supported by the National Natural Science Foundation of China(32071359,11827803,61227902,and U20A20390);National Key Technology R&D Program(2020YFC0122203);International Joint Research Center of Aerospace Biotechnology and Medical Engineering from Ministry of Science and Technology of China;111 Project(B13003);Research Fund for the Doctoral Program of Higher Education of China(20131102130004);Fundamental Research Funds for the Central Universities.
Cell sheet engineering has been proven to be a promising strategy for cardiac remodeling post-myocardial infarction. However, insufficient mechanical strength and low cell retention lead to limited therapeutic efficie...
The authors graciously acknowledge professor Deling Kong's lab for their assistance with the animal experiments.This project was supported by the National Natural Science Foundation of China(T2288101,32000968,32071359,11827803,and U20A20390);Beijing Natural Science Foundation(M22026);Fundamental Research Funds for the Central Universities,and 111 Project(B13003).
The development of small-diameter vascular grafts that can meet the long-term patency required for implementation in clinical practice presents a key challenge to the research field.Although techniques such as the bra...
This work was supported by the National Natural Science Foundation of China(Grant No.12072055,11872135,U20A20390,U22A20314);Natural Science Foundation of Beijing(Grant No.L212063);the Fundamental Research Funds for the Central Universities,the 111 Project(No.B13003);the National Research Program of China(Grant No.2022YFC2504200);Orthodontic research project of youth clinical research fund of Chinese Stomatological Association(Grant No.CSA-O2020-07);Municipal graduate tutor team construction project(dstd201903).
This study aimed to explore the optimal invisible orthodontic force system during the en-mass distalization of two maxillary molars to minimize the side effect of anchorage loss by changing the direction of the applic...
This work was supported by the National Natural Science Foundation of China(Nos.U20A20390,11827803,and 11302020);the 111 Project(No.B13003).
Mechanical stretch plays an important role in the control of cardiomyocyte behavior,as well as in the study of the mechanisms of cardiovascular function and pathology.The complexity involved in biological systems in v...
The study was supported by National Natural Science Foundation of China(No.12172034,U2241273,11827803,U20A20390);Beijing Municipal Natural Science Foundation(7212205);the 111 project(B13003);the Fundamental Research Funds for the Central Universities.
Irisin,a myokine mainly secreted from contracted skeleton muscle,plays a profound role in bone formation and remodeling.Although irisin has been revealed to elevate bone mass in vivo,details whether there is a dosedep...
support from the National Natural Science Foundation of China(Nos.32171345 and 31771042);the Hebei Provincial Natural Science Foundation of China(No.C2022104003);the Fok Ying Tung Education Foundation(No.141039);the Fund of Key Laboratory of Advanced Materials of Ministry of Education;the International Joint Research Center of Aerospace Biotechnology and Medical Engineering,Ministry of Science and Technology of China,and the 111 Project(No.B13003).
Covalent binding between bioactive substances and materials in different ways can significantly improve the bone inductivity and biological activity of bone repair materials.However,there is a lack of systematic under...
financially supported by the National Natural Science Foundation of China(Nos.12272032,11872097,11827803 and U20A20390);the National Key R&D Program of China(No.2020YFC0122204);the 111 Project(No.B13003).
As the quality of life improves,people pay more and more attention to health.They are concerned about the causes of diseases,and seek better treatments.The most common diseases are biomineralized diseases,four differe...
the financial support from the National Natural Science Foundation of China(No.32122046,12272032,82072082,32101102);the National Key R&D Program of China(No.2020YFC0122204,2018YFA0703100);the Youth Innovation Promotion Association of CAS[No.2019350];the Shenzhen Fundamental Research Foundation[No.JCYJ20210324115814040];the 111 Project(No.B13003).
In the field of regenerative medicine,the importance of 3D bioprinting is self-evident and nonnegligible.However,3D bioprinting technology also requires bioink with excellent performance as support material to fabrica...
support from the National Natural Science Foundation of China(No.32171345);Hebei Provincial Natural Science Foundation of China(No.C2022104003);the Fok Ying Tung Education Foundation(No.141039);the Fund of Key Laboratory of Advanced Materials of Ministry of Education,the International Joint Research Center of Aerospace Biotechnology and Medical Engineering,Ministry of Science and Technology of China;the 111 Project(No.B13003).
The osteochondral defect repair has been most extensively studied due to the rising demand for new therapies to diseases such as osteoarthritis.Tissue engineering has been proposed as a promising strategy to meet the ...
supported by the National Natural Science Foundation of China(Nos.11872097,11827803 and U20A20390);the National Key R&D Program of China(No.2020YFC0122204);the 111 Project(No.B13003).
The bone matrix plays an indispensable role in the human body,and its unique biomechanical and mechanobiological properties have received much attention.The bone matrix has unique mechanical anisotropy and exhibits bo...