云南高校图书馆联盟文献共享服务平台- CLEARANCE

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Systematic review of amyloid-beta clearance proteins from the brain to the periphery:implications for Alzheimer's disease diagnosis and therapeutic targets: 《Neural Regeneration Research》2025年第12期3574-3590,共17页Letian Huang Mingyue Liu Ze Li Bing Li Jiahe Wang Ke Zhang; supported by the National Natural Science Foundation of China,No.81571046(to KZ);Key Project of Educational Department of Liaoning Province,No.LJKZ0755(to KZ);Project of Department of Science&Technology of Liaoning Province,No.2023JH2/20200116(to KZ);Shenyang Young and Middleaged Innovative Talents Support Program,No.RC210240(to KZ);the 345 Talent Project of Shengjing Hospital of China Medical University(to LH)。; Amyloid-beta clearance plays a key role in the pathogenesis of Alzheimer's disease.H oweve r,the variation in functional proteins involved in amyloid-beta clearance and their correlation with amyloid-beta levels remai...; 关键词：Alzheimer’s disease amyloid-β blood‒brain barrier cerebrospinal fluid diagnostic biomarker meta-analysis mild cognitive impairment peripheral blood systematic review therapeutic targets

Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance: 《Neural Regeneration Research》2025年第3期695-714,共20页Beibei Wu Yuqing Liu Hongli Li Lemei Zhu Lingfeng Zeng Zhen Zhang Weijun Peng; financially supported by the Science and Technology Innovation Program of Hunan Province,No.2022RC1220(to WP);China Postdoctoral Science Foundation,No.2022M711733(to ZZ);the National Natural Science Foundation of China,No.82160920(to ZZ);Hebei Postdoctoral Scientific Research Project,No.B2022003040(to ZZ);Hunan Flagship Department of Integrated Traditional Chinese and Western Medicine(to WP)。; Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofibrillary tangles.Although amyloid plaques are the primary ch...; 关键词：ABCA1 Alzheimer's disease AMYLOID-BETA apolipoprotein E cholesterol metabolism LIVER liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid

Apoptotic clearance by stem cells: molecular mechanisms for recognition and phagocytosis of dead cells: 《Signal Transduction and Targeted Therapy》2025年第1期18-20,共3页Feng Liu Xiaobo Zhou Ibrahim Akin; supported by DZHK(German Center for Cardiovascular Research),the BMBF(German Ministry of Education and Research)(No.81Z0500204);the Hector foundation(M2401)and Sichuan Science and Technology Program(2022YFS0610).; In a recent article published in Nature,Stewart and co-workers provide transformative insights into the mechanisms by which hair follicle stem cells(HFSCs)regulate apoptotic cell clearance to maintain tissue fitness.T...; 关键词：MECHANISMS MAINTAIN PRECISE

Continuous Contact Model of Metamorphic Groove Pin Pair with Clearance: 《Applied Mathematics》2025年第1期15-41,共27页Jiangxue Hu Liang He Yaping Wang Lihua Yang Ganwei Cai; Metamorphic mechanism has the advantages of variable topology and variable degrees of freedom, which can realize the requirements of multi-conditions and multi-tasks, and has a good application prospect. The configura...; 关键词：Metamorphic Mechanism Metamorphic Pair with Clearance ContinuousContact Model Metamorphic Groove Pin Pair

Analysis of air curtain system flow field and droplet drift characteristics of high clearance sprayer based on CFD: 《International Journal of Agricultural and Biological Engineering》2024年第6期38-45,共8页Yangyang Song; High clearance sprayers are widely used in field operations because of their high ground clearance and good passing performance,which can solve the problem of spraying high-stalk crops in the middle and late stages.In...; 关键词：air curtain system CFD numerical simulation droplet drift rate multiple working conditions

Ship Propeller Rotation Threshold to Prevent Erosion and Sedimentation in Coastal Waters: 《哈尔滨工程大学学报(英文版)》2024年第4期798-811,共14页Abdul Kadir I.Istadi Agus Subagio I.Iskendar W.Waluyo Abdul Muis Dewi Kartikasari Siti Sadiah A.B Widagdo M.P Helios Mochammad Nasir N.Nurhadi; The rotation of a ship’s propeller can accelerate the water flow around it,which puts pressure on seabed particles.Continuous pressure on the seabed can significantly trigger erosion and sedimentation of coastal wate...; 关键词：Landing craft tank Water flow velocity Seabed erosion Under keel clearance

Numerical simulation of the electromagnetic torques of PMSM with two-way magneto-mechanical coupling and nonuniform spline clearance in electric submersible pumping wells: 《Petroleum Science》2024年第6期4417-4426,共10页Xin-Fu Liu Chun-Hua Liu Ying Zheng Ji-Fei Yu Wei Zhou Meng-Xiao Wang Peng Liu Yi-Fei Zhou; financially supported by National Natural Science Foundation of China(Grant Nos.52074161 and 52005281);Taishan Scholar Project of Shandong Province(Grant No.tsqn202211177);Shandong Provincial Plan for Introduction and Cultivation of Young Pioneers in Colleges and Universities(Grant No.2021-Qing Chuang-30613019);Natural Science Foundation of Shandong Province(Grant Nos.ZR2022ME173 and ZR2023QE011);Projects of CNOOC Research Institute Ltd.(Grant Nos.CCL2023RCPS0237RSN and CCL2023RCPS0319RSN)。; Clearance-fit(side-fit)spline joints are a key component in a permanent magnet synchronous motor(PMSM)in electric submersible pumping wells.The nonuniform spline clearance affects the output performance of a PMSM.A co...; 关键词：Permanent magnet synchronous motor Two-way coupling Magneto-mechanical coupling Nonuniform splineclearance Electromagnetic torque

Efferocytosis:A new therapeutic target for stroke: 《Chinese Medical Journal》2024年第23期2843-2850,共8页Li Gao Anatol Manaenko Feng Zeng Jingchen Li Lele Liu Ruichuan Xie Xiaohua Zhang John HZhang Qiyong Mei Jiping Tang Qin Hu; supported by grants from the National Natural Science Foundation of China(Nos.82071283,82371332,and 81801298);the Natural Science Foundation of Shanghai(No.22ZR1437700);the Research Program of Science and Technology Commission of Shanghai Municipality(No.201409005300);Shanghai Engineering Research Center of Peri-operative Organ Support and Function Preservation(No.20DZ2254200).; Efferocytosis refers to the process that phagocytes recognize and remove the apoptotic cells,which is essential for maintaining tissue homeostasis both in physiological and pathological conditions.Numerous studies hav...; 关键词：STROKE EFFEROCYTOSIS Inflammation resolution Apoptotic cell clearance

A New Approach to Suppress Tip Leakage Flow Utilizing Induced Shock Wave in Tip Region of a TransonicCompressor Rotor: 《Journal of Thermal Science》2024年第6期2059-2074,共16页CUI Weiwei YAO Fei LI Zongming WANG Xiaonan CHANG Guozhang WANG Cuiping; sponsored by the General Program of National Natural Science Foundation of China (Grant No.52076124);the National Science and Technology Major Project (Grant No.J2019-Ⅱ-0014-0035); Tip leakage flow affects the flow stability of high-loading compressors significantly.Therefore,a novel approach via induced shock wave near suction-side edge of blade tip was proposed to suppress the strength and inf...; 关键词：circumferentially diverging clearance induced shock wave leakage flow low-velocity region st marginenhancement

VTOL site location considering obstacle clearance during approach and departure: 《Communications in Transportation Research》2024年第1期24-35,共12页Chenhao Guo Jianxiong Nie Xu Hang Yanjun Wang Yanyan Chen Daniel Delahaye; National Natural Science Foundation of China(Grant Nos.U2033203 and 52272333);Fundamental Research Funds for Central Universities of Nanjing University of Aeronautics and Astronautics(Grant No.3082022NS2022067).; Urban air mobility(UAM)extends urban transportation to low-altitude airspace using electric vertical take-off and landing(eVTOL)vehicle to reduce traffic congestion.The vertical take-off and landing(VTOL)site connecti...; 关键词：Urban air mobility(UAM) Vertical take-off and landing(VTOL)site location Advanced air mobility(AAM) Hub location problem Urban transportation

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