云南高校图书馆联盟文献共享服务平台- MUSCIMOL

MUSCIMOL: 作品数：15被引量：14H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：刘杰马慧楚向丽王建军高杨更多>>; 相关机构：复旦大学重庆三峡学院云南中医药大学云南大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《中国科技期刊数据库医药》《燕山大学学报》更多>>; 相关基金：国家自然科学基金云南省自然科学基金江苏省自然科学基金国家重点基础研究发展计划更多>>

健康成年小鼠和AD模型小鼠在GABA受体调节后脑电与记忆的不同相关模式被引量：1: 《中山大学学报（自然科学版）（中英文）》2022年第3期11-20,共10页周正李连娥段梦思孙华英易虎付玉; 国家自然科学基金(81760258,81560221,81703497,61972158);云南省自然科学基金(2017FB125,2017FD067)。; 正常衰老和阿尔茨海默病(AD,Alzheimer′s disease)都与大脑萎缩、神经元丢失、神经递质紊乱以及认知退化有关,并且这些变化在AD中更为明显,进展更加快速。因此,有人提出了AD表现出加速衰老的这一假设。AD和正常衰老都涉及兴奋/抑制(E/I...; 关键词：衰老加速阿尔茨海默病(Alzheimer′s disease AD) BICUCULLINE GABA_(A) MUSCIMOL 空间记忆

VTA区GABA A受体调控DA能神经元放电对小鼠抑郁样行为的影响: 《中国科技期刊数据库医药》2021年第8期185-186,共2页张丹旭孙蕊贺凌霄黄锦怡; 探究腹侧被盖区(ventral tegmental area,VTA)GABAA受体的激活对小鼠抑郁样行为的影响。方法:c57/BL-6雄性小鼠VTA区置管给药,分别注射生理盐水、γ羟基丁酸(GABA)、muscimol(GABAA受体激动剂)、bicuculline(GABAA受体拮抗剂),测量小鼠...; 关键词：GABA A受体悬尾试验 MUSCIMOL BICUCULLINE 抑郁样行为

GABA_A Receptor Activity Suppresses the Transition from Interictal to Ictal Epileptiform Discharges in Juvenile Mouse Hippocampus被引量：4: 《Neuroscience Bulletin》2018年第6期1007-1016,共10页Yan-Yan Chang Xin-Wei Gong Hai-Qing Gong Pei-Ji Liang Pu-Ming Zhang Qin-Chi Lu; supported by the Key Basic Research Project of Science and Technology Commission of Shanghai (13DJ1400303);the Shanghai Jiao Tong University Fund for Interdisciplinary Research for Medical Applications (YG2012ZD08);the Seed Fund of Ren Ji Hospital (RJ ZZ13-005); Exploring the transition from inter-ictal to ictal epileptiform discharges(IDs) and how GABAAreceptormediated action affects the onset of IDs will enrich our understanding of epileptogenesis and epilepsy treatment.We ...; 关键词：Epileptiform discharge Gamma-aminobutyric acid BICUCULLINE MUSCIMOL Micro-electrode array Hippocampal slice

Differential Effect of Unilateral Amygdalar GABA<sub>A</sub> Receptor Agonist Injection on Low- and High-Anxiety Rats: 《Journal of Behavioral and Brain Science》2016年第1期9-18,共10页Maria P. Rysakova Irina V. Pavlova; The influence of γ-aminobutyric type-A (GABA_A) receptors agonist (muscimol hydrobromide, 0.1 μg/0.5 μl) injections into the right or left basolateral amygdala (BLA) on the behavior of high-anxiety (HA) a...; 关键词：ANXIETY Basolateral Amygdala GABA_A Receptor Muscimol Hydrobromide Hemispheric Lateralization

Dopamine and GABA Interaction in Basal Ganglia: GABA-A or GABA-B Receptor Stimulation Attenuates L-DOPA-Induced Striatal and Nigral ERK1/2 Signaling in a Rat Model of Parkinson’s Disease: 《Journal of Behavioral and Brain Science》2013年第6期479-488,共10页Sarah Lynch Subbiah P. Sivam; Parkinson’s disease (PD) is characterized by degeneration of nigrostriatal dopamine (DA) neurons. The primary drug used to treat PD symptoms is L-DOPA, but side effects such as dyskinesias limit its use. Previous fin...; 关键词：DOPAMINE ERK1/2 HEMIPARKINSONISM GABA Striatum Substantia Nigra MUSCIMOL BACLOFEN

Muscimol microinjection into cerebellar fastigial nucleus exacerbates stress-induced gastric mucosal damage in rats被引量：3: 《Acta Pharmacologica Sinica》2013年第2期205-213,共9页Jin-zhou ZHU Suduan FEI Jian-fu ZHANG Sheng-ping ZHU Zhang-bo LIU Ting-ting LI XiaoQIAO; Aim： To investigate the effects of microinjection of the GABAA receptor agonist muscimol into cerebellar fastigial nucleus （FN） on stress- induced gastric mucosal damage and the underlying mechanism in rats. Method...; 关键词：CEREBELLUM fastigial nucleus decussation of superior cerebellar peduncle lateral hypothalamic area GABA MUSCIMOL BICUCULLINE gastric mucosa stress-induced gastric mucosal damage apoptosis

Expression of gamma-aminobutyric acid type A receptor α_2 subunit in the dorsal root ganglion of rats with sciatic nerve injury被引量：1: 《Neural Regeneration Research》2012年第32期2492-2499,共8页Yu Lian Yang Wang Ketao Ma Lei Zhao Zhongshuang Zhang Yuanyuan Shang Junqiang Si Li Li; supported by the Youth Science and Technology Innovation Special Foundation of Xinjiang Production and Construction Corps, China, No. 2010JC33; The γ-aminobutyric acid neurotransmitter in the spinal cord dorsal horn plays an important role in pain modulation through primary afferent-mediated presynaptic inhibition. The weakening of γ-aminobutyric acid-media...; 关键词：γ-aminobutyric acid γ-aminobutyric acid type A receptor α2 subunit neuropathic pain dorsal root ganglion whole-cell patch clamp IMMUNOFLUORESCENCE primary afferent depolarization paw withdrawal latency MUSCIMOL

Classical eyeblink conditioning using electrical stimulation of caudal mPFC as conditioned stimulus is dependent on cerebellar interpositus nucleus in guinea pigs被引量：1: 《Acta Pharmacologica Sinica》2012年第6期717-727,共11页Guang-yan WU Juan YA Zheng-li FAN Lang-qian ZHANG Xuan LI Chuang-dong ZHAO Zhen-hua ZHOU Jian-feng SUI; Aim： To determine whether electrical stimulation of caudal medial prefrontal cortex （mPFC） as conditioned stimulus （CS） paired with airpuff unconditioned stimulus （US） was sufficient for establishing eyeblink c...; 关键词：associative learning memory eyeblink conditioning medial prefrontal cortex cerebellar interpositus nucleus MUSCIMOL guinea pig

Involvement of basolateral amygdala GABAA receptors in the effect of dexamethasone on memory in rats: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2011年第11期900-908,共9页Lotfollah KHAJEHPOUR Acieh ALIZADEH-MAKVANDI Mahnaz KESMATI Hooman ESHAGH-HAROONI; supported by the Shahid Chamran University of Ahvaz,Iran; In this study we investigated whether GABAA receptors of the basolateral amygdala(BLA) interact with the effect of dexamethasone on the retrieval stage of memory.Adult male Wistar rats were bilaterally cannulated in t...; 关键词：Basolateral amygdala DEXAMETHASONE MUSCIMOL BICUCULLINE Passive avoidance task

Intracisternal or intrathecal glycine, taurine, or muscimol inhibit bicuculline-induced allodynia and thermal hyperalgesia in mice: 《Acta Pharmacologica Sinica》2010年第8期907-914,共8页II-ok LEE Eui-sung LIM; Aim： To investigate the effects of GABA and glycine on analgesia in the central nervous system. Methods： Glycine, taurine, or muscimol was injected with bicuculline into the cistern magna or the lumbar subarachnoida...; 关键词：ALLODYNIA HYPERALGESIA BICUCULLINE GLYCINE intracisternal intrathecal drug delivery

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