supported by the National Natural Science Foundation (NNSF)of China (Nos.82001663);Young Elite Scientists Sponsorship Program by China Association for Science and Technology (No.2020-QNRC1-03);Joint Fund of Beijing University of Traditional Chinese Medicine and USANA.
Inhibition of NLRP3 inflammasome activation produces potent therapeutic effects in a wide array of inflammatory diseases.Bergapten(BeG),a furocoumarin phytohormone present in many herbal medicines and fruits,exibits a...
supported by the Project of Department of Science and Technology of Zhejiang Province, China (No.2021C04021).
In this study, bergapten was synthesized in a yield of 55% from phloroglucinol as starting material, via a novel approach including monomethylation, Hoesch reaction, acetylation, deacetoxylation, Pechmann condensation...
supported by the grants from Natural Science Foundation of Shanghai([2020] 20ZR1431700);Fundamental Research Program Funding of Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine(No.JYZZ102)。
The bacteria-mediated inflammatory conditions adversely affect the osseointegration process of endosseous implants,which can even lead to implant malfunction or failure.Local drug delivery has been designed to exert a...
Major Medical and Health Project of Science and Technology Plan of Zhongshan City,Guangdong Province(2017B1006);Project of Traditional Chinese Medicine Bureau of Guangdong Province(20182168).
[Objectives]To establish a qualitative identification and content determination method for psoralen and bergapten in the roots and leaves of Ficus pandurata,and the multi-indicator scoring method to optimize the ethan...
supported by a project of the National Natural Science Foundation of China(Grant No.81303237);the Training Project of Young Scientists in Jiangxi Province(No.20153BCB23019);China Postdoctoral Science Foundation(2016M590606);the National Natural Science Foundation of Jiangxi Province(20161ACB21020)
Objectives: To investigate the effects of bergapten of Angelicae Dahuricae Radix on the transport of vincristine and its possible mechanism.Methods: The apparent permeability coefficient(Papp) for the transport of vin...
supported by Shenzhen Longhua District Science and Technology Innovation Fund Projects(20160523A1030149)
OBJECTIVE Bergapten(BG),is a furanocoumarin derived from herbal and citrus extracts can act as antioxidant and selective anticancer agents.The current study aimed to investigate whether bergapten would attenuate immun...
This review examines the biological properties of coumarins, widely distributed at the highest levels in the fruit, followed by the roots, stems and leaves, by considering their beneficial effects in the prevention of...
the Project of Researches in Application and Development of Figs in Atushi aided by Atushi Agricultural Bureau in Xinjiang, China
Objective To identify and analyze the volatile constituents in the leaves and fruits of Ficus carica. Methods Gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) were used. Results The major compo...