《Biomaterials Translational》

作品数:143被引量:92H指数:5
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《Biomaterials Translational》
主办单位:中华医学会
最新期次:2024年4期更多>>
发文主题:BIOMATERIALSTISSUE_ENGINEERINGORGANOIDSHYDROGELANIMAL_MODEL更多>>
发文领域:医药卫生金属学及工艺化学工程理学更多>>
发文基金:国家自然科学基金中国博士后科学基金The Royal Society国家重点基础研究发展计划更多>>
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Organoids:the future of disease modelling and therapeutics
《Biomaterials Translational》2024年第4期335-336,共2页Dongyang Zhou Zhidao Xia Jiacan Su 
In the rapidly advancing field of biomedical research,organoid technology has been a groundbreaking development.Organoids-three-dimensional structures derived from stem cells that replicate key structural and function...
关键词:ORGANS development. BREAKING 
Model construction and clinical therapeutic potential of engineered cardiac organoids for cardiovascular diseases被引量:1
《Biomaterials Translational》2024年第4期337-354,共18页Yongtao Wang Yan Hou Tian Hao Marta Garcia-Contreras Guoping Li Dragos Cretoiu Junjie Xiao 
supported by National Natural Science Foundation of China(No.82302401 to YW);the grant from Science and Technology Commission of Shanghai Municipality(Nos.23410750100,20DZ2255400 and 21XD1421300 to JX);the“Dawn”Program of Shanghai Education Commission(No.19SG34 to JX).
Cardiovascular diseases cause significant morbidity and mortality worldwide.Engineered cardiac organoids are being developed and used to replicate cardiac tissues supporting cardiac morphogenesis and development.These...
关键词:cardiac organoids cardiovascular diseases clinical applications scaffolds SELF-ASSEMBLY 
Progress in spinal cord organoid research:advancing understanding of neural development,disease modelling,and regenerative medicine被引量:1
《Biomaterials Translational》2024年第4期355-371,共17页Ruiqi Huang Yanjing Zhu Haokun Chen Liqun Yu Zhibo Liu Yuchen Liu Zhaojie Wang Xiaolie He Li Yang Xu Xu Yuxin Bai Bairu Chen Rongrong Zhu 
financially supported by the National Science Fund for Distinguished Young Scholars(No.82225027);the National Key Research and Development Program(No.2021YFA1101301);the National Natural Science Foundation of China(Nos.82271419,82202702,82202351,82001308,and 82271418);Shanghai Rising-Star Program(No.22QA1408200).
Stem cell-derived spinal cord organoids(SCOs)have revolutionised the study of spinal cord development and disease mechanisms,offering a three-dimensional model that recapitulates the complexity of native tissue.This r...
关键词:disease modelling NEURODEVELOPMENT regenerative medicine spinal cord organoids stem cells 
Revolutionising oral organoids with artificial intelligence被引量:1
《Biomaterials Translational》2024年第4期372-389,共18页Jiawei Yang Nicholas G.Fischer Zhou Ye 
supported by the IADR Innovation in Oral Care Awards,the Innovation and Technology Fund(No.ITS/307/22);the National Natural Science Foundation of China(NSFC)Young Scientist Fund(No.82401187).
The convergence of organoid technology and artificial intelligence(AI)is poised to revolutionise oral healthcare.Organoids-three-dimensional structures derived from human tissues-offer invaluable insights into the com...
关键词:artificial intelligence BIOPRINTING dental stem cells machine learning oral disease oral organoids 
Skeletal organoids
《Biomaterials Translational》2024年第4期390-410,共21页Chen Zhang Yingying Jing Jianhua Wang Zhidao Xia Yuxiao Lai Long Bai Jiacan Su 
financially supported by National Natural Science Foundation of China(Nos.32471396,82230071,82172098);Integrated Project of Major Research Plan of National Natural Science Foundation of China(No.92249303);Shanghai Committee of Science and Technology(No.23141900600,Laboratory Animal Research Project);Shanghai Clinical Research Plan(No.SHDC2023CRT01);Shanghai Municipal Demonstration Project for Innovative Medical Device Applications(No.23SHS05700);Young Elite Scientist Sponsorship Program by China Association for Science and Technology(No.YESS20230049).
The skeletal system,composed of bones,muscles,joints,ligaments,and tendons,serves as the foundation for maintaining human posture,mobility,and overall biomechanical functionality.However,with ageing,chronic overuse,an...
关键词:APPLICATIONS construction strategies ORGANOIDS skeletal system 
Cardiac organ chip:advances in construction and application
《Biomaterials Translational》2024年第4期411-424,共14页Jun Li Honghao Hou Qian Li Junjie Liu Yunlong Zhao Chaoran Zhao Zhentao Li Leyu Wang Xiaozhong Qiu 
supported by the National Natural Science Foundation of China(Nos.32430057,U21A20173,32201083 and 32071355);the Guangdong Basic and Applied Basic Research Foundation(No.2023B1515120055).
Cardiovascular diseases are a leading cause of death worldwide,and effective treatment for cardiac disease has been a research focal point.Although the development of new drugs and strategies has never ceased,the exis...
关键词:cardiac organ chip DRUG cardiac disease MICROENVIRONMENT microfluidic 
Future perspectives:advances in bone/cartilage organoid technology and clinical potential被引量:1
《Biomaterials Translational》2024年第4期425-443,共19页Jingtao Huang Aikang Li Rongji Liang Xiaohao Wu Shicheng Jia Jiayou Chen Zilu Jiao Canfeng Li Xintao Zhang Jianjing Lin 
supported by National Natural Science Foundation of China(No.82272568);Sanming Project of Medicine in Shenzhen(No.SZSM202211019);Guangdong Basic and Applied Basic Research Foundation(Nos.2023A1515220019&2022A1515220056);“Merro”Young Physician Innovation and Development Project(No.GSKQNJJ-2023-004);Peking University Shenzhen Hospital Scientific Research Fund(No.KYQD2023297).
Bone and cartilage tissues are essential for movement and structure,yet diseases like osteoarthritis affect millions.Traditional therapies have limitations,necessitating innovative approaches.Organoid technology,lever...
关键词:BIOMATERIALS BONE CARTILAGE ORGANOIDS stem cells tissue engineering 
A novel strategy for treating acute liver failure:encapsulated proliferating human hepatocyte organoids被引量:1
《Biomaterials Translational》2024年第4期444-446,共3页Xiangying Meng Aihui Liu Oulayvanh Phangthavong Yi Sun 
Acute liver failure(ALF)is a short-term severe damage to hepatocytes caused by hepatotropic viruses,drug,etc.and accompanied by complications such as multi-organ failure and hepatic encephalopathy.1 The global inciden...
关键词:ACUTE LIMITATIONS annually 
Human cartilage organoids and beyond被引量:1
《Biomaterials Translational》2024年第4期447-450,共4页Kai Dai Jing Wang 
financially supported by the National Natural Science Foundation of China(No.32301123).
In recent years,the field of organoid research has undergone a remarkable transformation,heralding a new era in biomedical science.1,2 This progress is exemplified by the development of an array of sophisticated organ...
关键词:CARTILAGE FRONTIER expanded 
Human foetal brain self-organises into long-term expanding organoids被引量:1
《Biomaterials Translational》2024年第4期451-453,共3页Zhu A.ZZheng Wei Wang Fu M.Yang Wei Q.Liu Guo S.Han 
supported by the Foundation of National Center for Translational Medicine(Shanghai)SHU Branch(No.SUITM-202409).
Simulating human brain development accurately has the potential to improve our understanding of human brain development and various brain disorders.Although animal models play an indispensable role in the field of dev...
关键词:SPECIFICITY EXPANDING MAINTAIN 
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