CILIARY

作品数：51被引量：103H指数：6
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相关领域：医药卫生更多>>
相关作者：姚克尹金福吴仁毅张静王洪田更多>>
相关机构：浙江大学医学院附属第二医院中国人民解放军总医院首都医科大学上海交通大学更多>>
相关期刊：《Journal of Diabetes Mellitus》《Advances in Entomology》《Pediatric Investigation》《Open Journal of Epidemiology》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Expression and Clinical Significance of Various Cytokines in Otitis Media
《International Journal of Otolaryngology and Head & Neck Surgery》2024年第1期29-40,共12页Qingchen He Yongbo Zhu Bi Qiang 
The expression and clinical significance of relevant cytokines in otitis media (OM) are discussed, and the alterations to the pathological state of the otitis media mucosa are further understood through the study of c...
关键词：Otitis Media Middle Ear Mucosa CYTOKINES Eustachian Tube Function Ciliary Transport Function 
Ocular manifestations of central insulin resistance被引量：2
《Neural Regeneration Research》2023年第5期1139-1146,共8页Muneeb A.Faiq Trina Sengupta Madhu Nath Thirumurthy Velpandian Daman Saluja Rima Dada Tanuj Dada Kevin C.Chan 
supported by a grant from All India Institute of Medical Sciences,New Delhi (to RD and TD);Indian Council of Medical Research,Senior Research Fellowship Grant (3/1/2(24)/oph-2009-NCD-II,to MAF);Feldstein Medical Foundation Research Grant (to KCC);unrestricted fund from Research to Prevent Blindness to NYU Langone Health Department of Ophthalmology (to KCC)。
Central insulin resistance, the diminished cellular sensitivity to insulin in the brain, has been implicated in diabetes mellitus, Alzheimer’s disease and other neurological disorders. However, whether and how centra...
关键词：brain ciliary bodies gene expression inflammation insulin receptor insulin resistance intraocular pressure NEURODEGENERATION optic nerve RETINA retinal ganglion cells trabecular meshwork 
Ccdc57 is required for straightening the body axis by regulating ciliary motility in the brain ventricle of zebrafish被引量：3
《Journal of Genetics and Genomics》2023年第4期253-263,共11页Lu Li Juan Li Yuan Ou Jiaxin Wu Huilin Li Xin Wang Liying Tang Xiangyan Dai Conghui Yang Zehong Wei Zhan Yin Yuqin Shu 
supported by the National Key Research and Development Program,China(2018YFD0900406);the National Natural Science Foundation,China(31802291);the Natural Science Foundation of Hunan Province(2021JJ40342)。
Recently,cilia defects have been proposed to contribute to scoliosis.Here,we demonstrate that coiled-coil domain-containing 57(Ccdc57)plays an essential role in straightening the body axis of zebrafish by regulating c...
关键词：Scoliosis CSF ccdc57 CILIA EPINEPHRINE UROTENSIN 
The actin-bundling protein Fascin-1 modulates ciliary signalling
《Journal of Molecular Cell Biology》2023年第4期1-16,共16页Lena Brücker Stefanie Kornelia Becker Vanessa Maissl Gregory Harms Maddy Parsons Helen Louise May-Simera 
supported by grants from Johannes Gutenberg University Mainz,Alexander von Humboldt Foundation(Sofja Kovalevskaja Award),Hanns Seidel Foundation,and Sibylle Kalkhof-Rose Foundation.This project was further funded by Deutsche Forschungsgemeinschaft(DFG,German Research Foundation,GRK2526/1-Projectnr.407023052).
Primary cilia are microtubule-based cell organelles important for cellular communication. Since they are involved in the regulation of numerous signalling pathways, defects in cilia development or function are associa...
关键词：CILIA actin Wnt SIGNALLING CILIOPATHY Bardet–Biedl syndrome FILOPODIA 
Human IFT-A complex structures provide molecular insights into ciliary transport
《Cell Research》2023年第4期288-298,共11页Meiqin Jiang Vivek Reddy Palicharla Darcie Miller Sun-Hee Hwang Hanwen Zhu Patricia Hixson Saikat Mukhopadhyay Ji Sun 
Intraflagellar transport(IFT)complexes,IFT-A and IFT-B,form bidirectional trains that move along the axonemal microtubules and are essential for assembling and maintaining cilia.Mutations in IFT subunits lead to numer...
关键词：COMPLEXES INSIGHT RATIONAL 
Impact of smoking on nasal mucociliary clearance time in Kano metropolis,Nigeria
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2023年第1期53-58,共6页Ahmad Mahmud Abubakar D.Salisu Emmanuel S.Kolo Muhammad G.Hasheem Nafisatu Bello-Muhammad Ahmad R.Tukur Yasir J.Nuhu Rabiu I.Jalo 
Background:Mucociliary clearance is an important defense mechanism in human upper and lower respiratory airways.Impairment of this process by certain conditions such as cigarette smoking can predispose to chronic infe...
关键词：ciliary dyskinesia mucociliary clearance saccharin test SMOKING 
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling被引量：1
《International Journal of Oral Science》2023年第1期148-158,共11页Gongsheng Yuan Shuting Yang Shuying Yang 
supported by National Institutes of Health(NIH)grants AG048388 and AR066101 to Dr.Shuying Yang;supported by U.S.Department of Defense(DOD)grants PR201467 and RA210159 to Dr.Shuying Yang。
Tumor-associated macrophages(TAMs)play crucial roles in tumor progression and immune responses.However,mechanisms of driving TAMs to antitumor function remain unknown.Here,transcriptome profiling analysis of human ora...
关键词：INVASION driving RGS 
Doublets of the unicellular organism Euplotes vannus(Alveolata,Ciliophora,Euplotida):the morphogenetic patterns of the ciliary and nuclear apparatuses associated with cell division被引量：2
《Marine Life Science & Technology》2022年第4期527-535,共9页Jinyu Fu Yong Chi Xiaoteng Lu Feng Gao Saleh A.Al-Farraj Giulio Petroni Jiamei Jiang 
supported by the National Natural Science Foundation of China(32030015,31922013 and 31961123002);the Natural Science Foundation of Shandong Province(ZR2020JQ13);the Fundamental Research Funds for the Central Universities(202141004);the Researchers Supporting Project(RSP-2022R7)of the King Saud University,Saudi Arabia.
Ciliated protists are one of the most diverse and highly differentiated group among unicellular organisms.Doublets occur in ciliates when two cells fuse into a single individual.Doublets contain two major cellular com...
关键词：Binary fission CILIATURE Doublet Euplotids Morphogenesis 
Cilia regeneration requires an RNA splicing factor from the ciliary base被引量：1
《Cell Regeneration》2022年第1期303-314,共12页Kaiming Xu Guangshuo Ou 
This work was supported by the National Natural Science Foundation of China(grants 31991190,31730052,31525015,31861143042,31561130153,31671444,31871352);the National Key R&D Program of China(2017YFA0503501,2019YFA0508401,and 2017YFA0102900)。
Cilia are microtubule-based organelles projected from most eukaryotic cell surfaces performing cell motility and signaling.Several previously recognized non-ciliary proteins play crucial roles in cilium formation and ...
关键词：PRP-8/PRPF8 RNA splicing factor CILIOGENESIS Cilium regeneration 
Correction: Cilia regeneration requires an RNA splicing factor from the ciliary base
《Cell Regeneration》2022年第1期426-426,共1页Kaiming Xu Guangshuo Ou 
Following publication of the original article(Xu and Ou 2022),it is reported that the supplement figure S1-S5 were missing from the article.Additional file 1:Fig.S1 contains only figure legends but no figures.
关键词：BASE FIGURE FIGURES 
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