Supported by National Natural Science Foundation of China,No.81472861;The Key Project of Zhejiang Province Science and Technology Plan,China,No.2014C03048-1;Hangzhou Municipal Commission of Health and Family Planning Science and Technology Program,No.B20210355.
BACKGROUND Primary seminoma of the prostate(PSP)is a rare type of extragonadal germ cell tumour that is easily misdiagnosed,owing to the lack of specific clinical features.It is therefore necessary for clinicians to w...
Seminomas are most commonly diagnosed in clinical stage I(CSI).After orchiectomy,approximately 15%of patients in this stage have subclinical metastases.Adjuvant radiotherapy(ART)delivered to the retroperitoneum and ip...
supported by the grant from the National Natural Science Foundation of China(No.81771543).
Testicular seminoma is a relatively rare tumor which is mostly detected in male population aged from 15 to 35 yearsold. Although several molecular biomarkers have been identified to be associated with testicular semin...
BACKGROUND Late relapses of early-stage germ cell tumors are rare.Most patients(-85%)with stage I seminoma are cured by radical orchiectomy.The detection of late relapse is challenging given the relative rarity of thi...
MicroRNAs(miRNAs)are small noncoding RNAs involved in the regulation of mRNA transcription and translation,and possess all desirable features of an ideal tumor marker.Of almost 31 different miRNA clusters identified i...
Spermatogenesis is regulated by a complex network of posttranslation modifications.Sumoylation(a modification by small ubiquiti like modifiers,or SUMO proteins)was identified as an importa nt cellular event in d iff e...
The authors would like to thank all patients involved in this study.This work was funded by the National Natural Science Foundation of China(No.81572531).The funding source provided financial support for the study and did not have any other involvement in this study.
The aims of this study were to determine the prog no stic value of primary tumor surgery and identify optimal can didates for such surgery among patients with semi noma and dista nt metastasis at diag no sis.We ide nt...
Objective: To study the clinics and therapeutics of testicular cancer not descended in Senegal. Patients and Methods: This is a retrospective study over a period of 15 years between January 1997 and January 2012. It f...
Financial support for this study was provided by the American Center for Reproductive Medicine,Cleveland Clinic,OH,USA;Tania R Dias was supported by the Portuguese Foundation for Science and Technology(FCT,SFRH/BD/109284/2015);Fulbright Program(E0585639).
Testicular cancer seminoma is one of the most common types of cancer among men of reproductive age.Patients with this condition usually present reduced semen quality,even before initiating cancer therapy.However,the u...
Seminoma is a germ cell tumour which primarily affects the testes. Seminomas are treated by orchidectomy with usually excellent outcomes. We report the occurrence of a classical seminoma in a 92-year-old man,who is cu...