the National Key Research and Development Project of Stem Cell and Transformation Research,No.2019YFA0112100;the National Natural Science Foundation of China(Key Program),No.81930070(both to SF)。
Patients with potential spinal stenosis are susceptible to central cord syndrome induced by blunt trauma.Suitable animal models are helpful for studying the pathogenesis and treatment of such injuries.In this study,we...
supported by the National Research Foundation(NRF)of Korea grant funded by Korean Government(MEST)(No.2011-0030072)
Dominant intermediate Charcot-Marie-Tooth disease type C(DI-CMTC) is a dominantly inherited neuropathy that has been classified primarily based on motor conduction velocity tests but is now known to involve axonal a...
funded by the National Natural Science Foundation of China,No. 30770765
In this study, we investigated the effects of adenovirus-mediated transfection of PC12 cells with glucose transporter 3 after ischemic injury. The results of flow cytometry and TUNEL showed that exogenous glucose tran...
Neural stem cells transplantation plays an important role in repair and cell replacement therapy for nervous system degenerative diseases. However, the self-repair effects are minimal because of a limited absolute num...
Research Fund for the Doctoral Program of Higher Education of China, No. 20060392003
Rat bone marrow mesenchymal stem cells expressing brain-derived neurotrophic factor were successfully obtained using a gene transfection method, then intravenously transplanted into rats with spinal cord injury. At 1,...
the National Natural Science Foundation of China, No. 30672136
Previous studies have confirmed that motor neuron apoptosis in the anterior horn of the lumbosacral spinal cord is positively correlated with p75 neurotrophin receptor (p75NTR) expression in rat models of cauda equi...
BACKGROUND: Neural stem cell (NSC) survival is closely associated with cell apoptosis in ischemic-hypoxic regions following transplantation. Numerous studies have revealed that X-box binding protein 1 (XBP1) is a...
the National Natural Science Foundation of China,No.30570626;the Natural Science Foundation of Beijing,No.7082028
BACKGROUND: The transcription factor Oligl is required for oligodendrocyte maturation and demyelinated lesion repair, and is a key regulator of myelinogenesis following ischemia. OBJECTIVE: To examine the efficacy o...
the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, No. 002006006
BACKGROUND:Several studies have demonstrated that Kallikrein gene transfer provides neuroprotection. Whether the neuroprotective effects of human tissue Kallikrein (HTK) are associated with apoptosis remains unclea...
Key Program of Chongqing Municipal Health Bureau,No. 06-01-020
BACKGROUND: Hypoxia-inducible factor-1 (HIF-1) accumulates under conditions of hypoxia. HIF-1α target genes have pleiotropic effects on neurogenesis, neuroprotection and angiogenesis in the brain. OBJECTIVE: To i...