National Natural Science Foundation of China(No.82020108028)
To the Editor:Stroke is a major cause of death and longterm serious disability in adults worldwide.Hypertension is the most important modifiable risk factor for primary and secondary prevention of stroke.[1]Even a mod...
supported by a grant from the National Natural Science Foundation of China(No.82020108028)
To the Editor:Hypertension is an important risk factor for the incidence and prognosis of diabetes and ischemic stroke.Both diabetes and ischemic stroke are common disorders that often occur together,and up to approxi...
National Key Research and Development Program of China(No.2020YFC2005000);Key Research and Development Program of Hunan province(No.2020WK2008);science and technology innovation Program of Hunan Province(No.2020RC5002);Natural Science Foundation of Hunan Province(Nos.2022JJ30070,2021JJ31130 and 2021JJ31057);Project of Health Commission of Hunan Province(Nos.A202303050036 and 202104101009);"Yiluqihang Shenmingyuanyang"medical development and Scientific Research Fund project on Kidney Diseases(No.SMYY20220301001)
Background:Ischemic acute kidney injury(AKI)is a common syndrome associated with considerable mortality and healthcare costs.Up to now,the underlying pathogenesis of ischemic AKI remains incompletely understood,and sp...
supported by the National Key R&D Program of China(2017YFC1308400);the National Natural Science Foundation(81371289);and the Beijing Natural Science Foundation(7212047);and Capital Medical Development Scientific Research Fund(2022-2-2015).
Background: Long-term remote ischemic conditioning (RIC) has been proven to be beneficial in multiple diseases, such as cerebral and cardiovascular diseases. However, the hyperacute and acute effects of a single RIC s...
supported by grants from the Ministry of Science and Technology of the People’s Republic of China(No.2015BAI12B04);the National Natural Science Foundation of China(No.31672375);Beijing Municipal Science and Technology Commission(D151100002015001);Beijing Natural Science Foundation(7182049);Basic-Clinical Research Cooperation Funding of Capital Medical University(17JL34);Beijing Municipal Administration of Hospitals’Youth Programme(QML20160501)。
Thrombolytic therapy within 4.5 h from symptom onset is a recognized effective and standard therapy for acute ischemic stroke(AIS),but some patients still have a poor clinical outcome.The evaluation and control of pre...
This research was funded by a grant of the ULM-PUHSC Joint Institute for Translational and Clinical Research(No.PKU2017ZC001-5).
Primary membranous nephropathy(PMN)is the most common cause of nephrotic syndrome in adults.Most patients with PMN have circulating immunoglobulin G4 autoantibody to the podocyte membrane antigen phospholipase A2 rece...
Background: Both cortical and cortical-subcortical (cortex-involved) lesions are typically associated with embolic stroke, of which atrial fibrillation (AF) is the common cause. The aim of this study was to find out t...
Objective: The 3-N-butylphthalide (NBP) comprises one of the chemical constituents of celery oil. It has a series of pharmacologic mechanisms including reconstructing microcirculation, protecting mitochondrial functio...
Background:High on-treatment platelet reactivity (HTPR) has been suggested as a risk factor for patients with ischemic vascular disease.We explored a predictive model of platelet reactivity to clopidogrel and the rela...
grants from the Science and Technology Project (No.2011B080701029);Natural Science Foundation (No.2016A030313303) from the Department of Science and Technology of Guangdong province.
Background:Endothelial dysfunction,the initial pathogenic factor in atherosclerosis,can be alleviated via transient limb ischemia.We observed the effects of regular transient limb ischemia (RTLI) on atherosclerosis in...