One of the leading issues in multiple sclerosis(MS)research is the lack of understanding regarding the triggers of neurodegeneration.While demyelination is a major feature in MS,the degeneration of gray matter neurons...
To stop the progression of Alzheimer's disease in the early stage, it is necessary to identify new therapeutic targets. We examined striatal-enriched phosphatase 61 expression in the brain tissues of 12-month-old APP...
supported by the National Natural Science Foundation of China(No.81271406)
Niemann-Pick disease type C(NPC) is a fatal, neurovisceral lipid storage disease, neuropathologically characterized by cytoplasmic sequestration of glycolipids in neurons, progressive neuronal loss, neurofibrillary ...
In multiple sclerosis, gray matter atrophy is extensive, and cognitive deficits and mood disorders are frequently encountered. It has been conjectured that focal atrophy is associated with emotional decline. However, ...
supported by grants from NHMRC (APP1125796);The Col Bambrick Memorial MND Research Grant;The NTI MND Research Grant;the FightMND Foundation;supported by an NHMRC Senior Research Fellowship APP1118452。
Microglia, the main driver of neuroinflammation, play a central role in the initiation and exacerbation of various neurodegenerative diseases and are now considered a promising therapeutic target. Previous studies on ...