云南高校图书馆联盟文献共享服务平台- INSULIN

INSULIN_RESISTANCE: 作品数：774被引量：3602H指数：25; 导出分析报告; 相关作者：李雪飞张思仲刘合焜陈素云田浩明更多>>; 相关机构：南京医科大学北京大学第一医院北京大学四川大学华西医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>

Bakuchiol ameliorates glycolipid homeostasis by reducing inflammation: 《Food Science and Human Wellness》2024年第6期3159-3170,共12页Zhenhua Liu Xiaoqing Xu Zhenhua Liang Yixiao Chen Qiuyi Wang Wenyi Kang Yan Zhang Bin Cong; supported by National Key R&D Program of China(2022YFF1100300);the Central Guidance on Local Science and Technology Development Found of Shenzhen,China(2021Szvup030).; Inflammatory stimulation plays a significant role in the development and worsening of insulin-resistant diabetes.Therefore,it is crucial to identify therapeutic agents that can alleviate insulin resistance by targetin...; 关键词：BAKUCHIOL DIABETES Insulin resistance PROTEOMIC INFLAMMATION

Effects of axylitol-casein complex on insulin resistance and gut microbiota composition in high-fat-diet+streptozotocin-induced type 2 diabetes mellitus mice: 《Food Science and Human Wellness》2024年第5期2741-2753,共13页Fanhua Kong Juan Zhang Shimo Kang Xinyu Shen Aicheng Liu Yan Zheng Junhua Shao Xiqing Yue; supported by the “Thirteenth Five Year” National Science and Technology Plan Project of China (2018YFC1603703,2018YFC1604302);National Natural Science Foundation of China (2013BAD18B03);Shenyang Technological Innovation Project (Y170-028);LiaoNing Revitalization Talents Project (XLYC1902083); This study investigated the effects of a xylitol-casein non-covalent complex(XC)on parameters related to type 2 diabetes mellitus(T2DM),in addition to related changes in gut microbiome composition and functions.High-f...; 关键词：Xylitol-casein complex Type 2 diabetes mellitus Insulin resistance Gut microbiota

Palmitoleic acid on top of HFD ameliorates insulin resistance independent of diacylglycerols and alters gut microbiota in C57BL/6J mice: 《Food Science and Human Wellness》2024年第2期856-868,共13页Qijian Liang Yan Zheng Fanli Meng Xiaofan Jiang Qingcai Zhen Zhongting Lu Shixiu Zhang Lei Du Hao Wu Xin Guo; by National Natural Science Foundation of China(81803224);Young Scholars Program of Shandong University(2018WLJH33)to X.G.;National Natural Science Foundation of China(81973031);Cheeloo Young Scholar Program of Shandong University(21320089963054)to H.W.;Young Scholars Program of Shandong University(2018WLJH34);the Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology(LMDBKF-2019-05)to L.D.; With the prevalence of obesity and obesity-related metabolic syndrome,such as insulin resistance in recent years,it is urgent to explore effective interventions to prevent the progression of obesity-related metabolic ...; 关键词：Palmitoleic acid High fat diet Insulin resistance Gut microbiota

Kaempferol improves glucose uptake in skeletal muscle via an AMPK-dependent mechanism: 《Food Science and Human Wellness》2023年第6期2087-2094,共8页William T.Moore Jing Luo Dongmin Liu; partially supported by grants from Diabetes Action Research and Education Foundation。; Insulin resistance is a hallmark of type-2 diabetes(T2D)pathogenesis.Because skeletal muscle(SkM)is the major tissue for insulin-mediated glucose disposal,insulin resistance in SkM is considered a major risk factor fo...; 关键词：KAEMPFEROL Skeletal muscle AMPK AKT Insulin resistance

Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin: 《Food Science and Human Wellness》2023年第6期2095-2110,共16页Xiaoyu Chen Hongyuan Zhao Fanqiang Meng Libang Zhou Zhaoxin Lu Yingjian Lu; supported by the National Natural Science Foundation of China(32072182)。; Type 2 diabetes mellitus(T2DM)is associated with liver dysfunction and intestinal dysbiosis.Bioactive peptides(BAPs)have been reported to ameliorate T2DM by preventing oxidative damage to the liver.Bacillus amylolique...; 关键词：SURFACTIN Type 2 diabetes mellitus(T2DM) Insulin resistance Gut microbiota Glucose metabolism

Network pharmacology-based screening of the active ingredients and mechanisms of Cymbaria daurica against diabetes mellitus: 《Food Science and Human Wellness》2023年第6期2001-2013,共13页Ruyu Shi Dongxue Chen Mingyue Ji Baochang Zhou Ziyan Zhang Chunhong Zhang Minhui Li; funded by the National Natural Science Foundation of China(81760776);the Natural Science Foundation of Inner Mongolia Autonomous Region(2018ZD13,2018LH08082,2019MS08208).; Cymbaria daurica L.has a long history as a folk medicine and tea for the treatment of diabetes.However,the biological activity and mechanism of its hypoglycemic effect have not been fully elucidated.In this study,the ...; 关键词：Cymbaria daurica L.Diabetes mellitus Network pharmacology Insulin resistance Molecular docking PI3K-Akt signaling pathway

Lignans from Patrinia scabiosaefolia improve insulin resistance by activating PI-3K/AKT pathway and promoting GLUT4 expression: 《Food Science and Human Wellness》2023年第6期2014-2021,共8页Zhenhua Liu Mengke Wang Lijun Meng Yixiao Chen Qiuyi Wang Yan Zhang Xuefeng Xi Wenyi Kang; funded by National Key R&D Program of China(2022YFF1100300);National Natural Science Foundation of China(31900292);Science and Technology Development Program of Henan Province(212102110469,222102520035);Research on Precision Nutrition and Health Food,Department of Science and Technology of Henan Province(CXJD2021006).; Patrinia scabiosaefolia,is used as wild vegetable in China for more than 2000 years,with a variety of pharmacological activities,including anti-inflammatory,anti-tumor and hypoglycemic.Based on our ongoing research on...; 关键词：Patrinia scabiosaefolia Insulin resistance Patrinian A 7R 7’R 8S 8’S-(+)-neo-olivil-4-O-β-D-glucopyranoside

Ginsenoside F1 administration promotes UCP1-dependent fat browning and ameliorates obesity-associated insulin resistance: 《Food Science and Human Wellness》2023年第6期2061-2072,共12页Yuhan Meng Weili Li Chenxing Hu Si Chen Haiyang Li Feifei Bai Lujuan Zheng Ye Yuan Yuying Fan Yifa Zhou; supported by the National Natural Science Foundation of China[31872674];the Jilin Talent Development Foundation Grant[20200301018RQ];the Fundamental Research Funds for the Central Universities[CGZH202206].; Obesity-induced type 2 diabetes is mainly due to excessive free fatty acids leading to insulin resistance.Increasing thermogenesis is regarded as an effective strategy for hypolipidemia and hypoglycemia.Ginsenoside is...; 关键词：Ginsenoside F1 Uncoupling protein 1 β3-Adrenergic receptor White adipose tissue browning Insulin resistance

Polyphenols and pectin enriched golden kiwifruit (Actinidia chinensis) alleviates high fructose-induced glucolipid disorders and hepatic oxidative damage in rats:in association with improvement of fatty acids metabolism被引量：1: 《Food Science and Human Wellness》2023年第5期1872-1884,共13页Aamina Alim Ting Li Tanzeela Nisar Zeshan Ali Daoyuan Ren Yueyue Liu Xingbin Yang; funded by the National Natural Science Foundation of China (C31901702,and 32072175);the China Postdoctoral Science Foundation (2019M653535,2020T130395);the Fundamental Research Funds for the Central Universities of Shaanxi Normal University in China (GK202003083);the grants of Sci-Tech Innovation Team of Shaanxi Province (2019TD-035);the Development Program for Innovative Research Team of Shaanxi Normal University (GK202101006)。; This study aimed to investigate the protective effects of fleshes from two Actinidia chinensis(ACF), pericarps from two A. chinensis(ACP), and fleshes with pericarps from two A. chinensis(ACFP)on high fructose(HF)-ins...; 关键词：Actinidia chinensis peel Lipid homeostasis Oxidative stress Insulin resistance Hepatocellular injury Fatty acid metabolism

The hypoglycemic potential of phenolics from functional foods and their mechanisms被引量：3: 《Food Science and Human Wellness》2023年第4期986-1007,共22页Oksana Golovinskaia Chin-Kun Wang; Long-term postprandial hyperglycemia is a primary risk factor for developing chronic metabolic diseases such as obesity,type 2 diabetes,and cardiovascular disease.Chronic hyperglycemia induces the glycation of protein...; 关键词：Phenolics Functional foods HYPOGLYCEMIA Insulin resistance Insulin secretion

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