hybrid breeding 
A zebrafish-specific chimeric gene evolved essential developmental functions:discussion of conceptual significance
《Science China(Life Sciences)》2021年第5期840-842,共3页Manyuan Long 
Since the early 1990s,it has been known that new genes originate anytime in evolution in any organisms since the remote past billion years ago(BYA)(Long and Langley,1993;Long et al.,2013).It is also widely accepted th...
关键词:FISH PARENTAL 
Ribosome biogenesis gene DEF/UTP25 is essential for liver homeostasis and regeneration被引量:2
《Science China(Life Sciences)》2020年第11期1651-1664,共14页Weidong Huang Feng Chen Quanxin Ma Jiaojiao Xin Jiaqi Li Jun Chen Bin Zhou Minli Chen Jun Li Jinrong Peng 
supported by the National Key Research and Development Program of China (2018YFA0800502)。
Hepatocytes are responsible for diverse metabolic activities in a liver. Proper ribosome biogenesis is essential to sustain the function of hepatocytes. There are approximately 200 factors involved in ribosome biogene...
关键词:HOMEOSTASIS ORGANS INFLAMMATION 
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