support from the NSFC(21702035);the National Key Research and Development Program of China(Grant No.2018YFA0507900);the Pearl River Talents Recruitment Program of Guangdong Province(2017GC010600);the Science and Technology Program of Guangzhou(201804010455)is greatly appreciated.
Mutually complementary regiodivergent Brønsted acid-catalyzed atom-economical[2+2]cycloadditionand ene reactions of 1,2-dihydroquinolines with 3-olefinic oxindoles are reported.In the presence of achiral phosphoramide...
Financial support from the NSFC(21925109,21772170,21801223,and 21772179);the China Postdoctoral Science Foundation(No.2020M671689);the Center of Chemistry for Frontier Technologies of Zhejiang University is gratefully acknowledged.
Transition-metal-catalyzed asymmetric C–H functionalization has gradually emerged as a powerful tool for the creation of structural and chiral complexity in an atom-and step-economical fashion.The nature of this stra...
support of the National Natural Science Foundation(21971094).
The first N-heterocyclic carbene-catalyzed enantioselective dearomatizing annulation of benzoxazoleswith α,β-unsaturated aldehydes has been achieved. The reaction was found to be compatible with a widerange of benzo...
This work has been supported by the following Brazilian research funding agencies:Coordenacao de Aperfeiçoamento de Pessoal de Nivel Superior(CAPES),Conselho Nacional de Desenvolvimento Cientifico e Tecnológico(CNPq,project PQ-2017/311070/2017-5);Fundacao de AmparoàPesquisa do Estado do Rio de Janeiro(FAPERJ,CNE-FAPERJ E-26/203.059/2016);GSC acknowledges the scholarship from CAPES(grant 88887.517631/2020-00);FCD is grateful for the scholar-ship from CNPq(grant 142066/2019-2);CN gratefully acknowledges financial support from the Spanish Ministerio de Economia y Competitividad(MINECO),Agencia Estatal de Investigacion(AEI);Fondo Europeo de Desarrollo Regional(FEDER,EU)(projects CTQ2016-76782-P,CTQ2016-81797-REDC and PID2019-107268GB-I00);the University of Alicante.
Asymmetric hydrogenation(AH)and asymmetric transfer hydrogenation(ATH)are versatile synthetic methodologies widely employed in the preparation of chiral compounds.In this review,we explore the applications of AH and A...
Financial support from the National Natural Science Foundation of China(Grant No.22171143,21472096 and J1103306)is gratefully acknowledged.
Chiral 3-hydroxyoxindoles are biologically important molecular motifs which are frequently present in natural products and artificial compounds.Herein,we report an ultraviolet light-driven asymmetric vinylogous aldol ...
support from the National Natural Science Foundation of China(21931010);the National Key R&D Program of China(grant No.2017YFA0207302).
A seven-step total synthesis of(+)-cylindricine D and epi-cylindricine D is described.The efficiency relies on the highly diastereoselective reductive bis-functionalization of N,O-protected(S)-pyroglutaminol by our re...
the National Natural Science Foundation of China(No.21871270,21790332 and 21521002);CAS(QYZDJSSWSLH023);the Youth Innovation Promotion Association,Chinese Academy of Sciences(201708)for financial support.
An efficient Ru-catalyzed enantioselective hydrogenation of quinoxalinone and quinazolinone derivatives has been successfully developed,providing a straightforward and facile access to chiral dihydroquinoxalinones and...
the National Natural Science Foundation of China(no.81872723 and 82073679).
An efficient and practical organocatalytic asymmetric[3+2]cycloaddition of difluoromethylated ketoimines and methyleneindolinones catalyzed by a quinine-derived squaramide has been disclosed.Under mild conditions,a br...
the National Natural Science Foundation of China(No.22001260);the Natural Science Foundation of Guangdong Province(No.2021A1515010016);the Outstanding Talents Research Start-up Foundation of Xuzhou Medical University(No.D2020016).
Catalytic enantioselective direct C–H bond functionalization of electron-deficient N-containing heteroarenes represents one of the most straightforward and powerful protocols to construct diverse enantioenriched high...
supported by the“Fundamental Research Funds for Central Universities”(No.1191329135);the Key Laboratory Construction Program of Xi’an Municipal Bureau of Science and Technology(No.201805056ZD7CG40);the starting fund of Xi’an Jiao Tong University(No.7121182002).
Based on palladium-catalyzed allylic amination reaction,the first general example of enantioselective formation of a tetrazole-bearing quaternary stereocenter has been developed.The protocol uses ambivalent tetrazole ...