PHLOROGLUCINOL

作品数：24被引量：39H指数：4
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相关领域：医药卫生农业科学更多>>
相关作者：王烨张力群刘九成张伟李海昌更多>>
相关机构：中国农业大学清华大学玉泉医院更多>>
相关期刊：《湖南师范大学学报（医学版）》《Science China(Life Sciences)》《Chinese Journal of Natural Medicines》《Open Journal of Optimization》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划天津市自然科学基金中国博士后科学基金更多>>
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Discovery of unusual phloroglucinol-triterpenoid adducts from Leptospermum scoparium and Xanthostemon chrysanthus by building blocks-based molecular networking被引量：1
《Chinese Chemical Letters》2024年第6期353-357,共5页Jinyan Zhang Fen Liu Qian Jin Xueyi Li Qiong Zhan Mu Chen Sisi Wang Zhenlong Wu Wencai Ye Lei Wang 
supported by the Guangdong Basic and Applied Basic Research Foundation(Nos.2020B1515120066 and 2022A1515010010);the National Natural Science Foundation of China[Nos.82293681(82293680)and 82273822];the Science and Technology Key Project of Guangdong Province(No.2020B1111110004);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(No.2017BT01Y036);the Fundamental Research Funds for the Central Universities;the support of K.C.Wong Education Foundation。
The first phloroglucinol-triterpenoid hybrids,myrtphlotritins A-E(1-5),were rapidly recognized and isolated from two species of Myrtaceae by employing the building blocks-based molecular network(BBMN)strategy.Compound...
关键词：Phloroglucinol-triterpenoid adduct MYRTACEAE Building blocks-based molecular network Biomimetic synthesis Antiviral activity Anti-inflammatory activity 
Optimization of a Method for the Simultaneous Determination of Phloroglucinol and Trimethylphloroglucinol by High Performance Liquid Chromatography in Routine Use in a Pharmaceutical Industry in Abidjan
《Open Journal of Optimization》2023年第2期11-24,共14页Jean-Kisito Kouamé Mariette Désirée Yéhé Claude Bérenger Ngalemo Ngantchouko Amani Germain Brou Carine Nina Ablé Aya Mélissa Diane Kouadio Bi Gogoua Désiré Vagny Vincent De Paul Ovi Christophe N’cho Amin Gildas Komenan Gbassi 
In order to provide the population with safe, effective and good quality medicines, the pharmaceutical industries, before releasing batches of their products into the pharmaceutical circuit, put in place internal dosa...
关键词：PHG TPHG Pharmaceutical Industry Chromatographic Profile Chromatographic Peak 
Carbon nanodots:A metal-free,easy-to-synthesize,and benign emitter for light-emitting electrochemical cells被引量：1
《Nano Research》2022年第6期5610-5618,共9页Yongfeng Liu Shi Tang Xiuyu Wu Nicolas Boulanger Eduardo Gracia-Espino Thomas Wågberg Ludvig Edman Jia Wang 
support from J.C.Kempes Minnes Stipendiefond(No.SMK-1849.1);the Swedish Energy Agency(Nos.45419-1,46523-1,and 50779-1);the Swedish Research Council(Nos.2017-04380,2017-04862,2018-03937,and 2019-02345);the Swedish Foundation for Strategic Research,Stiftelsen Olle Engkvist Byggmästare(Nos.186-0637 and 193-0578);Bertil&Britt Svenssons stiftelse för belysningsteknik,the Swedish Foundation for International Cooperation in Research and Higher Education via an Initiation Grant for Internationalization(No.2019-8553)。
Light-emitting electrochemical cells(LECs)can be fabricated with cost-efficient printing and coating methods,but a current drawback is that the LEC emitter is commonly either a rare-metal complex or an expensive-to-sy...
关键词：carbon nanodot light-emitting electrochemical cell PHLOROGLUCINOL sustainable synthesis solution-based fabrication 
Discovery of Eucalyptin C,derived from the fruits of Eucalyptus globulus Labill.,as a novel selective PI3Kγinhibitor for immunosuppressive treatment被引量：1
《Chinese Journal of Natural Medicines》2021年第11期844-855,共12页HU Xiao-Long SHEN Wei WANG Rong LONG Huan WANG Quan FENG Jia-Hao PHAM Thi-Anh XIONG Fei YE Wen-Cai WANG Hao 
This work was supported by China Postdoctoral Science Foundation(Nos.2019M662006 and 2019TQ0357);the National Natural Science Foundation of China(Nos.81973206,81803392 and 81573309);the Major National Science and Technology Projects of the Chinese Thirteen Five-Year Plan(No.2017ZX09309024);the Funding of Double First-rate Discipline Innovation Team(Nos.CPU2018PZQ17,CPU2018PZQ18,and CPU2018GF05);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(No.2017BT01Y036);the Research and Innovation Project for College Graduates of Jiangsu Province 2017(No.KYCX170694);the National College Student Innovation Project for the R&D of Novel Drugs(No.201710316100);Jiangsu Province Graduate Student Training Innovation Project(No.KYLX16_1208).
The fruits of Eucalyptus globulus Labill.are known to have a plenty of medicinal properties,such as anti-tumor,anti-inflammatory,and immunosuppressive activity.Our previous study found that the phloroglucinol-sesquite...
关键词：Phosphoinositide 3-kinase-γ(PI3Kγ) Eucalyptin C Immunosuppressive effects Activated spleen cells Phloroglucinol-sesquiterpene adducts 
Guajamers A-I, Rearranged Polycyclic Phloroglucinol Meroterpenoids from Psidium guajava Leaves and Their Antibacterial Activity被引量：4
《Chinese Journal of Chemistry》2021年第5期1129-1137,共9页Ji-Wu Huang Chuang-Jun Li Jing-Zhi Yang Chuan Li Yu Zhang Ke Liu Yue Yu Jian-Dong Jiang Dong-Ming Zhang 
the National Natural Science Foundation of China(No.21772234);the National New Drug Innovation Major Project of China(Nos.2018ZX09735006,2018ZX09711001-001,and 2018ZX09711001-002-010);the independent project of State Key Laboratory of Bioactive Substance and Function of Natural Medicines(No.GTZA201803).
Eight new polycyclic phloroglucinol meroterpenoids guajamers A-H(1-8),a methylated benzoylphloroglucinol meroterpenoid guajamer I(9)representing a new skeleton,and two known analogues(10 and 11)were isolated from the ...
关键词：Psidium guajava MEROTERPENOIDS X-ray crystal structure Structural elucidation Antibacterial activity 
Four New Phloroglucinol-Terpene Adducts from the Leaves of Myrciaria cauliflora被引量：1
《Natural Products and Bioprospecting》2021年第1期111-118,共8页Ming Chen Jia-Qing Cao Wen-Jing Wang Ni-Ping Li Yan Wu Lei Wang Wen-Cai Ye 
supported by the National Key R&D Program of China(No.2017YFC1703800);the Program for the National Natural Science Foundation of China(Nos.81822042,81630095);the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(2017BT01Y036);Key-Area Research and Development Program of Guangdong Province(2020B1111110004);the High-performance Computing Platform of Jinan University.
Myrcauones A-D(1-4),four new phloroglucinol-terpene adducts were isolated from the leaves of Myrciaria cauliflora.Their structures with absolute configurations were elucidated by combination of spectroscopic analysis,...
关键词：Myrciaria cauliflora Phloroglucinol-terpene adducts Antibacterial activity 
The antiangiogenic phloroglucinol hyperforin inhibits the secretion of proMMP-2, proMMP-9 and VEGF-A during apoptosis of primary acute myeloid leukemia cells
《Journal of Cancer Metastasis and Treatment》2021年第1期588-603,共16页Faten Merhi Ruoping Tang Ollivier Legrand Florence Nguyen-Khac Santos A.Susin Brigitte Bauvois 
supported by the French National Institute of Health and Medical Research(INSERM).This research received no external funding.
Aim:Angiogenesis is observed in acute myeloid leukemia(AML).AML cells abnormally proliferate and are resistant to death.Positive regulators of angiogenesis,VEGF-A and matrix metalloproteinases(MMPs)2 and 9 are markers...
关键词：Acute myeloid leukemia APOPTOSIS HYPERFORIN matrix metalloproteinase VEGF SECRETION 
Effects of solvents and temperature on spherulites of self-assembled phloroglucinol tristearate
《Frontiers of Chemical Science and Engineering》2020年第3期389-396,共8页Yawen Yao Sabine Rosenfeldt Kai Zhang 
Y.Y.thanks the China Scholarship Council(CSC)for financial support.K.Z.thanks Georg-August-University of Goettingen for the Anschubfinanzierung(Funding for the Promotion of Young Academics of University of Goettingen)and Fonds der Chemischen Industrie(FCI)for the financial support.The authors declare no conflicts of interest.
Herein,phloroglucinol tristearate(PhgTS)was used to study the crystallization process due to its unique symmetric structure containing a benzene ring and three aliphatic chains.Spherulites of crystallized PhgTS from f...
关键词：PHLOROGLUCINOL tristearate aprotic and protic solvent SELF-ASSEMBLY SPHERULITES 
Phloroglucinol derivative compound 21 attenuates cuprizoneinduced multiple sclerosis mice through promoting remyelination and inhibiting neuroinflammation被引量：3
《Science China(Life Sciences)》2020年第6期905-914,共10页Zhe Zhao Xiu-qi Bao Zihong Zhang Hui Liu Dan Zhang 
the National Natural Sciences Foundation of China (81630097 and 81773718);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (2016I2M-3-011);the Chinese Academy of Medical Sciences Fundamental Research Funds for the Central Universities (2018RC350002);the National Major Scientific and Technological Special Project for “Significant New Drugs Development” during the Thirteenth Five-year Plan Period (2018ZX09711001003-005, 2018ZX09711001-008-005 and 2018ZX09711001-003-020)。
Multiple sclerosis(MS) is a chronic autoimmune demyelinating disease in the central nervous system. The myelin loss is mainly caused by dysfunction of oligodendrocytes and inflammatory responses of microglia and astro...
关键词：multiple sclerosis OLIGODENDROCYTES DEMYELINATION microglia ASTROCYTES 
Euphoractone,a cytotoxic meroterpenoid with an unusual entabietane-phloroglucinol skeleton,from Euphorbia fischeriana Steud.被引量：4
《Chinese Chemical Letters》2020年第2期431-433,共3页Rihan Xie Linsheng Li Xiaona Fan Jiachen Zi 
financially supported by the National Natural Science Foundation of China(No.81673530);Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(No.2017BT01Y036)。
A novel meroterpenoid,euphoractone(1),was isolated from the extracts of the roots of Euphorbia fischeriana Steud.Its structure was determined by spectroscopic methods and X-ray crystallography.1 possesses an unusual e...
关键词：EUPHORBIA fischeriana Meroterpenoid ent-Abietane PHLOROGLUCINOL Euphoractone Cytotoxicity 
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