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作品数：92被引量：261H指数：8
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  • 期刊=Chinese Journal of Integrative Medicinex
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Clean-DM1, a Korean Polyherbal Formula, Improves High Fat Diet-Induced Diabetic Symptoms in Mice by Regulating IRS/PI3K/AKT and AMPK Expressionsin Pancreas and Liver Tissues
《Chinese Journal of Integrative Medicine》2024年第2期125-134,共10页Piao Wang Yi Liu Seok Yong Kang Chenzi Lyu Xiang Han Tianjun Ho Kyung Jae Lee Xianglong Meng Yong-Ki Park Hyo Won Jung 
Supported by Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI),the Ministry of Health&Welfare,Republic of Korea (No. HF20C0121);Shanxi Key Laboratory of Tradition Herbal Medicines Processing (No. 20210901);the Innovation Team of Shanxi University of Chinese Medicine (No. 2022TD1014)
Objective:To investigate the effects of Clean-DM1(C-DM1),a polyherbal formulation of Radix Scrophulariae,Radix Astragali,Rhizoma Atractylodis,and Radix Salviae Miltiorrhizae,on high-fat diet(HFD)-induced diabetes mice...
关键词：high-fat diet type 2 diabetes mellitus herbal formulation insulin receptor substrate/phosphatidylinositol 3 kinase/protein kinase B adenosine 5'-monophosphate-activated protein kinase network pharmacology high performance liquid chromatography-mass spectrometry analysis 
Emodin Ameliorates High Glucose-Induced Podocyte Apoptosis via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway被引量：3
《Chinese Journal of Integrative Medicine》2023年第9期801-808,共8页LIU Hong CHEN Wei-dong HU Yang-lin YANG Wen-qiang HU Tao-tao WANG Huan-lan ZHANG Yan-min 
Supported by the Chinese Medicine Research Project of Hubei Provincial Health Commission(No.ZY2019Q024);Scientific Research Project of Wuhan Municipal Health Commission(No.WX20B11);Scientific Research Project of Wuhan Municipal Health Commission(No.WZ20C01)。
Objective To investigate the effect of emodin on high glucose(HG)-induced podocyte apoptosis and whether the potential anti-apoptotic mechanism of emodin is related to induction of adenosine-monophosphate-activated pr...
关键词：EMODIN diabetic nephropathy AUTOPHAGY podocyte apoptosis adenosine-monophosphate-activated protein kinase/mammalian target of rapamycin signaling pathways 
Ginsenoside Rb1 Ameliorates Autophagy of Hypoxia Cardiomyocytes from Neonatal Rats via AMP-Activated Protein Kinase Pathway被引量：5
《Chinese Journal of Integrative Medicine》2019年第7期521-528,共8页DAI Sheng-nan HOU Ai-jie ZHAO Shu-mei CHEN Xiao-ming HUANG Hua-ting CHEN Bo-han KONG Hong-liang 
Supported by Shenyang Innovation Foundation of Science and Technology–the Application Projects of Basic Research(No.F15-199-1-06);Liaoning Province Science and Technique Foundation of China(No.2015020282)
Objective: To investigate whether ginsenoside-Rb1(Gs-Rb1) improves the CoCl2-induced autophagy of cardiomyocytes via upregulation of adenosine 5’-monophosphate-activated protein kinase(AMPK) pathway. Methods: Ventric...
关键词：CARDIOMYOCYTES ginsenosides-Rb1 HYPOXIA ADENOSINE 5'-monophosphate-activated protein KINASE autophagic flux 
Effects of Mitochondrial Dysfunction via AMPK/PGC-1α Signal Pathway on Pathogenic Mechanism of Diabetic Peripheral Neuropathy and the Protective Effects of Chinese Medicine被引量：25
《Chinese Journal of Integrative Medicine》2019年第5期386-394,共9页ZHANG Qian LIANG Xiao-chun 
Supported by the National Natural Science Foundation of China(No.81473639);the Fundamental Research Funds for the Central Universities(No.3332018037)
Diabetic peripheral neuropathy(DPN) is a progressive neurodegenerative disease of peripheral nervous system with high energy requirement. The adenosine monophosphate-activated protein kinase(AMPK)/peroxisome prolifera...
关键词：monophosphate-activated protein kinase PEROXISOME proliferator-activated receptor-γ COACTIVATOR 1α SIRTUINS diabetic peripheral NEUROPATHY Chinese medicine 
Dan-gua Fang (丹瓜方) Improves Glycolipid Metabolic Disorders by Promoting Hepatic Adenosine 5'-monophosphate Activated Protein Kinase Expression in Diabetic Goto-kakizaki Rats被引量：12
《Chinese Journal of Integrative Medicine》2015年第3期188-195,共8页蓝元隆 黄苏萍 衡先培 陈玲 李鹏辉 吴静 杨柳清 潘旭东 林彤 程心玲 林青 陈斯歆 
Supported by the National Natural Science Foundation of China(No.81173179);the Natural Science Foundation of Fujian Province(No.2011J01198);the Fujian Medical Innovation Project(No.2009-CX-19);the Research Foundation of Fujian Health Department(No.Zlcnfm02);the Fujian Provincial Department of Education Category A Projects(No.JA09131);the Fujian Health Department of Traditional Chinese Medicine Research(No.WZY0920);the CHEN Ke-ji Integrative Medicine Development Fund(No.CKJ2008047,CKJ2009004);the Integrative Medicine of Fujian Key Laboratory of Age-related Diseases Funded Projects(No.2008J1004-10)
Objective：To investigate the effect of Dan-gua Fang（丹瓜方） on adenosine 5’-monophosphate（AMP） activated protein kinase（AMPK） α expression in liver and subsequent improvement of glucose and lipid metabolism.M...
关键词：Dan-gua Fang Goto-Kakizaki rat adenosine 5’-monophosphate activated protein kinase type 2 diabetes mellitus liver glucose and lipid metabolism 
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