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作品数：340被引量：594H指数：12
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相关领域：自动化与计算机技术医药卫生更多>>
相关作者：杨乃定姜继娇李保昆李志明赵建章更多>>
相关机构：西北工业大学南京大学重庆本木科技有限公司大连理工大学更多>>
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  • 期刊=Neural Regeneration Researchx
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Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress
《Neural Regeneration Research》2026年第1期333-345,共13页Yumei Liao Qinghua Zhang Qiaoyun Shi Peng Liu Peiyun Zhong Lingling Guo Zijian Huang Yinghui Peng Wei Liu Shiqing Zhang István Adorján Yumi Fukuzaki Eri Kawashita Xiao-Qi Zhang Nan Ma Xiaoshen Zhang Zoltán Molnár Lei Shi 
supported in part by the National Key Research&Development Program of China,No. 2022YFA1104900 (to LS);the National Natural Science Foundation of China,Nos. 82371175, 82071535 (both to LS), 82101614 (to YP);the International Science and Technology Cooperation Projects of Guangdong Province,No. 2023A0505050121 (to LS);Guangdong Basic and Applied Basic Research Foundation,Nos. 2022B1515130007 (to LS), 2023A1515030012 (to SZ), 2022A1515010666 (to WL);the Science and Technology Program of Guangzhou,Nos. 202102070001 (to LS), 202201010041 (to YP);Shenzhen Basic Research Grant,Nos. JCYJ20200109140414636, JCYJ20230807145103007 (both to WL);awarded a Royal Society Newton Advanced Fellowship,No. AOMS-NAF0051003;in collaboration with Zoltán Molnár,Department of Physiology,Anatomy and Genetics,University of Oxford (2017–2021)。
Neuroserpin, a secreted protein that belongs to the serpin superfamily of serine protease inhibitors, is highly expressed in the central nervous system and plays multiple roles in brain development and pathology. As a...
关键词：endoplasmic reticulum stress ischemia-reperfusion injury NEURON neuronal apoptosis NEUROPROTECTION NEUROSERPIN protein synthesis secretory protein stroke transcriptomic analysis 
Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin
《Neural Regeneration Research》2025年第5期1445-1454,共10页Meifeng Zheng Borui Zhang Sonata S Y Yau Kwok-Fai So Li Zhang Haining Ou 
supported by STI2030-Major Projects,No.2022ZD0207600(to LZ);the National Natural Science Foundation of China,Nos.32070955(to LZ),U22A20301(to KFS);the Natural Science Foundation of Guangdong Province,No.2021A1515012197(to HO);Guangzhou Core Medical Disciplines Project,No.2021-2023(to HO);Key Research and Development Plan of Ningxia Hui Automomous Region,No.2022BEG01004(to KFS);Science and Technology Program of Guangzhou,China,No.202007030012(to KFS and LZ)。
Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy.Physical exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitatio...
关键词：ADIPONECTIN cerebral ischemia exercise pre-conditioning HIPPOCAMPUS memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise 
Injury/ischemia-induced stem cells: up-to-date knowledge and future perspectives for neural regeneration
《Neural Regeneration Research》2025年第3期797-798,共2页Takayuki Nakagomi 
partially supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (15K06723;18K07380);the Japan Agency for Medical Research and Development (AMED) (21nk0101538h0002) (to TN)。
Brain injuries like ischemic stroke induce endogenous stem cell production. Although the precise traits of stem cells in pathological brains remain unclear, we previously demonstrated that injury/ischemia-induced stem...
关键词：ISCHEMIA INJURIES 
Adenosine A_(2A)receptor blockade attenuates excitotoxicity in rat striatal medium spiny neurons during an ischemic-like insult
《Neural Regeneration Research》2024年第2期255-257,共3页Elisabetta Coppi Federica Cherchi Alasdair J.Gibb 
supported by University of Florence RICATEN 2023 to EC.Grant/Award Numbers 58514_Internazionalizzazione;University of Florence,to EC.Parkinson’s UK,Grant/Award Number:H-0902 to AJG;Wellcome Trust,Grant/Award Number:0926/Z/10/Z to AJG。
During brain ischemia,excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage.Indeed,anoxic depolarization,consisting of massive neuronal depolarization due to the loss of membra...
关键词：adenosine A_(2A)receptors anoxic depolarization brain ischemia glutamate excitotoxicity medium spiny neurons oxygen and glucose deprivation 
TP53-induced glycolysis and apoptosis regulator alleviates hypoxia/ischemia-induced microglial pyroptosis and ischemic brain damage被引量：13
《Neural Regeneration Research》2021年第6期1037-1043,共7页Lan-Lan Tan Xiao-Lu Jiang Li-Xiao Xu Gen Li Chen-Xi Feng Xin Ding Bin Sun Zheng-Hong Qin Zu-Bin Zhang Xing Feng Mei Li 
supported by the National Natural Science Foundation of China,Nos.81872845(to ML),81771625(to XF);the Natural Science Foundation of Jiangsu Province of China,No.BK20180207(to ML);Jiangsu Provincial Medical Youth Talent of China,No.QNRC2016762(to ML);the Pediatric Clinical Center of Suzhou City of China,No.Szzx201504(to XF);Postgraduate Research&Practice Innovation Program of Jiangsu Province of China,No.KYCX19_1998(to LLT);Jiangsu Government Scholarship for Overseas Studies of China,No.JS-2017-127(to ML);the Fifth Batch of Gusu Health Talent Plan of China(to ML).
Our previous studies have demonstrated that TP53-induced glycolysis and apoptosis regulator(TIGAR)can protect neurons after cerebral ischemia/reperfusion.However,the role of TIGAR in neonatal hypoxic-ischemic brain da...
关键词：hypoxic-ischemic brain damage in vitro in vivo microglia NADPH PYROPTOSIS ROS TIGAR 
Early constraint-induced movement therapy affects behavior and neuronal plasticity in ischemia-injured rat brains被引量：14
《Neural Regeneration Research》2019年第5期775-782,共8页Xi-Hua Liu Hong-Yan Bi Jie Cao Shuo Ren Shou-Wei Yue 
supported by the Natural Science Foundation of Shandong Province of China,No.2014ZRB14502(to XHL)
Constraint-induced movement therapy is an effective rehabilitative training technique used to improve the restoration of impaired upper extremity movement after stroke. However, whether constraint-induced movement the...
关键词：NERVE REGENERATION ischemic stroke rehabilitation constraint-induced movement therapy NERVE growth factors functional recovery neuronal plasticity real time-polymerase chain reaction western BLOT assay rats neural REGENERATION 
Effects of minocycline on learning and memory of mice following ischemic-hypoxic cerebral injuries被引量：2
《Neural Regeneration Research》2012年第2期114-118,共5页Hongling Fan Yuanyin Zheng Lijuan Xu Zhichao Zhong Shining Cai Shuling Zhang Quanzhong Chang 
supported by the National Natural Science Foundation of China, No. 81160157;Key Program of the Science and Technology Department of Guizhou Province, No. SY20093075
An ischemic-hypoxic animal model was established using right common carotid artery occlusions and inhalation of low concentrations of oxygen in mice. At 10 days after the ischemic-hypoxic injuries, saline-treated mice...
关键词：MINOCYCLINE ischemic-hypoxic cerebral injury learning and memory cognition 
Effects of Rubus parvifolius L. on neuronal apoptosis and expression of apoptosis-related proteins in a rat model of focal cerebral ischemic-reperfusion injury被引量：1
《Neural Regeneration Research》2008年第7期742-746,共5页Lirong Xu Jisheng Wang Huizhi Li Zongyin Qiu Yongpeng Xia Lingyan Ren 
the Chongqing Science and Technology Commission Grant,No.2004-27
BACKGROUND： Studies have shown that the Rubus parvifolius L. （RP） plant extract exhibits protective effects on cerebral ischemia. This effect is reflected in altered ischemic neuronal apoptosis and associated prote...
关键词：cerebral ischemia/reperfusion apoptosis BCL-2/BAX 
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