MONOPHOSPHATE

作品数：92被引量：261H指数：8
导出分析报告
相关领域：医药卫生更多>>
相关作者：肖明芳应汉杰杨晓亮吕浩何明芳更多>>
相关机构：南京工业大学南京大学福建中医药大学中国人民解放军第一军医大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金福建省自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 学科=医药卫生—临床医学x
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood–brain barrier
《Neural Regeneration Research》2026年第1期377-391,共15页Yinying Wang Rongsha Chen Guolin Shi Xinwei Huang Ke Li Ruohua Wang Xia Cao Zhongshan Yang Ninghui Zhao Jinyuan Yan 
supported by the National Natural Science Foundation of China,Nos. 32260196 (to JY), 81860646 (to ZY) and 31860274 (to JY);a grant from Yunnan Department of Science and Technology,Nos. 202101AT070251 (to JY), 202201AS070084 (to ZY), 202301AY070001-239 (to JY), 202101AZ070001-012, and 2019FI016 (to ZY)。
Studies have shown that chitosan protects against neurodegenerative diseases. However, the precise mechanism remains poorly understood. In this study, we administered chitosan intragastrically to an MPTP-induced mouse...
关键词：ACETATE adenosine 5′-monophosphate-activated protein kinase blood–brain barrier CHITOSAN dopamine neurons INFLAMMATION intestinal barrier Parkinson's disease peroxisome proliferator-activated receptor delta short-chain fatty acids 
Akkermansia muciniphila-derived acetate activates the hepatic AMPK/SIRT1/PGC-1a axis to alleviate ferroptosis in metabolic-associated fatty liver disease
《Acta Pharmaceutica Sinica B》2025年第1期151-167,共17页Aoxiang Zhuge Shengjie Li Shengyi Han Yin Yuan Jian Shen Wenrui Wu Kaicen Wang Jiafeng Xia Qiangqiang Wang Yifeng Gu Enguo Chen Lanjuan Li 
supported by the National Natural Science Foundation of China(81790631,81874142,and 82073041);the National Key Research and Development Program of China(2018YFC2000500,2021YFA1301104,and 2021YFC2301804);the CAMS Innovation Fund for Medical Sciences(2019-I2M-5-045,China);the Research Project of Jinan Microecological Biomedicine Shandong Laboratory(JNL-2022001A,China);the China Postdoctoral Science Foundation(2023M743125).
Emerging evidences have indicated the role of ferroptosis in the progression of metabolicassociated fatty liver disease(MAFLD);thus,inhibiting ferroptosis is a promising strategy for the development of MAFLD therapeut...
关键词：Metabolic-associated fatty liver disease Ferroptosis Lipid peroxidation Akkermansia muciniphila ACETATE Adenosine 50-monophosphate 
Fanlian Huazhuo Formula:A promising herbal preparation for metabolic liver disease被引量：1
《World Journal of Gastroenterology》2024年第46期4964-4968,共5页Bhupesh Singla 
Supported by the National Institutes of Health Grants,No.K99HL146954 and No.R00HL146954;the College of Pharmacy Seed Research Grant Program of the University of Tennessee Health Science Center.
The prevalence of metabolic dysfunction-associated steatotic liver disease(MASLD)has increased significantly in recent decades and is projected to increase further due to the rising obesity rates.MASLD patients are at...
关键词：Metabolic dysfunction-associated steatotic liver disease Fanlian Huazhuo Formula De novo lipogenesis Cell death Adenosine-5’-monophosphate-activated protein kinase alpha Acetyl-CoA carboxylase 
Suppression of hepatic steatosis in non-alcoholic steatohepatitis model by modified Xiaoyao San formula:Evidence,mechanisms and perspective
《World Journal of Hepatology》2024年第10期1208-1212,共5页Nabil Eid Payal Bhatnagar Li-Li Chan Marina Garcia-Macia 
In this letter,we comment on a recent publication by Mei et al,in the World Journal of Hepatology,investigating the hepatoprotective effects of the modified Xiaoyao San(MXS)formula in a male rat model of non-alcoholic...
关键词：STEATOSIS Liver Xiaoyao San Inflammation ANDROGEN Adenosine 5’-monophosphate-activated protein kinase Phosphatase and tensin homolog Autophagy Lipophagy Alpha smooth muscle actin 
Suppressing high mobility group box-1 release alleviates morphine tolerance via the adenosine5'-monophosphate-activated protein kinase/heme oxygenase-1 pathway被引量：1
《Neural Regeneration Research》2023年第9期2067-2074,共8页Tong-Tong Lin Chun-Yi Jiang Lei Sheng Li Wan Wen Fan Jin-Can Li Xiao-Di Sun Chen-Jie Xu Liang Hu Xue-Feng Wu Yuan Han Wen-Tao Liu Yin-Bing Pan 
supported by the National Natural Science Foundation of China;Nos.81971047 (to WTL) and 82073910 (to XFW);the Natural Science Foundation of Jiangsu Province,No.BK20191253 (to XFW);Key R&D Program (Social Development) Project of Jiangsu Province,No.BE2019 732 (to WTL);Jiangsu Province Hospital (the First Affiliated Hospital of Nanjing Medical University) Clinical Capacity Enhancement Project,No.JSPH-511B2018-8 (to YBP)。
Opioids,such as morphine,are the most potent drugs used to treat pain.Long-term use results in high tolerance to morphine.High mobility group box-1(HMGB1) has been shown to participate in neuropathic or inflammatory p...
关键词：adenosine 5’-monophosphate-activated protein kinase heme oxygenase-1 high mobility group box-1 INTERLEUKIN-1Β MICROGLIA morphine tolerance NEUROINFLAMMATION neuron nuclear factor-κB p65 Toll-like receptor 4 
Peptide nanotube loaded with a STING agonist,c-di-GMP,enhance cancer immunotherapy against melanoma被引量：1
《Nano Research》2023年第4期5206-5215,共10页Ziyuan Zhang Juan Liu Min Xiao Quanfeng Zhang Zhonghua Liu Meiyan Liu Peng Zhang Youlin Zeng 
supported by the National Natural Science Foundation of China(Nos.21877036 and 32201044);the Key Project of Developmental Biology and Breeding from Hunan Province(No.2022XKQ0205);the Hunan Natural Science Foundation(No.2021JJ40335);the Science and Technology Planning Project of Hunan Province(No.2018TP1017).
The activation of the stimulating factor of the interferon gene(STING)pathway can enhance the immune response within the tumor.Cyclic diguanylate monophosphate(c-di-GMP)is a negatively charged,hydrophilic STING agonis...
关键词：cyclic diguanylate monophosphate stimulating factor of the interferon gene(STING) peptide nanotubes in situ immunity tumor immunotherapy 
Molecular Similarity within Carcinogen and Guanine Cyclic Nucleotide Structures
《Journal of Biosciences and Medicines》2022年第5期86-94,共9页Wynford Robert Williams 
Tumor promoters, apoptosis and autophagy modulators, chemotherapy drugs, and endogenous steroids demonstrate molecular similarity relative to cyclic nucleotide structure. This study explores relative molecular similar...
关键词：ANESTHETICS Cancer CARCINOGENS Guanosine Cyclic Monophosphate Molecular Similarity 
Cyclic Nucleotide Structural Differentiation of Compounds Modulating Apoptosis and Drug Resistance被引量：2
《Journal of Biosciences and Medicines》2021年第8期10-28,共19页Wynford Robert Williams 
Carcinogenesis is associated with malfunction in the cGMP-mediated regulation of cytosolic Ca2+ and reactive oxygen species. Chemotherapy resistant cancer cells are re-sensitised to apoptosis by the action ...
关键词：Cancer CHEMOTHERAPY Guanosine Cyclic Monophosphate Molecular Similarity Multidrug Resistance 
Liraglutide suppresses the proliferation of endometrial cancer cells through the adenosine 5'-monophosphate(AMP)-activated protein kinase signaling pathway被引量：2
《Chinese Medical Journal》2021年第5期576-578,共3页Xin-Xin Zhu Zong-Hao Feng Lin-Zhi Liu Yan Zhang 
This work was supported by a grant from the National Natural Science Foundation of China(No.81272870).
This study investigated the effect of liraglutide(an analog of human glucagon-like peptide-1[GLP-1])on the proliferation of Ishikawa(IK)and human endometrial carcinoma(HEC)-IB endometrial cancer(EC)cell lines,identifi...
关键词：ENDOMETRIAL cancer PROGESTERONE 
The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3',5'-monophosphate(Epac)for central nervous system trauma被引量：3
《Neural Regeneration Research》2021年第3期460-469,共10页Alba Guijarro-Belmar Dominik Mateusz Domanski Xuenong Bo Derryck Shewan Wenlong Huang 
supported by Scottish Rugby Union funding to WH and DS;the NRB PhD scholarship from the International Spinal Rsesarch Trust to AGB;a Hot-Start Scholarship from the University of aberdeen to DD。
Millions of people worldwide are affected by traumatic spinal cord injury,which usually results in permanent sensorimotor disability.Damage to the spinal cord leads to a series of detrimental events including ischaemi...
关键词：ASTROCYTES axonal regeneration cAMP central nervous system regeneration Epac glial scar microglia NEUROINFLAMMATION neurons spinal cord spinal cord injury traumatic spinal cord injury 
全选清除导出
共4页<1234>
检索报告 对象比较 聚类工具 使用帮助 返回顶部