supported by the Fifth Key Project of Jiangsu Vocational Education Teaching Reform Research under Grant ZZZ13;in part by the Science and Technology Project of Changzhou City under Grant CE20215032.
Through semi-supervised learning and knowledge inheritance,a novel Takagi-Sugeno-Kang(TSK)fuzzy system framework is proposed for epilepsy data classification in this study.The new method is based on the maximum mean d...
National Natural Science of China(No.81760674);Hainan Graduate Innovative Research Project(No.Hys2020-371)。
Objective:To investigate the therapeutic effects and mechanisms of Feng-Liao-Chang-Wei-Kang combined with 5-fluorouracil administration in mice with colitis-associated colon cancer.Methods:To establish a colitis-assoc...
Supported by National Natural Science Foundation of China (81760674);Foundation of Hainan Provincial Health Commission (21A200444)
[Objectives]To analyze the clinical effect of Feng-Liao-Chang-Wei-Kang Granule combined with mesalazine on chronic colitis.[Methods]120 patients with chronic enteritis admitted to Qionghai Hospital of Traditional Chin...
Supported by China Postdoctoral Science Foundation(No.2020M672745);the Research Project of Traditional Chinese Medicine Bureau of Guangdong Province(No.20201149,Ultrasound-delivery System to Deliver Solasonine to Regulate miR-141-3p and Enhance the Inhibition of Lung Cancer by Gefitinib);the National Natural Science Foundation of China of China(No.81503507:Exploring the Mechanism on Reversal of Gefitinib Resistance in Treating Non-Small Cell Lung Cancer by Fuzhengkangai Decoction base on miRNA-206/449a,81974543:Research on Fuzheng kang’ai Formula Reversing the Drug Resistance to Gefitinib in Non-Small Cell Lung Cancer(NSCLC)via inducing Ferroptosis by Regulating Ferritin and 81803919:the Molecular Mechanism of Fuzheng Kang-ai Decoction Reversing EMT based on Crosstalk between Tumor and Its Microenvironment)
OBJECTIVE:To elucidate the potential molecular mechanism by which Fuzheng Kang’ai decoction(扶正抗癌方,FZKA)inhibits proliferation,migration,and invasion of lung cancer cells.METHODS:Varying FZKA concentrations were ...
Supported by the Special Funds of Science and Technology Development of the Chinese Central Government to Guide Local in 2020(No.21JR1RA066,20JR10FA667);Hospital Fund of the First Hospital of Lanzhou University(No.ldyyyn2007-03)。
Objective:To study the mechanism of Chinese herbal medicine Fuzheng Kang’ai Formula(FZKA)on tumor microenvironment(TME).Methods:CIBERSORTx was used for analysis of TME.Traditional Chinese Medicine Systems Pharmacolog...
supported by the Science and Technology Department of Zhejiang Province,China(Nos.2018C02048 and 2018F10076);the Agricultural and Social Development Department of Hangzhou City,China(2018)。
With the occurrence of aging process,decreased neuron dopamine,disrupted brown adipose tissue(BAT)remodeling and decreased butyrate level all reflect a weak host healthy in certain degree.Nevertheless,the signs of mid...
Traditional Chinese medicine (TCM) formulas have attracted increasing attention worldwide in the past few years for treating complex disease including rheumatoid arthritis. However, their mechanisms are complex and re...
Objective: To study the effects of Kang Ai injection + conventional chemotherapy on tumor markers, apoptotic molecules and immune response in patients with advanced non-small cell lung cancer (NSCLC). Methods: Patient...
Supported by the National Natural Science Foundation of China(No.81273965,81503507);the Natural Science Foundation of Guangdong Province(No.2015A030310245)
Objective: To evaluate the effect of Fuzheng Kang'ai Formula (扶正抗癌方, FZKA) plus gefitinib in patients with advanced non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutations. Methods...
Objective To observe the effect of Fuzheng Kang’ai Recipe(FKR)combined with gefitinib on the proliferation and apoptosis of lung cancer A549 cells,and to study its potential synergistic mechanish with gefitinib.Metho...