IRRITABLE

作品数:153被引量:1654H指数:17
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相关领域:医药卫生更多>>
相关作者:张声生汪正芳郭前坤魏玮蒋欢欢更多>>
相关机构:首都医科大学附属北京中医医院中华中医药学会中国中医科学院望京医院河北北方学院附属第二医院更多>>
相关期刊:《Psychosomatic Medicine Research》《Chinese Medical Journal》《外科研究与新技术(中英文)》《Precision Medicine Research》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Serotonin transporter and cholecystokinin in diarrhea-predominant irritable bowel syndrome: Associations with abdominal pain, visceral hypersensitivity and psychological performance被引量:15
《World Journal of Clinical Cases》2020年第9期1632-1641,共10页Geng Qin Yu Zhang Shu-Kun Yao 
Supported by the National Key Technology Support Program during “12th Five-Year Plan”period of China,No.2014BAI08B00;the Leapforward Development Program for Beijing Biopharmaceutical Industry(G20),No. Z171100001717008.
BACKGROUND Visceral hypersensitivity and psychological performance are the main pathophysiological mechanisms of irritable bowel syndrome(IBS).Previous studies have found that cholecystokinin(CCK)can enhance colon mov...
关键词:IRRITABLE bowel syndrome Abdominal pain VISCERAL HYPERSENSITIVITY Psychological performance SEROTONIN TRANSPORTER CHOLECYSTOKININ 
Treatment of Visceral Pain Associated with Irritable Bowel Syndrome using Acupuncture: Mechanism of Action
《World Journal of Traditional Chinese Medicine》2019年第4期181-186,共6页Aleksandar Zivaljevic Bin Shi Elisa M.S.Tam Vahideh Toossi 
Research supported by New Zealand College of Chinese Medicine
Irritable bowel syndrome(IBS)is a relatively common condition characterized by abdominal pain,among other symptoms,that significantly impacts the quality of life of IBS patients.Therapeutic treatment of IBS results in...
关键词:ACUPUNCTURE IRRITABLE BOWEL SYNDROME VISCERAL PAIN 
Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel syndrome被引量:10
《World Journal of Gastroenterology》2019年第43期6416-6429,共14页Wen-Xue Zhang Yu Zhang Geng Qin Kai-Min Li Wei Wei Su-Yun Li Shu-Kun Yao 
the National Key Technology Support Program for the “12th Five-Year Plan” of China,No.2014BAI08B00;the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital,No.PYBZ1815
BACKGROUND Fecal metabolites are associated with gut visceral sensitivity,mucosal immune function and intestinal barrier function,all of which have critical roles in the pathogenesis of irritable bowel syndrome(IBS).H...
关键词:FECAL metabolite IRRITABLE bowel syndrome Amino ACIDS Organic ACIDS Short chain fatty ACIDS VISCERAL HYPERSENSITIVITY 
Effect of the interleukin 10 polymorphisms on interleukin 10 production and visceral hypersensitivity in Chinese patients with diarrhea-predominant irritable bowel syndrome被引量:6
《Chinese Medical Journal》2019年第13期1524-1532,共9页Shi-Wei Zhu Zuo-Jing Liu Qing-Hua Sun Li-Ping Duan 
grants from the National Natural Science Foundation of China(No.81670491);National“Twelfth Five-Year”Plan for Science and Technology of China(No.2012BAI06B02).
Background:Irritable bowel syndrome (IBS),a functional gastrointestinal disorder,is characterized by cytokine imbalance.Previously,decreased plasma interleukin 10 (IL-10) level was reported in patients with IBS,which ...
关键词:IRRITABLE BOWEL syndrome INTERLEUKIN 10 POLYMORPHISMS VISCERAL HYPERSENSITIVITY Depression 
Neonatal Maternal Deprivation Followed by Adult Stress Enhances Adrenergic Signaling to Advance Visceral Hypersensitivity被引量:6
《Neuroscience Bulletin》2019年第1期4-14,共11页Wan-Jie Du Shufen Hu Xin Li Ping-An Zhang Xinghong Jiang Shan-Ping Yu Guang-Yin Xu 
supported by grants from the National Natural Science Foundation of China(81471137,31730040,and 81500952);the Priority Academic Program Development of Jiangsu Higher Education Institutions of China
The pathophysiology of visceral pain in patients with irritable bowel syndrome remains largely unknown.Our previous study showed that neonatal maternal deprivation(NMD) does not induce visceral hypersensitivity at the...
关键词:IRRITABLE bowel syndrome DORSAL root GANGLION NOREPINEPHRINE VISCERAL pain STRESS 
Increased expression of brain-derived neurotrophic factor is correlated with visceral hypersensitivity in patients with diarrheapredominant irritable bowel syndrome被引量:17
《World Journal of Gastroenterology》2019年第2期269-281,共13页Yu Zhang Geng Qin De-Rong Liu Yan Wang Shu-Kun Yao 
Supported by the National Key Technology Support Program during "12th Five-Year Plan"Period of China,No.2014BAI08B00;the Leapforward Development Program for Beijing Biopharmaceutical Industry(G20),No.Z171100001717008
BACKGROUND Visceral hypersensitivity is considered to play a vital role in the pathogenesis of irritable bowel syndrome(IBS). Neurotrophins have drawn much attention in IBS recently. Brain-derived neurotrophic factor(...
关键词:IRRITABLE bowel syndrome DIARRHEA BRAIN-DERIVED NEUROTROPHIC factor VISCERAL HYPERSENSITIVITY Nerve growth 
Increased intestinal mucosal leptin levels in patients with diarrhea-predominant irritable bowel syndrome被引量:10
《World Journal of Gastroenterology》2018年第1期46-57,共12页De-Rong Liu Xiao-Juan Xu Shu-Kun Yao 
Supported by National key Technology Support Program during the"12th Five-Year Plan"Period of China,No.2014BAI08B02
AIM To measure the leptin levels in patients with diarrheapredominant irritable bowel syndrome(IBS-D) and analyze the relationship of leptin with clinical features, visceral sensitivity, mast cells, and nerve fibers. ...
关键词:Leptin IRRITABLE bowel syndrome MAST cells DIARRHEA VISCERAL HYPERSENSITIVITY 
Irritable bowel syndrome symptom severity improves equally with probiotic and placebo被引量:7
《World Journal of Gastroenterology》2016年第48期10631-10642,共12页Anna Lyra Markku Hillila Teppo Huttunen Sofia Mannikko Mikko Taalikka Julia Tennila Anneli Tarpila Sampo Lahtinen Arthur C Ouwehand Lea Veijola 
AIM To determine the effects of Lactobacillus acidophilus NCFM on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS In this randomized triple-blind trial, adult IBS volunteerswho were recruited ...
关键词:IRRITABLE BOWEL syndrome Functional BOWEL disorder Symptom questionnaire Quality of life VISCERAL PAIN Abdominal PAIN Lactobacillus ACIDOPHILUS Probiotic Intervention 
Visceral hypersensitive rats share common dysbiosis features with irritable bowel syndrome patients被引量:11
《World Journal of Gastroenterology》2016年第22期5211-5227,共17页Xiao-Yan Zhou Ming Li Xia Li Xin Long Xiu-Li Zuo Xiao-Hua Hou Ying-Zi Cong Yan-Qing Li 
Supported by National Natural Science Foundation of China,No.81330012 and No.81170352
AIM: To evaluate gut microbial dysbiosis in two visceral hypersensitive models in comparison with irritable bowel syndrome(IBS) patients and to explore the extent to which these models capture the dysbiosis of IBS pat...
关键词:Animal model IRRITABLE BOWEL syndrome Microbiota PYROSEQUENCING 16S rRNA gene 
Preinduced intestinal HSP70 improves visceral hypersensitivity and abnormal intestinal motility in PI-IBS mouse model被引量:8
《Asian Pacific Journal of Tropical Medicine》2016年第3期297-300,共4页Cheng Lan Xiao-Ning Sun Xu-Chun Zhou Bo Yang Bai-Li Huang Tao-Zhi Deng Zhou-Tao He Xiang-Yang Han 
supported by Natural Science Foundation of China Grant(No.81160057):International Science and Technique Corporation Foundation of Hainan Province Grant(No.KJHZ2013-14)
Objective:To investigate the impact of the preinduced intestinal heat shock protein 70(HSP70)on the visceral hypersensitivity and abnormal intestinal motility in a post-infectious irritable bowel syndrome(PI-IBS) mous...
关键词:Post-infectious IRRITABLE bowel syndrome Heat shock protein 70 PROINFLAMMATORY cytokine VISCERAL HYPERSENSITIVITY INTESTINAL MOTILITY 
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