Supported by the National Natural Science Foundation of China(No.81974518);Natural Science Foundation of Jiangsu Province(No.19KJB360019);Innovative Training Program for College Students in Jiangsu Province(No.202010304125Y)。
Objective:To elucidate the mechanism of Lizhong Decoction(LZD)in treating dextran sodium sulfate(DSS)-induced colitis in mice based on metabonomics.Methods:Thirty-six mice were randomly divided into 6 groups,including...
BACKGROUND Gestational diabetes mellitus(GDM)is a metabolic disease with an increasing annual incidence rate.Our previous observational study found that pregnant women with GDM had mild cognitive decline.AIM To analyz...
financially supported by the National Natural Science Foundation of China (81673598, 81973483, 82003948);Natural Science Foundation of Zhejiang Province (LQ21H280002);The National Key Research and Development Program of China (2018YFC1707000);the National traditional Chinese medicine industry special project (2015468002-2);National Standardization Program for Chinese Medicine (ZYBZH-Y-SC-40);Zhejiang Chinese Medicine University School-level Scientific Research Fund for Talents (2020ZR14)。
Background: Curcuma wenyujin rhizome(CWR) is a commonly used Chinese herbal medicine for treating blood stasis in China for 1000 of years. However, the underlying mechanism of CWR remains unclear. Aims and Objectives:...
supported by the National Natural Science Foundation of China [Grant No.81273079].
Objective Di-(2-ethylhexyl) phthalate(DEHP) is a ubiquitous environmental contaminant.As an endocrine disruptor,it seriously threatens human health and ecological environmental safety.This study examines the impact of...
Hepatocellular carcinoma(HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the opti...
Objective To observe metabolomic changes in urine of chronic superficial gastritis(CSG)patients with Pi-qi deficiency syndrome(PQDS)or Pi-Wei dampness-heat syndrome(PWDHS),thereby providing scientific evidence for syn...
Project(20805045)supported by National Natural Science Foundation of China
A metabonomic approach was undertaken in order to detect urinary endogenous and exogenous metabolites and to evaluate the effects of passive exposure to cigarette sidestream smoke on rats. Urinary samples from three g...
financially supported by the Natural Science Foundation of China(No.31272600)
This study aimed at determining the effects of Angelica sinensis(AS) on urinary metabolites in blood deficiency mice and exploring its replenishing blood mechanism. Gas chromatography–mass spectrometry(GC-MS) was app...
Supported by the Chinese Academy of Sciences (Grant No: KZCX2-YW-420-21);the National High Technology Research and Development Program of China (Grant No: 2006AA06Z424);the National Natural Science Foundation of China (Grant Nos: 40590392 and 20575074)
Nuclear magnetic resonance (NMR) spectroscopic analysis of metabonome/metabolome has widespread applications in biomedical science researches. However, most of NMR resonances for urinary metabolites remain to be fully...
Metabonomics analysis of the urine of rats with Qi deficiency and blood stasis syndrome has been performed by comparison with those of normal rats based on NMR techniques. The relative contents of formate,creatinine,2...