AMIKACIN

作品数：19被引量：65H指数：4
导出分析报告
相关领域：医药卫生更多>>
相关作者：王明贵张婴元施耀国张菁朱德妹更多>>
相关机构：复旦大学中国医科大学浙江大学医学院附属儿童医院浙江大学更多>>
相关期刊：《Journal of Intensive Medicine》《Chinese Medical Journal》《Chemical Research in Chinese Universities》《Asian Journal of Andrology》更多>>
相关基金：国家自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Nebulized aminoglycosides for ventilator-associated pneumonia:Methodological considerations and lessons from experimental studies
《Journal of Intensive Medicine》2025年第1期12-22,共11页Jean-Jacques Rouby Jing Xia Jayesh Dhanani Gianluigi Li Bassi Antoine Monsel Antoni Torres on behalf of the European Investigators Network for Nebulized Antibiotics in Ventilator-associated Pneumonia(ENAVAP) 
Aminoglycosides are concentration-dependent antibiotics exerting a bactericidal effect when concentrations at the site of infection are equal to or greater than 5 times the minimum inhibitory concentrations(MIC).When ...
关键词：AMINOGLYCOSIDES Ventilator-associated pneumonia Nebulized amikacin Nebulized tobramycin Lung microdialysis Experimental intensive care unit 
Appropriateness of Amikacin Dose Prescription, Monitoring and Safety during Hospitalization as an Impact of Clinical Pharmacologist Intervention, in the Israeli Regional Hospital
《Journal of Biosciences and Medicines》2024年第3期337-354,共18页Renata Shihmanter Olga Lazar Lidia Arcavi 
Background: Use of inappropriate amikacin dose is one of the most important factors in inducing toxicity, prolonged hospitalization as well as in increasing patient’s mortality. Objective: The aims of this study are ...
关键词：AMIKACIN Therapeutic Drug Monitoring APPROPRIATE Clinical Pharmacologist SAFETY Adverse Effects 
Mechanisms and pharmacokinetic/pharmacodynamic profiles underlying the low nephrotoxicity and ototoxicity of etimicin被引量：12
《Acta Pharmacologica Sinica》2020年第6期866-878,共13页Lan Yao Jing-wei Zhang Bin Chen Ming-min Cai Dong Feng Qi-zhi Wang Xin-yu Wang Jian-guo Sun Yi-wen Zheng Guang-ji Wang Fang Zhou 
This work was supported by the National Natural Science Foundation of China(81573496,81773989,81530098,and 81573494);the China"Creation of New Drugs"Key Technology Projects(2015ZX09501001,2017ZX09304021);the National Science and Technology Major Project of China(2019ZX09721001-006-005);the International Science and Technology Cooperation Program of China(2017YFE0109600);the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(No.81421005);the Natural Science Foundation of Jiangsu Province(No.BK20160076);the six talent peaks project in Jiangsu Province(YY-060);and the"Double First-Class"University project(CPU2018GF01).
Etimicin(ETM),a fourth-generation aminoglycosides(AGs),is now widely clinically used in China due to its high efficacy and low toxicity.However,the mechanisms underlying its low nephrotoxicity and ototoxicity remain u...
关键词：AMINOGLYCOSIDE ETIMICIN gentamicin AMIKACIN NEPHROTOXICITY OTOTOXICITY pharmacokinetics mitochondria 
Aerosolized Amikacin as Adjunctive Therapy of Ventilator-associated Pneumonia Caused by Multidrug-resistant Gram-negative Bacteria： A Single-center Randomized Controlled Trial被引量：21
《Chinese Medical Journal》2017年第10期1196-1201,共6页Chang Liu Yu-Ting Zhang Zhi-Yong Peng Qing Zhou Bo Hu Hui Zhou Jian-Guo Li 
Background： Aerosolized amikacin （AA） is a current option for the management of ventilator-associated pneumonia （VAP） caused by multidrug-resistant Gram-negative bacteria （MDR-GNB）, as it is reported that AA co...
关键词：Aerosol Drug Therapy AMIKACIN Gram-negative Bacteria Multidrug Resistance Pnet  monia  Ventilator-associated 
Serum and Blister Fluid Pharmacokinetics of Amikacin in Severe Burn Patients
《International Journal of Clinical Medicine》2015年第11期852-858,共7页Rong Hua Hongliang Xu Xinzhou Rong Ronghua Yang 
Objective: To characterize amikacin pharmacokinetics in serum and in blister fluid of severe burn patients to guide optimal treatment timing. Methods: Patients (N = 32) were divided into four groups based on amikacin ...
关键词：AMIKACIN PHARMACOKINETICS BLISTER FLUID SERUM Severe Burn PATIENTS 
Antimicrobial Susceptibility of Multidrug-Resistant <i>Acinetobacter baumanii</i>in a Teaching Hospital: A Two-Year Observation
《Open Journal of Medical Microbiology》2015年第2期85-89,共5页Cucunawangsih   Veronica Wiwing Nata Pratama Hardjo Lugito 
Multidrug-resistant (MDR) Acinetobacter baumanii (A. baumanii) caused hospital acquired infection, typically in critical-ill patients with medical devices. This is a retrospective descriptive study on epidemiology and...
关键词：MULTIDRUG-RESISTANT ACINETOBACTER baumanii ANTIMICROBIAL Susceptibility AMIKACIN 
Silver nitrate restores susceptibility of clinical multidrug resistant gram-negative and gram-positive bacteria to amikacin in vitro
《Journal of Chinese Pharmaceutical Sciences》2014年第7期500-503,共4页刘存宝 黄唯巍 杨旭 姚宇峰 孙文佳 马雁冰 
Peking Union Medical College(PUMC)Youth Fund and the Fundamental Research Funds for the Central Universities,China(Grant No.333203084)
Silver nitrate could inhibit the clinical multidrug resistant isolates at high concentrations（with minimal inhibitory concentrations（MICs） from 32 μM to 64 μM）. The activities of amikacin in the presence of sub-...
关键词：Silver nitrate AMIKACIN SUSCEPTIBILITY Multidrug resistance Clinical isolates 
Reagent-free determination of amikacin content in amikacin sulfate injections by FTIR derivative spectroscopy in a continuous flow system被引量：1
《Journal of Pharmaceutical Analysis》2014年第2期125-131,共7页José F.Ovalles Máximo Gallignani María R.Brunetto Rebeca A.Rondón Carlos Ayala 
the CDCHTA of the University of Los Andes for providing financial support through several approved projects;the National Fund for Science, Technology and Innovation (FONACIT) of Venezuelan Ministry of Science and Technology for providing financial support, SPE 112–370 and Project G-2005000641
The quantitative estimation of amikacin （AMK） in AMK sulfate injection samples is reported using FTIR-derivative spectrometric method in a continuous flow system. Fourier transform of mid-IR spectra were recorded wi...
关键词：AMIKACIN FlrIR derivative spectro-metry Continuous flow system Pharmaceuticalpreparation INJECTION SULFATE 
(-)-Epigallocatechin-3-gallate protects spiral ganglion neurons against amikacin-induced apoptosis
《Neural Regeneration Research》2011年第27期2112-2117,共6页Qianghe Liu Dinghua Xie Xinming Yang 
Morphology of spiral ganglion neurons （SGNs） in Sprague-Dawley rats before and after amikacin treatment was observed by transmission electron microscopy. Amikacin induced cochlear SGN apoptosis. Immunohistochemical ...
关键词：amikacin apoptosis （-）-epigallocatechin-3-gallate Bcl-2 Bax caspase-3 caspase-6 spiral ganglion neuron neural regeneration 
Alteration of some cellular function in amikacin resistant Pseudomonas aeruginosa transfected macrophages:a time dependent approach被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2011年第6期482-487,共6页Subhankari Prasad Chakraborty Santanu KarMahapatra Sabyasachi Das Somenath Roy 
Supported from a grant by Department of Biotechnology.India(NO:BT/PR10861/NNT/28/131/2008)
Objective:To evaluate the free radical generation and antioxidant enzymes status in murine peritoneal macrophage during in vitro amikacin resistant Pseudomonas aeruginosa(ARPA) treatment with different time interval.M...
关键词：Antioxidant enzyme ARPA Oxidative stress PERITONEAL MACROPHAGE Free radical generation 
全选清除导出
共3页<123>
检索报告 对象比较 聚类工具 使用帮助 返回顶部