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Estrogen receptors in gastric cancer:Advances and perspectives被引量：17: 《World Journal of Gastroenterology》2016年第8期2475-2482,共8页Muhammad Saif Ur Rahman Jiang Cao; Supported by The National Natural Science Foundation of China;No.30271450;No.30471955;No.30672365 and No.81172516; Worldwide, gastric cancer is one of the most common malignancies with high mortality. Various aspects of thedevelopment and progression of gastric cancer continue to be extensively investigated in order to further our...; 关键词：Gastric cancer ESTROGEN receptor ISOFORM CARCINOGENESIS Mechanism GENOMIC PATHWAY NONGENOMIC PATHWAY

Targeting truncated RXRα for cancer therapy被引量：3: 《Acta Biochimica et Biophysica Sinica》2016年第1期49-59,共11页Xiaokun Zhang Hu Zhou Ying Su; Retinoid X receptor-alpha （RXRα）, a unique member of the nuclear receptor superfamily, is a well- established drug target, representing one of the most important targets for pharmacologic interven- tions and therap...; 关键词：tRXRα RXRα modulators nongenomic action INFLAMMATION PI3K

Regulation of the nongenomic actions of retinoid X receptor-a by targeting the coregulator-binding sites: 《Acta Pharmacologica Sinica》2015年第1期102-112,共11页Xiao-kun ZHANG Ying SU Liqun CHEN Fan CHEN Jie LIU Hu ZHOU; Retinoid X receptor-a （RXRa）, a unique member of the nuclear receptor superfamily, represents an intriguing and unusual target for pharmacologic interventions and therapeutic applications in cancer, metabolic disord...; 关键词：RXRa rexinoid RXRa MODULATOR NONGENOMIC action COREGULATOR site apoptosis inflammation PI3K NSAID

The mineralocorticoid receptor-p38MAPK-NFKB or ERK-Spl signal pathways mediate aldosterone- stimulated inflammatory and profibrotic responses in rat vascular smooth muscle cells被引量：3: 《Acta Pharmacologica Sinica》2012年第7期873-878,共6页Chuan-jiang ZHU Qing-qing WANG Jun-lan ZHOU Han-zhi LIU Fang HUA Hong-zheng YANG Zhuo-wei HU; This work was supported by National Natural Science Foundation of China （No 30472025）.; Aim： To explore the signalling pathways involved in aldosterone-induced inflammation and fibrosis in rat vascular smooth muscle cells （VSMCs）. Methods： Using Western blotting and real-time RT-PCR, we investigated ...; 关键词：ALDOSTERONE inflammation fibrosis signal transduction vascular smooth muscle cells mineralocorticoid receptor P38MAPK NF-κB ERK1/2 SPL nongenomic effect

The Nongenomic Effects of Progesterone in Repressing iNOS Activation through P38MAPK Pathways in Gonococci-Infected Polymorphonuclear Leukocytes and the Clinical Significance被引量：3: 《Journal of Huazhong University of Science and Technology(Medical Sciences)》2010年第1期119-125,共7页陈嵘祎涂亚庭林加西佘惟槟李娟吴志洪许莉陈宏翔; supported by the Young Scientists Fund Program of National Natural Science Fund Program from National Natural Sciences Foundation of China(No.30371293);Medical Research Foundation of Guangdong Province of China(No.B2009193); Progesterone has nongenomic effects on inducible nitric oxide synthase(iNOS),which is mediated by mitogen activated protein kinase(MAPK)pathways.This effect is supposed to have some potential association with asymptom...; 关键词：asymptomatic infection gonococcus inducible nitric oxide synthase nongenomic effects PROGESTERONE

Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages: 《第二军医大学学报》2006年第3期243-243,共1页

Rapid nongenomic inhibitory effects of glucocorticoids on phagocytosis and superoxide anion production by macrophages被引量：14: 《第二军医大学学报》2005年第10期1106-1106,共1页Long F Wang YX Liu L Zhou J Cui RY Jiang CL; 关键词：肾上腺皮质激素抑制作用噬菌作用过氧化物巨噬细胞

Corticosterone activates Erk1/2 mitogen-activated protein kinase in primary hippocampal cells through rapid nongenomic mechanism被引量：1: 《Progress in Natural Science:Materials International》2005年第4期325-330,共6页QIAiqun QIUJian XIAOLin CHENYizhang; SupportedbyNationalNaturalScienceFoundationofChina (GrantNos.3 93 3 0 10 0 ;3 9840 0 19)andtheMajorStateBasicResearchDevelopmentProgramofChina (G19990 5 40 0 3 ); Nongenomic effects of glucocorticoids (GC) in various cell types have beenwell documented, but it still remains unknown whether the mechanism also works in hippocampus whichis a crucial target of glucocorticoids in ne...; 关键词：GLUCOCORTICOID MAPK rapid effects nongenomic mechanism

Delayed response of rapid—nongenomic action of glucocortocoid receptor on neural cells: 《中国药理通讯》2002年第4期20-21,共2页陈家张 Ai－qunQi 等; 关键词：神经细胞延迟反应糖皮质激素受体

Signal transduction pathway of glucocorticoid's rapid action in PC12 cells被引量：2: 《Chinese Science Bulletin》1999年第20期1837-1843,共7页Jian Qiu Shujie Lou Yizhang Chen; Traditionally, steroid hormone action has been described as the modulation of nuclear transcription, thus triggering genomic events that are responsible for physiological effects. Despite early observation of rapid st...; 关键词：PC12 cells GLUCOCORTICOID NONGENOMIC SIGNAL transduction.

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