supported by the Science Technology and Innovation Commission of Shenzhen(JCYJ20210324115607021);the National Natural Science Foundation of China(32300068,32270196,91951204,32200155,32200053,and 32300060).
Antibiotic-resistant bacterial pathogens pose substantial biosafety and health hazards,leading to millions of deaths each year.The evolution of bacterial virulence factors is mainly propelled by horizontal gene transf...
funded by National Key Research and Development Program of China(2022YFD2100104);Science and Technology Research Program of the Liaoning Department of Education(J2020044);Shaanxi Key Research and Development project(2019SF-259);LiaoNing Revitalization Talents Program(XLYC1807220).
Akkermansia muciniphila is one of the commensals residing within the mammalian gut and co-evolving with the host.Numerous studies have demonstrated the benefits of A.muciniphila in ameliorating metabolic disorders,whi...
supported by Brain Korea (BK)21 Plus Project (4299990913942)funded by the Korean Government,Korea;the Collabo Project funded by the Ministry of SMEs and Startups (C1016120-01-02);the National Research Foundation of Korea (NRF) (2018007551)。
Slightly acidic electrolyzed water(SAEW)has proven to be an efficient and novel sanitizer in food and agriculture field.This study assessed the efficacy of SAEW(30 mg/L)at 40℃on the inactivation of foodbome pathogens...
supported by the National Natural Science Foundation of China(Grant No.32271386);Zhejiang Engineering Research Center for Tissue Repair Materials(Grant No:WIUCASZZXF21001);Wenzhou Science and Technology Major Project(ZY2022028);Wenzhou Science and Technology Project(Y20220142);the seed grants from the Wenzhou Institute,University of Chinese Academy of Sciences(WIUCASQD2020013,WIUCASQD2021030);the Opening Project of State Key Laboratory of High Performance Ceramics and Superfine Microstructure(Grant Nos:SKL-202112SIC,SKL202213SIC);the founding from First Affiliated Hospital of Wenzhou Medical University.
Infected wounds pose a significant global health challenge due to the persistence of bacterial biofilms and limited tissue self-repair.Nitric oxide(NO)functions as a potent antimicrobial agent,demonstrating a dual cap...
The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China(grant Nos.82272067,81971678,22107123,and M-0696);Natural Science Foundation of Hunan Province(grant Nos.2022JJ80052,2022JJ40656,20231120077,China);Scientific Research Fund of Hunan Provincial Education Department(22B0009,China);the Central South University Innovation-Driven Research Program(2023CXQD004,China).
Bacterial biofilm-associated infection was one of the most serious threats to human health. However, effective drugs for drug-resistance bacteria or biofilms remain rarely reported. Here, we propose an innovative stra...
Protein misfolding and aggregation into amyloid fibrils is the main pathological hallmark of neurodegenerative diseases,including Alzheimer’s,Parkinson’s,Huntington’s,and prion diseases(Chiti and Dobson,2017).These...
supported by the National Natural Science Foundation of China(82172078);the National Key Research and Development Program of China(2022YFB3804500);the Academic Promotion Program of Shandong First Medical University(2019QL010);the Shenzhen Science and Technology Program(RCJC20210706092010008);the Shenzhen Basic Research Program(SGDX20201103093600004);the Special Funds for the Development of Strategic Emerging Industries in Shenzhen(20180309154519685);the Funding from Shanghai Key Laboratory of Hydrogen Science&Center of Hydrogen Science,Shanghai Jiao Tong University,China。
It is a great challenge to effectively eradicate biofilm and cure biofilm-infected diseases because dense extracellular polymeric substance matrix prevents routine antibacterial agents from penetrating into biofilm.H_...
Objective: This study focused on the antibacterial and anti-proliferative activity of extracts from Carica papaya and Cocos nucifera roots. Methodology: The minimum inhibitory concentration and the minimum bactericida...