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Optical clearing agent combined with hemoporfin-mediated photodynamic therapy for improved efficacy of port-wine stain patients:A pilot study
《Chinese Medical Journal》2024年第24期3145-3147,共3页Jingjing Wen Yamin Zhang Zhen Cai Congcong Wang Jinjin Zhu Lianbin Zhang Jintao Zhu Yan Li Juan Tao 
supported by grants from the National Natural Science Foundation of China(Nos.82203924,82130089,and 82003366);Key Research Program of Hubei province(No.2021BCA120);China Postdoctoral Science Foundation(No.2022M721265).
To the Editor:Photodynamic therapy(PDT)is an alternative treatment option for port-wine stains(PWSs)and offers several advantages over pulsed dye lasers(PDLs).^([1])However,some patients still experience treatment res...
关键词：PATIENTS CLEARING agent 
Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells被引量：3
《Chinese Medical Journal》2023年第18期2210-2220,共11页Zeyu Wang Weijian Li Xue Wang Qin Zhu Liguo Liu Shimei Qiu Lu Zou Ke Liu Guoqiang Li Huijie Miao Yang Yang Chengkai Jiang Yong Liu Rong Shao Xu’an Wang Yingbin Liu 
supported by grants from the National Natural Science Foundation of China(Nos.3213000192,81874181,and 31620103910);the Science and Technology Commission of Shanghai Municipality(No.20JC1419101).
Background:Gallbladder cancer(GBC)is the most common malignant tumor of biliary tract.Isoliquiritigenin(ISL)is a natural compound with chalcone structure extracted from the roots of licorice and other plants.Relevant ...
关键词：ISOLIQUIRITIGENIN Ferroptosis Gallbladder cancer HMOX1 GPX4 
TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition被引量：3
《Chinese Medical Journal》2023年第7期799-806,共8页Hongxiao Song Qingfei Xiao Fengchao Xu Qi Wei Fei Wang Guangyun Tan 
National Natural Science Foundation,China(Nos.81801563,81901592,and 81801565);the 68th batch of first-class funding from the China Postdoctoral Science Foundation(No.2020M680044);the Natural Science Foundation of Jilin Province,Provincial Joint Fund Bethune Medical Project(Nos.20200201340JC,and 20210101338JC);the International Cooperation Project of Jilin Provincial Science and Technology Department(No.20220402085GH);Jilin University Excellent Young Teacher Training Program,and Bethune Project of Jilin University(Nos.2022B12,and 2018B24)
Background:The hepatitis B virus(HBV)vaccine has been efficiently used for decades.However,hepatocellular carcinoma caused by HBV is still prevalent globally.We previously reported that interferon(IFN)-induced tripart...
关键词：HBX Hepatitis B virus pgRNA RIG-I TRIM25 
Telomerase-mediated immortalization of human vaginal wall fibroblasts derived from patients with pelvic organ prolapse
《Chinese Medical Journal》2023年第5期578-587,共10页Tao Guo Ting Xie Jinghe Lang Zhijing Sun 
National Natural Science Foundation of China(No.81971366);Beijing Natural Science Foundation(No.Z190021);CAMS Innovation Fund for Medical Sciences(No.CIFMS 2020-I2M-C&T-B-043)
Background: Extracellular matrix (ECM) remodeling is the most important pathomechanism of pelvic organ prolapse (POP). Fibroblasts are the key to ECM regulation. The passaging capacity of human vaginal wall fibroblast...
关键词：Pelvic organ prolapse FIBROBLASTS Telomere shortening Cellular senescence 
Indocyanine green-mediated antimicrobial photodynamic therapy as an adjunct to non-surgical periodontal treatment:a systematic review and meta-analysis
《Chinese Medical Journal》2023年第3期376-378,共3页Kai Zhao Weibing Zhang Shaoru Wang Jingjing Liu Xinjuan Yu Zhenggang Chen 
To the Editor:Chronic periodontitis has been defined as a slowly progressive disease.Scaling and root planning(SRP)provides a satisfactory prognosis in most cases.However,due to the complex anatomy under gingiva,non-s...
关键词：ANATOMY TREATMENT cyanine 
Low Shear Stress Regulating Autophagy Mediated by the p38 Mitogen Activated Protein Kinase and p53 Pathways in Human Umbilical Vein Endothelial Cells被引量：3
《Chinese Medical Journal》2018年第9期1132-1133,共2页Hui-Zhen Liu Li Li Shao-Liang Chen Jian-Rui Wei Jun-Xia Zhang Jia Liu Jie-Wen Guo Xin-Liang Qu Peng Chu 
This study was supported by grants from the Natural Science Foundation of Guangdong Province （No. 2016A030313430）, the Scientific and Technological Program of Guangzhou City （No. 201510010024）, and the Natural Science Foundation of Guangdong Province （No. 2014A030310049）.
To the Editor：Autophagy is reported to play a critical role in low shear stress （LSS）-induced endothelial cell injury and the formation of atherosclerotic plaques.[1] However,the corresponding mechanisms remain unc...
Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer＇s Disease被引量：25
《Chinese Medical Journal》2017年第24期2978-2990,共13页Xi-Lin Wu Juan Pina-Crespo Yun-Wu Zhang Xiao-Chun Chen Hua-Xi Xu 
This work was supported by grants from the National Natural Science Foundation of China （No. 81671352, 91232709）, the National Key Project of Research and Development Plan （No. 2016YFC1306404）, the National Institute of Health （No. R21 AG048519, R01 AG021173, R01 AG038710, R01 AG044420, R01 NS046673, RF1 AG056130, and RF1 AG056114）, the Tanz Family Fund as well as scholarship from China Scholarship Council （No. 201608350068）.
Objective：To review recent research advances on tau,a major player in Alzheimer＇s disease （AD） pathogenesis,a biomarker for AD onset,and potential target for AD therapy.Data Sources：This review was based on a com...
关键词：Alzheimer＇s Disease BIOMARKER lmmunotherapy Tau Imaging Tau Protein Transcellular Propagation 
Relation of Biochemical Parameters with Flow-mediated Dilatation in Patients with Metabolic Syndrome
《Chinese Medical Journal》2017年第13期1564-1569,共6页Nurver Turfaner Sipahioglu Barls Ilerigelen Zeynep B. Gungor Gulsel Ayaz Hakan Ekmekci Cigdem Bayram Gurel Gunay Can Huseyin Sonmez Turgut Ulutin Fikret Sipahioglu 
Background： Metabolic syndrome （MetS） is one of the high cardiovascular （CV） situations. Endothelial dysfunction, which is a common finding in patients with MetS, is related with increased CV risk. In patients wi...
关键词：Endothelial Dysfunction Metabolic Syndrome Oxidative Stress SMOKING 
Enhanced integrin-mediated human osteoblastic adhesion to porous amorphous calcium phosphate/poly（L-lactic acid） composite被引量：2
《Chinese Medical Journal》2014年第19期3443-3448,共6页Huang Xin Qi Yiying Li Weixu Shi Zhongli Weng Wenjian Chen Kui He Rongxin 
The present study was supported by grants from the Natural Science Foundation of China （No. 81201414 and No. 81101377）, the Doctoral Fund of the Ministry of Education of China （No. 20100101120132）, and the Natural Science Grants of the Zhejiang Province （No. LQ14H060001）.
Background The initial osteoblastic adhesion to materials characterizes the first phase of cell-material interactions and influences all the events leading to the formation of new bone. In a previous work, we develope...
关键词：amorphous calcium phosphate OSTEOBLAST cell adhesion INTEGRIN 
Lentivirus-mediated RNA interference targeting the ObR gene in human breast cancer MCF-7 cells in a nude mouse xenograft model被引量：6
《Chinese Medical Journal》2012年第9期1563-1570,共8页XUE Rong-quan GU Jun-chao DU Song-tao YU Wei WANG Yu ZHANG Zhong-tao BAI Zhi-gang MA Xue-mei 
This study was supported by a grant from the National Natural Science Foundation of China （No. 30772121） and the Beijing Natural Science Foundation （No. 7092024）.
Background There is a significant association between obesity and breast cancer, which is possibly due to the expression of leptin. Therefore, it is important to clarify the role of leptin/ObR （leptin receptor） sig...
关键词：RNA interference breast neoplasms xenografi model leptin receptor estrogen receptor α vascular endothelial growth factor 
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