Supported by the National Natural Science Foundation of China(No.81774068);the Natural Science Foundation of Zhejiang Province(Youth Project,No.LQ19H290002)。
Graft-versus-host disease(GVHD)is the most common complication after allogeneic hematopoietic stem cell transplantation,and also an important factor affecting the survival and quality of life in patients after transpl...
the National Natural Science Foundation of China (Nos.81873445, 81470342, and 81670168);the Foundation for Innovative Research Groups of the National Natural Science Foundation of China (No.81621001);the Key Program of the National Natural Science Foundation of China (Nos.81530046 and 81230013).
Human leukocyte antigen (HLA)-matched donors for hematopoietic stem cell transplantation (HSCT) have long been scarce in China. Haploidentical (haplo) donors are available for the vast majority of patients, but toxici...
supported by grants from the National Institute of Allergy and Infectious Diseases, National Institutes of Health (R37 AI34495);National Heart, Lung, and Blood Institute, National Institutes of Health (R01 HL56067 and R01 HL11879);National Cancer Institute, National Institutes of Health (P01 CA142106 and P01 CA065493)
The most common approaches to prevent and treat graft-versus-host disease (GVHD) are intended to deplete or suppress the T cells capable of mediating or supporting alloresponses;however, this renders the recipients fu...
Mesenchymal stem cells(MSCs) have a powerful immunosuppressive capacity, and they have been used to treat numerous immune diseases, such as refractory graft-versus-host disease. Nevertheless, there are conflicting cli...
Aim Allogeneic hematopoietic stem cell transplantation (HSCT) has curable potential for hematopoietic malignancies through graft-versus-leukemia (GVL) effects but is often associated with life-threatening graft-ve...
Allogeneic bone marrow transplant is a life-saving procedure for adults and children that have high-risk or relapsed hematological malignancies. Incremental advances in the procedure, as well as expanded sources of do...
Supported by Grant from the National Center for Global Health and Medicine
Here,we report a case of fulminant gastrointestinal graft-versus-host disease(GI-GVHD) with cytomegalovirus(CMV) infection in 44-year-old woman.Despite the difficulties associated with the treatment of GIGVHD and GI-C...
AIM: To determine the factors affecting mortality in pa- tients who developed graft-versus-host disease (GvHD) after liver transplantation (LT). METHODS: We performed a review of studies of GvHD following LT pub...
Supported by the National Natural Science Foundation of China (Grant No. 30971300)
To explore the effect and pathogenssis of acute graft-versus-host disease (aGVHD) on early diffuse lung injury in allogeneic hematopoietic stem cell transplantation (allo-HSCT), we established an aGVHD model of C57BL/...
Acute graft-versus-host disease(GVHD) occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues.About 35%-50% of hematopoietic stem cell transplant(HSCT) r...