financially supported by grants from the Macao Science and Technology Development Fund(0032/2018/AFJ,0003/2019/AKP,and 0010/2020/A1);the Key Program in Emerging Industry of the Hunan Department of Science&Technology(2014GK1058);funded by Dr.Neher’s Biophysics Laboratory for Innovative Drug Discovery(001/2020/ALC)supported by the Macao Science and Technology Development Fund。
Sinomenine(SIN)is commonly used as part of rheumatoid arthritis(RA)therapy in China,but there is still no published evidence of the efficacy of SIN monotherapy.This work investigates the efficacy and safety of SIN in ...
supported by National Key R&D Program(2017YFD0500503);Postdoctoral Science Foundation(BX20180096);Hunan Province Science and Technology Projects(2017RS3059);Innovation Province Project(2019RS3021)in China;Texas A&M AgriLife Research(H-8200)in USA
L-proline(Pro)is a precursor of ornithine,which is converted into polyamines via ornithine decarboxylase(ODC).Polyamines plays a key role in the proliferation of intestinal epithelial cells.The study investigated the ...
Curcumin the active component of turmeric is widely used as an anticancer agent for treating many human cancers. This study aimed at the extraction of curcumin from Curcuma Longa and investigates its therapeutic effec...
Supported by Universidad Nacional de Rosario(UNR),BIO 272,Resol.C.S.,No.677/2013;Agencia Nacional de Promoción Científica y Tecnológica(ANPCyT),PICT-03-14492,BID 1728 OC/AR(Argentina);a grant from Regione Autonoma FriuliVenezia Giulia,Italy
AIM To determine the influence of the construction design over the biological component's performance in an experimental bio-artificial liver(BAL) device.METHODS Two BAL models for liver microorgans(LMOs) were constru...
supported by grants from Universidad Nacional del Litoral(U.N.L)(CAI+D,2011),República Argentina.
Nucleic acids-based therapies have recently developed as next-generation agents for treating and preventing viral infection, cancer, and genetic disorders, but their use is still limited due to its relatively poor del...
Hepatic insufficiency is a fatal liver disease with a significant decrease in functioning hepatocytes. If hepatocytes could be generated from human induced pluripotent stem(hi PS) cells and transplanted into patients ...
DL-ornithine hydrochloride rods (3 ×10 mm) were studied to be a radiation sensitive material for EPR dosimetry. The rods have specified EPR signal developed under irradiation and its intensity increases with the incr...
The effect of oral L-ornithine hydrochloride (0.1 g/kg BW) on energy expenditure during a rest period from 120 to 180 min after resistance exercise was evaluated by indirect calorimetry. Healthy male subjects who have...
Objective: Corynebacterium crenatum AS1.542, a Gram-positive bacterium and indigenous nonpatho-genic corynebacteria, is widely exploited for the in-dustrial production of amino acids. The objective of this paper is to...